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Rastad, J
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Publications (10 of 21) Show all publications
Siilin, H., Rastad, J., Ljunggren, O. & Lundgren, E. (2008). Disturbances of calcium homeostasis consistent with mild primary hyperparathyroidism in premenopausal women and associated morbidity. Journal of Clinical Endocrinology and Metabolism, 93(1), 47-53
Open this publication in new window or tab >>Disturbances of calcium homeostasis consistent with mild primary hyperparathyroidism in premenopausal women and associated morbidity
2008 (English)In: Journal of Clinical Endocrinology and Metabolism, ISSN 0021-972X, E-ISSN 1945-7197, Vol. 93, no 1, p. 47-53Article in journal (Refereed) Published
Abstract [en]

CONTEXT: Primary hyperparathyroidism (PHPT) and associated morbidity are comprehensively assessed in elderly females; however, less is known of the disease in younger women. OBJECTIVES: Our objectives were to estimate the prevalence of mild disturbances in calcium homeostasis, which could be analogous with early PHPT, in a premenopausal population, and determine the potential presence of associated morbidity. DESIGN: Initial results from this longitudinal study are from 2002-2004. SETTING: We conducted a population-based screening of serum (s)-calcium in conjunction with routine mammography. PARTICIPANTS: Participants included premenopausal women, 40-50 yr of age (n = 1900). Cases fulfilling previously evaluated biochemical criteria for PHPT (n=214) were matched to controls (n = 214). MAIN OUTCOME MEASUREMENTS: All participants underwent investigation, including screening of parameters of calcium homeostasis, dual x-ray absorptiometry, and body mass index assessment, and filled out extensive health and quality of life (SF-36) questionnaires. Participants were divided into four groups depending on the relation between s-calcium/intact PTH. Statistical comparisons between cases and controls as well as among the four groups were performed to evaluate morbidity. RESULTS: The prevalence of assumed mild PHPT, i.e. inappropriate intact PTH value in relation to total s-calcium, was estimated to be 5.1% (n = 96). Women with mild disturbances in calcium homeostasis had statistically significant lower bone mineral density in the proximal femur and femoral neck, higher body mass index, and lower scores for vitality and general health in the analysis of SF-36. CONCLUSIONS: Mild disturbances in calcium homeostasis in premenopausal women were more prevalent than previously thought and were associated with obesity, lower bone mineral density, and decreased quality of life.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-14752 (URN)10.1210/jc.2007-0600 (DOI)000252359400011 ()18042652 (PubMedID)
Available from: 2008-01-31 Created: 2008-01-31 Last updated: 2017-12-11Bibliographically approved
Järhult, J., Rudberg, C., Larsson, E., Selvander, H., Sjövall, K., Winsa, B., . . . the TEO Study Group, . (2005). Graves´ Disease with Moderate-Severe Endocrine Ophthalmolopathy-Long Term Results of a Prospective, Randomized Study of Total or Subtotal Thyroid Resection. Thyroid, 15(10), 1157-1164
Open this publication in new window or tab >>Graves´ Disease with Moderate-Severe Endocrine Ophthalmolopathy-Long Term Results of a Prospective, Randomized Study of Total or Subtotal Thyroid Resection
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2005 (English)In: Thyroid, Vol. 15, no 10, p. 1157-1164Article in journal (Refereed) Published
Identifiers
urn:nbn:se:uu:diva-78713 (URN)
Available from: 2006-03-29 Created: 2006-03-29 Last updated: 2011-01-11
Järhult, J., Rudberg, C., Larsson, E., Selvander, H., Sjövall, K., Winsa, B., . . . Karlsson, A. (2005). Graves' disease with moderate-severe endocrine ophthalmopathy - long term results of a prospective, randomized study of total or subtotal thyroid resection.. Thyroid, 15(10), 1157-1164
Open this publication in new window or tab >>Graves' disease with moderate-severe endocrine ophthalmopathy - long term results of a prospective, randomized study of total or subtotal thyroid resection.
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2005 (English)In: Thyroid, ISSN 1050-7256, Vol. 15, no 10, p. 1157-1164Article in journal (Refereed) Published
Keywords
Adult, Aged, Female, Follow-Up Studies, Graves Ophthalmopathy/*surgery, Humans, Male, Middle Aged, Ocular Motility Disorders/etiology, Receptors; Thyrotropin/immunology, Research Support; Non-U.S. Gov't, Thyroidectomy/adverse effects/methods
Identifiers
urn:nbn:se:uu:diva-79966 (URN)16279849 (PubMedID)
Available from: 2006-04-19 Created: 2006-04-19 Last updated: 2011-01-11
Nilsson, I.-L., Aberg, J., Rastad, J. & Lind, L. (2005). Maintained normalization of cardiovascular dysfunction 5 years after parathyroidectomy in primary hyperparathyroidism.. Surgery, 137(6), 632-8
Open this publication in new window or tab >>Maintained normalization of cardiovascular dysfunction 5 years after parathyroidectomy in primary hyperparathyroidism.
2005 (English)In: Surgery, ISSN 0039-6060, Vol. 137, no 6, p. 632-8Article in journal (Other scientific) Published
Keywords
Adult, Aged, Aged; 80 and over, Cardiovascular Diseases/*complications/*physiopathology/ultrasonography, Cardiovascular System/*physiopathology, Case-Control Studies, Echocardiography, Electrocardiography, Exercise Test, Female, Humans, Hyperparathyroidism/*complications/*surgery, Male, Middle Aged, Parathyroidectomy, Postoperative Period, Research Support; Non-U.S. Gov't, Time Factors
Identifiers
urn:nbn:se:uu:diva-80045 (URN)15933631 (PubMedID)
Available from: 2006-04-21 Created: 2006-04-21 Last updated: 2011-01-11
Zar, N., Garmo, H., Holmberg, L., Rastad, J. & Hellman, P. (2004). Long-term survival of patients with small intestinal carcinoid tumors. World J Surg, 28(11), 1163-1168
Open this publication in new window or tab >>Long-term survival of patients with small intestinal carcinoid tumors
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2004 (English)In: World J Surg, Vol. 28, no 11, p. 1163-1168Article in journal (Refereed) Published
Identifiers
urn:nbn:se:uu:diva-69989 (URN)15490058 (PubMedID)
Available from: 2005-04-13 Created: 2005-04-13 Last updated: 2011-01-12
Stålberg, P., Grimfjärd, P., Santesson, M., Zhou, Y., Lindberg, D., Gobl, A., . . . Skogseid, B. (2004). Transfection of the multiple endocrine neoplastia type 1 gene to a human endocrine pancreatic tumor cell line inhibits cell growth and affects expression of junD, delta-like protein 1/preadipocyte factor-1, proliferating cell nuclear antigen and QM/Jif-1. The journal of clinical endocrinology & metabolism, 5, 2326-2337
Open this publication in new window or tab >>Transfection of the multiple endocrine neoplastia type 1 gene to a human endocrine pancreatic tumor cell line inhibits cell growth and affects expression of junD, delta-like protein 1/preadipocyte factor-1, proliferating cell nuclear antigen and QM/Jif-1
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2004 (English)In: The journal of clinical endocrinology & metabolism, Vol. 5, p. 2326-2337Article in journal (Refereed) Published
Keywords
Aged, Antibody Specificity, Carcinoid Tumor/blood/chemistry, Chromogranins/*blood/chemistry, Endocrine Gland Neoplasms/blood/chemistry, Female, Humans, Male, Middle Aged, Neuroendocrine Tumors/*blood, Pancreatic Neoplasms/blood/chemistry, Peptide Library, Radioimmunoassay/*methods, Research Support; Non-U.S. Gov't
Identifiers
urn:nbn:se:uu:diva-65563 (URN)
Available from: 2005-09-13 Created: 2005-09-13 Last updated: 2011-01-12
Nilsson, I.-L., Aberg, J., Rastad, J. & Lind, L. (2003). Circadian cardiac autonomic nerve dysfunction in primary hyperparathyroidism improves after parathyroidectomy.. Surgery, 134(6), 1013-9; discussion 1019
Open this publication in new window or tab >>Circadian cardiac autonomic nerve dysfunction in primary hyperparathyroidism improves after parathyroidectomy.
2003 (English)In: Surgery, ISSN 0039-6060, Vol. 134, no 6, p. 1013-9; discussion 1019Article in journal (Refereed) Published
Keywords
Aged, Autonomic Nervous System Diseases/etiology/*physiopathology, Blood Pressure, Chronobiology Disorders/etiology/*physiopathology, Female, Heart Diseases/etiology/*physiopathology, Heart Rate/physiology, Humans, Hyperparathyroidism/complications/*physiopathology/surgery, Male, Middle Aged, Parathyroidectomy/*methods, Research Support; Non-U.S. Gov't
Identifiers
urn:nbn:se:uu:diva-73288 (URN)14668735 (PubMedID)
Available from: 2005-06-01 Created: 2005-06-01 Last updated: 2011-01-13
Stålberg, P., Granberg, D., Carling, T., Wilander, E., Eriksson, B., Gobl, A., . . . Skogseid, B. (2003). In Situ RNA-RNA Hybridization of Phospholipase C β3 Shows Lack of Expression in Neuroendocrine Tumours. Anticancer Research, 23(3B), 2227-2232
Open this publication in new window or tab >>In Situ RNA-RNA Hybridization of Phospholipase C β3 Shows Lack of Expression in Neuroendocrine Tumours
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2003 (English)In: Anticancer Research, Vol. 23, no 3B, p. 2227-2232Article in journal (Refereed) Published
Identifiers
urn:nbn:se:uu:diva-70209 (URN)
Available from: 2006-11-09 Created: 2006-11-09 Last updated: 2011-01-13
Nilsson, I., Lundgren, E., Ekbom, A., Ljunghall, S. & Rastad, J. (2003). Management of asymptomatic primary hyperparathyroidism: New North American guidelines discussed from a Swedish perspective. Läkartidningen, 100(47), 3848-3854
Open this publication in new window or tab >>Management of asymptomatic primary hyperparathyroidism: New North American guidelines discussed from a Swedish perspective
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2003 (Swedish)In: Läkartidningen, Vol. 100, no 47, p. 3848-3854Article, review/survey (Other (popular scientific, debate etc.)) Published
Identifiers
urn:nbn:se:uu:diva-68570 (URN)14719237 (PubMedID)
Available from: 2005-03-02 Created: 2005-03-02 Last updated: 2011-01-13
Correa, P., Juhlin, C., Rastad, J., Akerstrom, G., Westin, G. & Carling, T. (2002). Allelic loss in clinically and screening-detected primary hyperparathyroidism. Clin Endocrinol (Oxf), 56(1), 113-117
Open this publication in new window or tab >>Allelic loss in clinically and screening-detected primary hyperparathyroidism
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2002 (English)In: Clin Endocrinol (Oxf), Vol. 56, no 1, p. 113-117Article in journal (Refereed) Published
Identifiers
urn:nbn:se:uu:diva-80861 (URN)
Available from: 2006-06-08 Created: 2006-06-08 Last updated: 2011-01-13
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