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Cheruku, Pradeep
Alternative names
Publications (4 of 4) Show all publications
Cheruku, P., Church, T. & Andersson, P. (2008). Phosphine-Free Cp*Ru(Diamine) Catalysts in the Hydrogenation of Imines. Chemistry - An Asian Journal, 3(8-9), 1390-1394
Open this publication in new window or tab >>Phosphine-Free Cp*Ru(Diamine) Catalysts in the Hydrogenation of Imines
2008 (English)In: Chemistry - An Asian Journal, ISSN (Print)1861-4728.(Online)1861-471X, Vol. 3, no 8-9, p. 1390-1394Article in journal (Refereed) Published
Abstract [en]

We previously reported the phosphine-free Cp*Ru(diamine)-catalyzed hydrogenation of aryl methyl ketones. Herein we present the first report of ruthenium-diamine-catalyzed imine hydrogenation to form amines. The most effective catalyst, I/KOtBu, completely converted several imines to amines at room temperature. The effect of electron-donating and -with- drawing groups on the reaction was investigated using a suitable series of substrates. The asymmetric version of the reaction was studied for two substrates, and the chiral amine products could be obtained in moderate enantiomeric excess.

Keywords
diamine ligands, hydrogenations, imines, ruthenium
National Category
Chemical Sciences
Identifiers
urn:nbn:se:uu:diva-17848 (URN)10.1002/asia.200800182 (DOI)000259119400020 ()
Available from: 2008-09-05 Created: 2008-09-05 Last updated: 2010-06-07Bibliographically approved
Acharya, P., Cheruku, P., Chatterjee, S., Acharya, S. & Chattopadhyaya, J. (2004). Measurement of nucleobase pKa values in model mononucleotides shows RNA-RNA duplexes to be more stable than DNA-DNA duplexes.. J Am Chem Soc, 126(9), 2862-9
Open this publication in new window or tab >>Measurement of nucleobase pKa values in model mononucleotides shows RNA-RNA duplexes to be more stable than DNA-DNA duplexes.
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2004 (English)In: J Am Chem Soc, ISSN 0002-7863, Vol. 126, no 9, p. 2862-9Article in journal (Other scientific) Published
Keywords
DNA/*chemistry, Hydrogen-Ion Concentration, Kinetics, Nucleotides/*chemistry, RNA; Double-Stranded/*chemistry, Research Support; Non-U.S. Gov't, Thermodynamics
Identifiers
urn:nbn:se:uu:diva-73473 (URN)14995203 (PubMedID)
Available from: 2005-06-07 Created: 2005-06-07 Last updated: 2011-01-12
Acharya, S., Barman, J., Cheruku, P., Chatterjee, S., Acharya, P., Isaksson, J. & Chattopadhyaya, J. (2004). Significant pKa perturbation of nucleobases is an intrinsic property of the sequence context in DNA and RNA.. J Am Chem Soc, 126(28), 8674-81
Open this publication in new window or tab >>Significant pKa perturbation of nucleobases is an intrinsic property of the sequence context in DNA and RNA.
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2004 (English)In: J Am Chem Soc, ISSN 0002-7863, Vol. 126, no 28, p. 8674-81Article in journal (Other scientific) Published
Keywords
Base Sequence, DNA; Single-Stranded/*chemistry, Electrostatics, Hydrogen-Ion Concentration, Kinetics, Nuclear Magnetic Resonance; Biomolecular, Nucleic Acid Conformation, Nucleotides/*chemistry, Oligoribonucleotides/chemistry, RNA/*chemistry, Research Support; Non-U.S. Gov't
Identifiers
urn:nbn:se:uu:diva-73471 (URN)15250719 (PubMedID)
Available from: 2005-06-07 Created: 2005-06-07 Last updated: 2011-01-12
Pradeepkumar, P. I., Cheruku, P., Plashkevych, O., Acharya, P., Gohil, S. & Chattopadhyaya, J. (2004). Synthesis, physicochemical and biochemical studies of 1',2'-oxetane constrained adenosine and guanosine modified oligonucleotides, and their comparison with those of the corresponding cytidine and thymidine analogues.. J Am Chem Soc, 126(37), 11484-99
Open this publication in new window or tab >>Synthesis, physicochemical and biochemical studies of 1',2'-oxetane constrained adenosine and guanosine modified oligonucleotides, and their comparison with those of the corresponding cytidine and thymidine analogues.
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2004 (English)In: J Am Chem Soc, ISSN 0002-7863, Vol. 126, no 37, p. 11484-99Article in journal (Other scientific) Published
Keywords
Adenosine/*analogs & derivatives/chemistry, Base Sequence, Circular Dichroism, Cytidine/*analogs & derivatives/chemistry, Deoxyribonuclease I/chemistry/metabolism, Ethers; Cyclic/*chemistry/metabolism, Guanosine/*analogs & derivatives/chemistry, Humans, Kinetics, Models; Molecular, Molecular Sequence Data, Nucleic Acid Conformation, Nucleic Acid Heteroduplexes/chemistry/metabolism, Oligonucleotides/blood/chemical synthesis/*chemistry/metabolism, RNA/chemistry/metabolism, Research Support; Non-U.S. Gov't, Ribonuclease H; Calf Thymus/chemistry/metabolism, Thermodynamics, Thymidine/*analogs & derivatives/chemistry
Identifiers
urn:nbn:se:uu:diva-73480 (URN)15366894 (PubMedID)
Available from: 2005-06-07 Created: 2005-06-07 Last updated: 2011-01-12
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