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2023 (engelsk)Inngår i: BMC Pregnancy and Childbirth, ISSN 1471-2393, E-ISSN 1471-2393, Vol. 23, nr 1, artikkel-id 237Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]
Background Pregnancy and childbirth are significant events in many women's lives, and the prevalence of depressive symptoms increases during this vulnerable period. Apart from well documented cognitive, affective, and somatic symptoms, stress and depression are associated with physiological changes, such as reduced heart-rate variability (HRV) and activation of the inflammatory response system. Mindfulness Based Interventions may potentially have an effect on both HRV, inflammatory biomarkers, and self-assessed mental health. Therefore, the aim of this study was to assess the effects of a Mindfulness Childbirth and Parenting (MBCP) intervention on HRV, serum inflammatory marker levels, through an RCT study design with an active control group. Methods This study is a sub-study of a larger RCT, where significant intervention effects were found on perinatal depression (PND) and perceived stress. Participants were recruited through eight maternity health clinics in Stockholm, Sweden. In this sub-study, we included altogether 80 women with increased risk for PND, and blood samples and HRV measures were available from 60 of the participants (26 in the intervention and 34 in the control group). Results Participants who received MBCP reported a significantly larger reduction in perceived stress and a significantly larger increase in mindfulness, compared to participants who received the active control treatment. However, in this sub-study, the intervention had no significant effect on PND, inflammatory serum markers or measures of HRV. Conclusions No significant differences were found regarding changes in HRV measures and biomarkers of inflammation, larger studies may be needed in the future.
sted, utgiver, år, opplag, sider
BioMed Central (BMC), 2023
Emneord
Mindfulness, Pregnancy, Depression, Inflammation, Heart rate variability
HSV kategori
Identifikatorer
urn:nbn:se:uu:diva-503247 (URN)10.1186/s12884-023-05528-2 (DOI)000968955100002 ()37038176 (PubMedID)
Forskningsfinansiär
Swedish Research Council, 2014-10167
2023-06-142023-06-142023-06-14bibliografisk kontrollert