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Publications (10 of 83) Show all publications
Weiss, M. G., Nielsen, P. H., James, S., Thelin, S. & Modrau, I. S. (2021). Clinical Outcomes After Surgical Revascularization Using No-Touch Versus Conventional Saphenous Vein Grafts: Mid-Term Follow-Up of Propensity Score Matched Cohorts. Seminars in Thoracic and Cardiovascular Surgery, 35(2), 228-236
Open this publication in new window or tab >>Clinical Outcomes After Surgical Revascularization Using No-Touch Versus Conventional Saphenous Vein Grafts: Mid-Term Follow-Up of Propensity Score Matched Cohorts
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2021 (English)In: Seminars in Thoracic and Cardiovascular Surgery, ISSN 1043-0679, E-ISSN 1532-9488, Vol. 35, no 2, p. 228-236Article in journal (Refereed) Published
Abstract [en]

Previous studies have demonstrated superior patency of no-touch as compared to conventional saphenous vein grafts in coronary artery bypass grafting. We aimed to compare mid-term clinical outcomes of both techniques in a large cohort of routine patients. We identified all patients undergoing nonemergent primary coronary artery bypass grafting with either no-touch or conventional saphenous vein grafts at our institution between 2000 and 2020. Propensity score matching was used to create adjusted cohorts based on 5288 eligible patients. The primary outcome was the combined endpoint of all-cause mortality and repeat revascularization. Secondary outcomes were individual rates of all-cause mortality and repeat revascularization, surgical complications, and short-term mortality. Propensity score matching resulted in cohorts of no-touch (n = 923) and conventional (n = 923) saphenous vein grafted patients with comparable baseline characteristics. Mean follow-up time was significantly shorter for the no-touch compared to the conventional cohort (4.9 ± 2.3 vs 8.3 ± 2.6 years, P < 0.001). Up to 7-year follow-up, neither the rate of the primary composite endpoint nor death differed significantly between the cohorts. The rate of repeat revascularization was significantly higher in patients in the no-touch cohort (12.9% vs 9.3% at 7-year follow-up, P = 0.022. Post-hoc analysis of percutaneous coronary intervention during follow-up revealed comparable rates of saphenous vein graft failure (no-touch 42/923 (4.6%) vs conventional 32/923 (3.5%), P = 0.286). In this large propensity score matched registry study, coronary artery bypass with no-touch compared to conventional saphenous vein grafting did neither enhance mid-term survival nor reduce the rate of repeat revascularization.

Place, publisher, year, edition, pages
Elsevier, 2021
Keywords
No-touch saphenous vein grafts, Coronary artery bypass graft surgery, Propensity score matching, Clinical outcomes, Mid-term follow-up
National Category
Cardiac and Cardiovascular Systems Surgery
Identifiers
urn:nbn:se:uu:diva-464507 (URN)10.1053/j.semtcvs.2021.12.002 (DOI)001012878600001 ()34879223 (PubMedID)
Available from: 2022-01-14 Created: 2022-01-14 Last updated: 2023-07-17Bibliographically approved
Lindblom, R., Tovedal, T., Norlin, B., Hillered, L., Englund, E. & Thelin, S. (2021). Mechanical Reperfusion Following Prolonged Global Cerebral Ischemia Attenuates Brain Injury. Journal of Cardiovascular Translational Research, 14, 338-347
Open this publication in new window or tab >>Mechanical Reperfusion Following Prolonged Global Cerebral Ischemia Attenuates Brain Injury
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2021 (English)In: Journal of Cardiovascular Translational Research, ISSN 1937-5387, E-ISSN 1937-5395, Vol. 14, p. 338-347Article in journal (Refereed) Published
Abstract [en]

Previous experiments demonstrated improved outcome following prolonged cerebral ischemia given controlled brain reperfusion using extracorporeal circulation. The current study further investigates this. Young adult pigs were exposed to 30 min of global normothermic cerebral ischemia, achieved through intrathoracic clamping of cerebral arteries, followed by 20 min of isolated mechanical brain reperfusion. Leukocyte-filtered blood was delivered by a roller-pump at fixed pressure and flow. One experimental group additionally had a custom-made buffer solution delivered at 1:8 ratio with the blood. Hemodynamics including intracranial pressure were monitored. Blood gases were from peripheral arteries and the sagittal sinus, and intraparenchymal brain microdialysis was performed. The brains were examined by a neuropathologist. The group with the added buffer showed lower intracranial pressure as well as decreased intraparenchymal glycerol and less signs of excitotoxicity and ischemia, although histology revealed similar degrees of injury. A customized mechanical reperfusion improves multiple parameters after prolonged normothermic global cerebral ischemia.

Place, publisher, year, edition, pages
SpringerSPRINGER, 2021
Keywords
Global cerebral ischemia, Reperfusion, Mechanical circulation
National Category
Anesthesiology and Intensive Care Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-450612 (URN)10.1007/s12265-020-10058-9 (DOI)000549659000001 ()32681452 (PubMedID)
Available from: 2021-08-17 Created: 2021-08-17 Last updated: 2024-01-15Bibliographically approved
Budtz-Lilly, J., Vikholm, P., Wanhainen, A., Astudillo, R., Thelin, S. & Mani, K. (2021). Technical eligibility for endovascular treatment of the aortic arch after open type A aortic dissection repair. Journal of Thoracic and Cardiovascular Surgery, 162(3), 770-777
Open this publication in new window or tab >>Technical eligibility for endovascular treatment of the aortic arch after open type A aortic dissection repair
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2021 (English)In: Journal of Thoracic and Cardiovascular Surgery, ISSN 0022-5223, E-ISSN 1097-685X, Vol. 162, no 3, p. 770-777Article in journal (Refereed) Published
Abstract [en]

Objective

The objective was to report on the technical eligibility of patients previously treated for Stanford type A aorta dissection for endovascular aortic arch repair based on contemporary anatomic criteria for an arch inner-branched stent graft.

Methods

All patients treated for type A aorta dissection from 2004 to 2015 at a single aortic center were identified. Extent of repair and use of circulatory arrest were reported. Survival and reoperation were assessed using Kaplan–Meier and competing risk models. Anatomic assessment was performed using 3-dimensional computed tomography imaging software. Primary outcome was survival of 1 year or more and fulfillment of the arch inner-branched stent graft anatomic criteria.

Results

A total of 198 patients were included (158 DeBakey I, 32 DeBakey II, and 8 intramural hematoma). Mortality was 30 days (16.2%), 1 year (16.3%), and 10 years (45.0%). A total of 129 patients had imaging beyond 1 year (mean, 47.8 months), and 89 patients (69.0%) were eligible for arch inner-branched stent grafting. During follow-up, 19 patients (14.7%) met the threshold criteria for aortic arch treatment, of whom 14 (73.7%) would be considered eligible for arch inner-branched stent graft. Patients who underwent type A aorta dissection repair with circulatory arrest and no distal clamp were more often eligible for endovascular repair (88.8%) than those operated with a distal clamp (72.5%; P = .021). Among patients who did not meet the arch inner-branched stent graft anatomic criteria, the primary reasons were mechanical valve (40%) and insufficient proximal seal (30%).

Conclusions

More than two-thirds of patients post–type A aorta dissection repair are technically eligible for endovascular arch inner-branched stent graft repair. The development of devices that can accommodate a mechanical aortic valve and a greater awareness of sufficient graft length would significantly increase availability.

Keywords
endovascular aortic arch, post-type A aortic dissection, inner branched
National Category
Surgery Cardiac and Cardiovascular Systems
Research subject
Surgery
Identifiers
urn:nbn:se:uu:diva-393182 (URN)10.1016/j.jtcvs.2019.12.113 (DOI)000692831000027 ()
Available from: 2019-09-17 Created: 2019-09-17 Last updated: 2021-11-01Bibliographically approved
Ragnarsson, S., Janiec, M., Modrau, I. S., Dreifaldt, M., Ericsson, A., Holmgren, A., . . . Thelin, S. (2020). No-touch saphenous vein grafts in coronary artery surgery (SWEDEGRAFT): Rationale and design of a multicenter, prospective, registry-based randomized clinical trial. American Heart Journal, 224, 17-24
Open this publication in new window or tab >>No-touch saphenous vein grafts in coronary artery surgery (SWEDEGRAFT): Rationale and design of a multicenter, prospective, registry-based randomized clinical trial
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2020 (English)In: American Heart Journal, ISSN 0002-8703, E-ISSN 1097-6744, Vol. 224, p. 17-24Article in journal (Refereed) Published
Abstract [en]

The SWEDEGRAFT study (ClinicalTrials.gov Identifier: NCT03501303) tests the hypothesis that saphenous vein grafts (SVGs) harvested with the "no-touch" technique improves patency of coronary artery bypass grafts compared with the conventional open skeletonized technique. This article describes the rationale and design of the randomized trial and baseline characteristics of the population enrolled during the first 9 months of enrollment. The SWEDEGRAFT study is a prospective, binational multicenter, open-label, registry-based trial in patients undergoing first isolated nonemergent coronary artery bypass grafting (CABG), randomized 1:1 to no-touch or conventional open skeletonized vein harvesting technique, with a planned enrollment of 900 patients. The primary end point is the proportion of patients with graft failure defined as SVGs occluded or stenosed >50% on coronary computed tomography angiography at 2 years after CABG, earlier clinically driven coronary angiography demonstrating an occluded or stenosed >50% vein graft, or death within 2 years. High-quality health registries and coronary computed tomography angiography are used to assess the primary end point. The secondary end points include wound healing in the vein graft sites and the composite outcome of major adverse cardiac events during the first 2 years based on registry data. Demographics of the first 200 patients enrolled in the trial and other CABG patients operated in Sweden during the same time period are comparable when the exclusion criteria are taken into consideration.

Place, publisher, year, edition, pages
MOSBY-ELSEVIER, 2020
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-418706 (URN)10.1016/j.ahj.2020.03.009 (DOI)000540371700003 ()32272256 (PubMedID)
Funder
Swedish Research CouncilSwedish Heart Lung Foundation
Available from: 2020-09-08 Created: 2020-09-08 Last updated: 2021-01-12Bibliographically approved
Vikholm, P., Astudillo, R. & Thelin, S. (2019). Long-term survival and frequency of reinterventions after proximal aortic surgery: a retrospective study. Paper presented at 32nd Annual Meeting of the European-Association-for-Cardio-Thoracic-Surgery, OCT 18-20, 2018, Milan, ITALY. European Journal of Cardio-Thoracic Surgery, 56(4), 722-730
Open this publication in new window or tab >>Long-term survival and frequency of reinterventions after proximal aortic surgery: a retrospective study
2019 (English)In: European Journal of Cardio-Thoracic Surgery, ISSN 1010-7940, E-ISSN 1873-734X, Vol. 56, no 4, p. 722-730Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: We sought to analyse perioperative outcome, long-term mortality, frequency and causes of reintervention, and survival benefit in a contemporary cohort of patients undergoing proximal thoracic aortic surgery.

METHODS: Participants comprised all patients undergoing open surgery for proximal thoracic aortic aneurysm (TAA) (n=319) and thoracic aortic dissection type A (TAD) (n=229) during 2005-2014 at the Department of Thoracic Surgery, Uppsala University Hospital. Long-term survival was compared to age- and sex-matched controls. Perioperative mortality and morbidity, event-free survival and causes of reoperation were also analysed.

RESULTS: Long-term mortality was normalized in patients with TAA, and a survival benefit was seen as early as 20 months when corrected for time lost due to perioperative mortality. Long-term survivors undergoing surgery for TAD, on the other hand, had a 10-year mortality of 130% [95% confidence interval (95% CI) 120-140%] compared to age- and sex-matched controls. Moreover, their event-free survival was half that of patients with TAA (hazard ratio 2.3; 95% CI 1.7-3.2). Reintervention (i.e. reoperation or thoracic endovascular aortic repair) was also twice as common in the TAD patients (odds ratio 2.0; 95% CI 1.1-3.5). The dominant causes for reoperation among TAD patients were aortic insufficiency, aortic arch aneurysm and infection.

CONCLUSIONS: Surgery for TAA is relatively safe, normalizes long-term mortality and confers an early survival benefit. However, TAD surgery carries a high risk of perioperative mortality and morbidity, as well as increased long-term mortality and risk of reintervention.

Keywords
Aortic dissection, Aortic aneurysm, Surgery, Survival, Reintervention
National Category
Surgery
Identifiers
urn:nbn:se:uu:diva-396734 (URN)10.1093/ejcts/ezz073 (DOI)000491248300012 ()30879026 (PubMedID)
Conference
32nd Annual Meeting of the European-Association-for-Cardio-Thoracic-Surgery, OCT 18-20, 2018, Milan, ITALY
Available from: 2019-11-26 Created: 2019-11-26 Last updated: 2019-11-26Bibliographically approved
Pozzoli, A., Vicentini, L., Thelin, S., Lapenna, E., Nilsson, L. & Alfieri, O. (2018). Application of cryoenergy to improve septal exposure during transaortic septal myectomy in hypertrophic obstructive cardiomyopathy. General Thoracic and Cardiovascular Surgery, 66(4), 243-245
Open this publication in new window or tab >>Application of cryoenergy to improve septal exposure during transaortic septal myectomy in hypertrophic obstructive cardiomyopathy
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2018 (English)In: General Thoracic and Cardiovascular Surgery, ISSN 1863-6705 , E-ISSN 1863-6713, Vol. 66, no 4, p. 243-245Article in journal (Refereed) Published
Abstract [en]

For the past few decades, the transaortic septal myectomy (Morrow's procedure) has been the gold standard for treating severe left ventricular outflow tract obstruction in hypertrophic obstructive cardiomyopathy (HOCM) patients. 30-day mortality has been reported at less than 1% in dedicated centers. However, in a subgroup of patients, the interventricular septal obstruction is localized very distally, below the aortic valve plane, and the transaortic approach can be very challenging. A subset of these patients can present with residual obstruction after surgery, due to inadequate length of septal excision, leading to reoperation. The aim of this work is to illustrate an original application of cryoenergy to improve the transaortic exposure of the interventricular septum and thus enable surgeons to perform very distal myectomies in HOCM patients.

Place, publisher, year, edition, pages
SPRINGER JAPAN KK, 2018
Keywords
Hypertrophic cardiomyopathy, Cryoenergy, Transaortic myectomy, Residual left ventricular outflow tract obstruction
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-351698 (URN)10.1007/s11748-017-0815-8 (DOI)000428564100010 ()28825167 (PubMedID)
Available from: 2018-06-04 Created: 2018-06-04 Last updated: 2020-11-18Bibliographically approved
Janiec, M., Friberg, Ö. & Thelin, S. (2018). Long-term clinical outcomes after coronary artery bypass grafting with pedicled saphenous vein grafts. Journal of Cardiothoracic Surgery, 13(1), Article ID 122.
Open this publication in new window or tab >>Long-term clinical outcomes after coronary artery bypass grafting with pedicled saphenous vein grafts
2018 (English)In: Journal of Cardiothoracic Surgery, E-ISSN 1749-8090, Vol. 13, no 1, article id 122Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Coronary artery bypass grafting (CABG) using saphenous vein grafts (SVG) is vitiated by poor long-term patency of the vein grafts. Pedicled SVG harvested with the "no-touch" (NT) technique have demonstrated improved patency and could confer better outcomes. We aim to compare long-term results after CABG where NT or conventional technique was used for vein graft harvesting in a hypothesis-generating registry-based study.

METHODS: Two propensity score matched cohorts (1349 patients) undergoing CABG with veins harvested with NT (NTT) or conventional (CT) technique in Sweden over the period 2005-2015 were used to compare long-term outcomes. Mortality, postoperative incidence of coronary angiography and need for reintervention was recorded and multivariable hazard ratios adjusted for risk factors were calculated.

RESULTS: The mean follow-up time (SD) was 6.8 (3.3) years for NTT and 6.6 (3.2) years for CT. The adjusted hazard ratios for death, first angiography and need for reintervention for NTT patients were (95% CI) 0.97 (0.80-1.19), 0.76 (0.63-0.93), 0.91 (0.78-1.05), and 0.91 (0.71-1.17), respectively. Failed grafts were found in 43.2% of NTT patients and 53.6% of CT patients at angiography.

CONCLUSIONS: In this study NT grafting was associated with a lower risk for repeat angiography, however no difference could be observed for mortality and need for reintervention. The earlier reported improvements in patency of NT veins could possibly be reflected in an improved clinical outcome during the first 10 years after surgery.

Keywords
CABG, Coronary artery bypass grafting, No-touch, Pedicled vein grafts
National Category
Surgery
Identifiers
urn:nbn:se:uu:diva-369713 (URN)10.1186/s13019-018-0800-z (DOI)000451321400001 ()30477543 (PubMedID)
Available from: 2018-12-17 Created: 2018-12-17 Last updated: 2023-10-04Bibliographically approved
Lindblom, R. P., Shen, Q., Axén, S., Landegren, U., Kamali-Moghaddam, M. & Thelin, S. (2018). Protein Profiling in Serum and Cerebrospinal Fluid Following Complex Surgery on the Thoracic Aorta Identifies Biological Markers of Neurologic Injury.. Journal of Cardiovascular Translational Research, 11(6), 503-516
Open this publication in new window or tab >>Protein Profiling in Serum and Cerebrospinal Fluid Following Complex Surgery on the Thoracic Aorta Identifies Biological Markers of Neurologic Injury.
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2018 (English)In: Journal of Cardiovascular Translational Research, ISSN 1937-5387, E-ISSN 1937-5395, Vol. 11, no 6, p. 503-516Article in journal (Refereed) Published
Abstract [en]

Surgery on the arch or descending aorta is associated with significant risk of neurological complications. As a consequence of intubation and sedation, early neurologic injury may remain unnoticed. Biomarkers to aid in the initial diagnostics could prove of great value as immediate intervention is critical. Twenty-three patients operated in the thoracic aorta with significant risk of perioperative neurological injury were included. Cerebrospinal fluid (CSF) and serum were obtained preoperatively and in the first and second postoperative days and assessed with a panel of 92 neurological-related proteins. Three patients suffered spinal cord injury (SCI), eight delirium, and nine hallucinations. There were markers in both serum and CSF that differed between the affected and non-affected patients (SCI; IL6, GFAP, CSPG4, delirium; TR4, EZH2, hallucinations; NF1). The study identifies markers in serum and CSF that reflect the occurrence of neurologic insults following aortic surgery, which may aid in the care of these patients.

Keywords
Biomarkers, Cardiovascular surgery, Neurologic injury, Thoracic aortic disease
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-369702 (URN)10.1007/s12265-018-9835-8 (DOI)000453355000007 ()30367354 (PubMedID)
Available from: 2018-12-16 Created: 2018-12-16 Last updated: 2019-01-15Bibliographically approved
Bagge, L., Probst, J., Jensen, S. M., Blomström, P., Thelin, S., Holmgren, A. & Blomström-Lundqvist, C. (2018). Quality of life is not improved after mitral valve surgery combined with epicardial left atrial cryoablation as compared with mitral valve surgery alone: a substudy of the double blind randomized SWEDish Multicentre Atrial Fibrillation study (SWEDMAF). Europace, 20(FI_3), f343-f350
Open this publication in new window or tab >>Quality of life is not improved after mitral valve surgery combined with epicardial left atrial cryoablation as compared with mitral valve surgery alone: a substudy of the double blind randomized SWEDish Multicentre Atrial Fibrillation study (SWEDMAF)
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2018 (English)In: Europace, ISSN 1099-5129, E-ISSN 1532-2092, Vol. 20, no FI_3, p. f343-f350Article in journal (Refereed) Published
Abstract [en]

Aims

Concomitant surgical ablation of atrial fibrillation (AF) in patients undergoing mitral valve surgery (MVS) has almost become routine despite lack of convincing information about improved quality-of-life (QOL) and clinical benefit. Quality-of-life was therefore assessed after MVS with or without epicardial left atrial cryoablation.

Methods and results

Sixty-five patients with permanent AF randomized to MVS with or without left atrial cryoablation, in the double-blinded multicentre SWEDMAF trial, replied to the Short Form 36 QOL survey at 6 and 12 months follow-up. The QOL scores at 12 month follow-up did not differ significantly between patients undergoing MVS combined with cryoablation vs. those undergoing MVS alone regarding Physical Component Summary mean 42.8 (95% confidence interval 38.3–47.3) vs. mean 44.0 (40.1–47.7), P = 0.700 or Mental Component Summary mean 53.1 (49.7–56.4) vs. mean 48.4 (44.6–52.2), P = 0.075. All patients, irrespective of allocated procedure, reached the same QOL after surgery as an age-matched Swedish general population. The Physical Component Summary in patients with sinus rhythm did also not differ from those in AF at 12 months; mean 45.4 (42.0–48.7) vs. mean 40.5 (35.5–45.6), P = 0.096) nor was there a difference in Mental Component Summary; mean 51.0 (48.0–54.1) vs. mean 49.6 (44.6–54.5), P = 0.581).

Conclusion

Left atrial cryoablation added to MVS does not improve health-related QOL in patients with permanent AF, a finding that raises concerns regarding recommendations made for this combined procedure.

Keywords
concomitant surgical ablation; mitral valve surgery; atrial fibrillation; quality of life; ablation;
National Category
Cardiac and Cardiovascular Systems
Research subject
Cardiology
Identifiers
urn:nbn:se:uu:diva-338091 (URN)10.1093/europace/eux253 (DOI)000454047100014 ()29016835 (PubMedID)
Funder
Swedish Heart Lung Foundation, 20150751Swedish Research Council, 2014-36708-117759-70
Available from: 2018-01-07 Created: 2018-01-07 Last updated: 2020-08-11Bibliographically approved
Tovedal, T., Lubberink, M., Morell, A., Estrada, S., Golla, S. S., Myrdal, G., . . . Lennmyr, F. (2017). Blood Flow Quantitation by Positron Emission Tomography During Selective Antegrade Cerebral Perfusion. Annals of Thoracic Surgery, 103(2), 610-616
Open this publication in new window or tab >>Blood Flow Quantitation by Positron Emission Tomography During Selective Antegrade Cerebral Perfusion
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2017 (English)In: Annals of Thoracic Surgery, ISSN 0003-4975, E-ISSN 1552-6259, Vol. 103, no 2, p. 610-616Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Perfusion strategies during aortic surgery usually comprise hypothermic circulatory arrest (HCA), often combined with selective antegrade cerebral perfusion (SACP) or retrograde cerebral perfusion. Cerebral blood flow (CBF) is a fundamental parameter for which the optimal level has not been clearly defined. We sought to determine the CBF at a pump flow level of 6 mL/kg/min, previously shown likely to provide adequate SACP at 20°C in pigs.

METHODS: Repeated positron emission tomography (PET) scans were used to quantify the CBF and glucose metabolism throughout HCA and SACP including cooling and rewarming. Eight pigs on cardiopulmonary bypass were assigned to either HCA alone (n = 4) or HCA+SACP (n = 4). The CBF was measured by repeated [(15)O]water PET scans from baseline to rewarming. The cerebral glucose metabolism was examined by [(18)F]fluorodeoxyglucose PET scans after rewarming to 37°C.

RESULTS: Cooling to 20°C decreased the cortical CBF from 0.31 ± 0.06 at baseline to 0.10 ± 0.02 mL/cm(3)/min (p = 0.008). The CBF was maintained stable by SACP of 6 mL/kg/min during 45 minutes. After rewarming to 37°C, the mean CBF increased to 0.24 ± 0.07 mL/cm(3)/min, without significant differences between the groups at any time-point exclusive of the HCA period. The net cortical uptake (Ki) of [(18)F]fluorodeoxyglucose after rewarming showed no significant difference between the groups.

CONCLUSIONS: Cooling autoregulated the CBF to 0.10 mL/cm(3)/min, and 45 minutes of SACP at 6 mL/kg/min maintained the CBF in the present model. Cerebral glucose metabolism after rewarming was similar in the study groups.

National Category
Surgery
Identifiers
urn:nbn:se:uu:diva-302609 (URN)10.1016/j.athoracsur.2016.06.029 (DOI)000397165400067 ()27592601 (PubMedID)
Available from: 2016-09-07 Created: 2016-09-07 Last updated: 2018-09-03Bibliographically approved
Projects
SWEDEGRAFT- a national, multicenter, prospective, randomized, registerbased, clinical trial on to-touch vein graft (NT-graft) in coronary artery surgery [2017-00214_VR]; Uppsala University
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0001-9111-115x

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