Logo: to the web site of Uppsala University

uu.sePublications from Uppsala University
Change search
Link to record
Permanent link

Direct link
Alternative names
Publications (10 of 73) Show all publications
Blixt, I., Axelsson, O. & Funkquist, E.-L. (2024). Partners' experiences of breastfeeding: a qualitative evaluation of a breastfeeding support intervention in Sweden. International Breastfeeding Journal, 19, Article ID 6.
Open this publication in new window or tab >>Partners' experiences of breastfeeding: a qualitative evaluation of a breastfeeding support intervention in Sweden
2024 (English)In: International Breastfeeding Journal, ISSN 1746-4358, E-ISSN 1746-4358, Vol. 19, article id 6Article in journal (Refereed) Published
Abstract [en]

Background: The World Health Organization states that women and their families need breastfeeding support from the healthcare system. However, knowledge about the most effective way to involve the partner in breastfeeding is lacking. A qualitative evaluation can provide insight and knowledge about the partner's experiences towards a breastfeeding support intervention and thus contribute to how forthcoming breastfeeding support policies are designed. The aim of this study was to explore partners' experiences regarding breastfeeding while participating in The Breastfeeding Study.

Methods: An exploratory, longitudinal and qualitative design was used. This study was part of The Breastfeeding Study, which took place in Sweden. The intervention was performed in line with the Ten Steps to Successful Breastfeeding. Partners in the in the intervention group (IG) were part of a structured breastfeeding support programme. An individual breastfeeding plan was established in cooperation with the parents-to-be during pregnancy, and the plan was followed up at the child healthcare centre. A purposive sample was recruited from March to December 2021. Interviews and diary entries from IG (n = 8) and control group (CG) (n = 8) during pregnancy and 2 months after birth were analysed by content analysis, in accordance with the COREQ guidelines.

Results: Partners' experiences can be summarised under the main category of 'Striving to be part of the family and important that the family's everyday life was well-functioning'. IG partners experienced that both parents were involved and cooperated in the breastfeeding process and that guidance from healthcare professionals (HCPs) helped them to feel secure. CG partners experienced feeling excluded and not receiving support from HCPs.

Conclusion: Both parents need to be targeted in breastfeeding support policies to meet the support needs. Midwives at antenatal care and child healthcare nurses at the child healthcare centre have important roles to play in providing structured breastfeeding support and a breastfeeding plan. Both IG and CG partners strived to become a part of the infant's life and to make family life work. Midwives should involve both parents in a reflective dialogue on how the partner can be involved, apart from just feeding the infant.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2024
Keywords
Breastfeeding, Experiences, Infant, Intervention, Partner, Support, Qualitative methods
National Category
Nursing
Identifiers
urn:nbn:se:uu:diva-521791 (URN)10.1186/s13006-023-00609-6 (DOI)001145385300001 ()38238818 (PubMedID)
Funder
Uppsala University
Available from: 2024-02-05 Created: 2024-02-05 Last updated: 2024-02-13Bibliographically approved
Ternby, E., Axelsson, O., Georgsson, S. & Ingvoldstad Malmgren, C. (2024). Pregnant women's informational needs prior to decisions about prenatal diagnosis for chromosomal anomalies: A Q methodological study. Prenatal Diagnosis
Open this publication in new window or tab >>Pregnant women's informational needs prior to decisions about prenatal diagnosis for chromosomal anomalies: A Q methodological study
2024 (English)In: Prenatal Diagnosis, ISSN 0197-3851, E-ISSN 1097-0223Article in journal (Refereed) Epub ahead of print
Abstract [en]

Objective

To study pregnant women's subjective viewpoints on what is important when receiving information prior to decision-making regarding prenatal testing for chromosomal anomalies.

Method

Data were collected using Q methodology. During January 2020—October 2021, 45 pregnant women in Sweden completed a 50-item Q sort. Statements regarding what is important when receiving information about prenatal screening and diagnosis were prioritized through ranking in a fixed sorting grid on an 11-point scale, from “most important” to “least important.” Socio-demographics and coping styles were surveyed through questionnaires.

Results

Three groups represented different viewpoints on what pregnant women consider important when receiving information about prenatal screening and diagnosis. Factor 1: Stepwise information and decision-making: viewing information and decision-making as a step-by-step process. Factor 2: Decision-making as a continuous process based on couple autonomy: Striving for an informed decision as a couple about tests, test results and conditions screened. Factor 3: As much information as early as possible—the importance of personal autonomy in decision-making: Prioritizing autonomous decision-making based on non-directive information early in the pregnancy.

Conclusion

This study highlights the complexities involved when providing information. As shown by the differing viewpoints in this study, pregnant women's informational needs differ, making individual and personalized information preferable.

Place, publisher, year, edition, pages
John Wiley & Sons, 2024
Keywords
prenatal diagnosis, informed choice
National Category
Obstetrics, Gynecology and Reproductive Medicine
Research subject
Obstetrics and Gynaecology
Identifiers
urn:nbn:se:uu:diva-519893 (URN)10.1002/pd.6514 (DOI)001134912600001 ()38167810 (PubMedID)
Funder
Sjukvårdsregionala forskningsrådet Mellansverige, RFR-844621
Available from: 2024-02-06 Created: 2024-02-06 Last updated: 2024-02-28Bibliographically approved
Lindström, L., Cnattingius, S., Axelsson, O. & Granfors, M. (2023). Accuracy and precision of sonographic fetal weight estimation in Sweden. Acta Obstetricia et Gynecologica Scandinavica, 102(6), 699-707
Open this publication in new window or tab >>Accuracy and precision of sonographic fetal weight estimation in Sweden
2023 (English)In: Acta Obstetricia et Gynecologica Scandinavica, ISSN 0001-6349, E-ISSN 1600-0412, Vol. 102, no 6, p. 699-707Article in journal (Refereed) Published
Abstract [en]

Introduction: Fetal growth assessment by ultrasound is an essential part of modern obstetric care. The formula by Persson and Weldner for estimated fetal weight (EFW), used in Sweden since decades, has not yet been evaluated. The objective of this study was to evaluate accuracy and precision of the formula by Persson and Weldner, and to compare it to two other formulae using biparietal diameter instead of head circumference.

Material and methods: The study population consisted of 31 521 singleton pregnancies delivered at 22+0 gestational weeks or later, with an ultrasound EFW performed within 2 days before delivery, registered in the Swedish Pregnancy Register between 2014 and 2021. Fetal biometric ultrasound measurements were used to calculate EFW according to the formulae by Persson and Weldner, Hadlock 2 and Shepard. Bland–Altman analysis, systematic error (mean percentage error), random error (standard deviation [SD] of mean percentage error), proportion of weight estimates within ±10% of birthweight, and proportion with underestimated and overestimated weight was calculated. Moreover, calculations were made after stratification into small, appropriate, and large for gestational age (SGA, AGA and LGA), respectively, and gestational age at examination.

Results: For the formula by Persson and Weldner, MPE was −2.7 (SD 8.9) and the proportion of EFW within ±10% from actual birthweight was 76.0%. MPE was largest for fetuses estimated as severe SGA (<3rd percentile, −5.4) and for the most preterm fetuses (<24 weeks, −5.4). For Hadlock 2 and Shepard's formulae, MPE were 3.9 (SD 8.9) and 3.4 (SD 9.7), respectively, and the proportions of EFW within ±10% from actual birthweight were 69.4% and 67.1%, respectively. MPE was largest for fetuses estimated as severe LGA (>97th percentile), 7.6 and 9.4, respectively.

Conclusions: The recommended Swedish formula by Persson and Weldner is generally accurate for fetal weight estimation. The systematic underestimation of EFW and random error is largest in extreme preterm and estimated SGA-fetuses, which is of importance in clinical decision making. The accuracy of EFW with the formula by Persson and Weldner is as good as or better than Hadlock 2 and Shepard's formulae.

Place, publisher, year, edition, pages
John Wiley & SonsWiley, 2023
National Category
Obstetrics, Gynecology and Reproductive Medicine
Research subject
Obstetrics and Gynaecology
Identifiers
urn:nbn:se:uu:diva-499614 (URN)10.1111/aogs.14554 (DOI)000993401800007 ()36964980 (PubMedID)
Available from: 2023-04-03 Created: 2023-04-03 Last updated: 2024-01-15Bibliographically approved
Blixt, I., Rosenblad, A. K., Axelsson, O. & Funkquist, E.-L. (2023). Breastfeeding training improved healthcare professional's self-efficacy to provide evidence-based breastfeeding support: A pre-post intervention study. Midwifery, 125, Article ID 103794.
Open this publication in new window or tab >>Breastfeeding training improved healthcare professional's self-efficacy to provide evidence-based breastfeeding support: A pre-post intervention study
2023 (English)In: Midwifery, ISSN 0266-6138, E-ISSN 1532-3099, Vol. 125, article id 103794Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To describe healthcare professional's (HCP's) perceived self-efficacy in their ability to provide breastfeeding support before and after a breastfeeding training program.

DESIGN: Pre-post intervention study.

SETTING: Antenatal care and child healthcare (CHC) centres in Sweden during 2020.

PARTICIPANTS: An intervention group consisting of 39 HCPs (midwives 51.3%, child healthcare nurses 46.2%) completing a questionnaire at baseline and after intervention, and a control group of 34 HCPs (midwives 61.8%, child healthcare nurses 38.2%) completing a questionnaire at baseline.

INTERVENTION: A breastfeeding training program in line with the Ten Steps to Successful Breastfeeding and WHO recommendations about breastfeeding.

MEASUREMENTS AND FINDINGS: The 11-item Breastfeeding Support Confidence Scale (BSCS) measures HCP's self-efficacy regarding providing breastfeeding support in line with Ten Steps to Successful Breastfeeding and WHO recommendations. The intervention group experienced a significantly increased self-efficacy from pre-intervention to post-intervention for 8 of the 11 BSCS items, with the overall BSCS index score increasing from 36.87 to 39.56 points (p = 0.001). The index score in the intervention group at follow-up was significantly higher than the corresponding score in the control group at baseline (p = 0.025). The intervention group had significantly higher scores at follow-up than the control group at baseline on the questions: "I'm sure that I can help mothers continue to breastfeed even if the infant doesn't follow the growth curve" (p = 0.026) and "I'm sure that I can help mothers continue to breastfeed when the breastfeeding is painful" (p = 0.048).

KEY CONCLUSIONS: The breastfeeding training program improved HCP' self-efficacy to provide evidence-based support to breastfeeding mothers.

IMPLICATIONS FOR PRACTICE: This training program is well suited to implement in clinical practice and follows the Ten Steps to Successful Breastfeeding.

TRIAL REGISTRATION: ACTRN12623000648628.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Breastfeeding, Healthcare professionals, Intervention study, Self-efficacy, Support, Training
National Category
Pediatrics
Identifiers
urn:nbn:se:uu:diva-513106 (URN)10.1016/j.midw.2023.103794 (DOI)001071312900001 ()37660540 (PubMedID)
Available from: 2023-10-03 Created: 2023-10-03 Last updated: 2023-10-18Bibliographically approved
Asp, J., Bergman, L., Lager, S., Axelsson, O., Wikström, A.-K. & Hesselman, S. (2022). Alcohol exposure prior to pregnancy-does hazardous consumption affect placenta- and inflammatory-mediated pregnancy outcomes? A Swedish population-based cohort study. Acta Obstetricia et Gynecologica Scandinavica, 101(12), 1386-1394
Open this publication in new window or tab >>Alcohol exposure prior to pregnancy-does hazardous consumption affect placenta- and inflammatory-mediated pregnancy outcomes? A Swedish population-based cohort study
Show others...
2022 (English)In: Acta Obstetricia et Gynecologica Scandinavica, ISSN 0001-6349, E-ISSN 1600-0412, Vol. 101, no 12, p. 1386-1394Article in journal (Refereed) Published
Abstract [en]

INTRODUCTION: Alcohol consumption during pregnancy is related to severe birth complications such as low birthweight, preterm birth and birth defects. During the last decade, the Alcohol Use Disorders Identification Test (AUDIT) has been used as a screening tool in Swedish maternal healthcare units to identify hazardous, pre-pregnancy alcohol use. However, evaluation of the screening with AUDIT, as well as adverse maternal or neonatal outcomes, has not been assessed at a national level.

MATERIAL AND METHODS: This was a population-based cohort study of 530 458 births from 2013 to 2018 using demographic, reproductive and maternal health data from the Swedish Pregnancy Register. Self-reported alcohol consumption in the year before pregnancy, measured as AUDIT scores, was categorized into moderate (6-13 points) and high-risk (14-40 points) consumption, with low-risk (0-5 points) consumption as the reference group. Associations with pregnancy- and birth outcomes were explored with logistic regressions using generalized estimating equation models, adjusting for maternal and socioeconomic characteristics. Estimates are presented as adjusted odds ratios (aORs) with 95% confidence intervals (CIs).

RESULTS: High-risk and moderate pre-pregnancy alcohol consumption was associated with preeclampsia, preterm birth and birth of an infant small for gestational age (SGA), but these associations were nonsignificant after adjustments. Prior moderate-risk (aOR 1.29, 95% CI 1.17-1.42) and high-risk consumption (aOR 1.62, 95% CI 1.17-2.25) increased the likelihood of intrapartum and neonatal infections.

CONCLUSIONS: Apart from identifying hazardous alcohol consumption prior to pregnancy and the offer of counseling, screening with the AUDIT in early pregnancy indicates a high risk of inflammatory-/placenta-mediated pregnancy and birth outcomes. For most outcomes, AUDIT was not an independent contributor when adjusting for confounding factors. Hazardous alcohol use prior to pregnancy was independently linked to intrapartum and neonatal infections; conditions associated with morbidity and long-term sequalae. These associations may be explained by alcohol-induced changes in the maternal or fetal immune system in early pregnancy or persistent alcohol intake during pregnancy, or may depend on unidentified confounding factors.

Place, publisher, year, edition, pages
John Wiley & Sons, 2022
Keywords
alcohol drinking, placentation, pregnancy, prenatal care, preterm birth
National Category
Obstetrics, Gynecology and Reproductive Medicine
Identifiers
urn:nbn:se:uu:diva-486064 (URN)10.1111/aogs.14451 (DOI)000850819600001 ()36073360 (PubMedID)
Available from: 2022-09-30 Created: 2022-09-30 Last updated: 2023-03-31Bibliographically approved
Akhter, T., Hesselman, S., Lindström, L., Axelsson, O. & Sundström Poromaa, I. (2022). Maternal and Perinatal Outcomes in Singleton Nulliparous Spontaneous Preterm Birth with and without Preterm Premature Rupture of Membranes—A National Population-Based Cohort Study. American Journal of Perinatology
Open this publication in new window or tab >>Maternal and Perinatal Outcomes in Singleton Nulliparous Spontaneous Preterm Birth with and without Preterm Premature Rupture of Membranes—A National Population-Based Cohort Study
Show others...
2022 (English)In: American Journal of Perinatology, ISSN 0735-1631, E-ISSN 1098-8785Article in journal (Refereed) Published
Abstract [en]

Objective Preterm birth (PTB, birth before 37 gestational weeks) is the leading cause of neonatal death and a major challenge for obstetric and neonatal care. About two-thirds of PTBs are spontaneous PTB (sPTB), of which approximately 30% start with preterm premature rupture of membranes (PPROM). The aim of the study was to investigate risk factors and maternal and perinatal outcomes in sPTB with and without PPROM.

Study Design This is a national population-based cohort study including all singleton pregnancies in nulliparous women with spontaneous onset of labor and vaginal births (n = 266,968) registered in the Swedish Medical Birth Register 2005 to 2014. sPTB with PPROM (sPTB-PPROM) and sPTB without PPROM were compared regarding risk factors and maternal and perinatal outcomes. Logistic regression was used to estimate adjusted odds ratios (aORs) with 95% confidence intervals (CIs). Adjustments were made for maternal age, body mass index, country of birth, smoking, chronic hypertension, pregestational and gestational diabetes, and gestational length.

Results sPTB-PPROM (n = 5,037), compared with sPTB without PPROM (n = 8,426), was more common in women with previous spontaneous abortions, prepregnancy urinary tract infections, chronic hypertension, and gestational diabetes and had a higher risk of postpartum endometritis (aOR: 2.78, 95% CI: 1.55–5.00). Infants born to women with sPTB-PPROM had a lower risk of birth asphyxia (aOR: 0.60, 95% CI: 0.43–0.83), respiratory distress syndrome (aOR: 0.86, 95% CI: 0.70–1.00), retinopathy of prematurity (aOR: 0.93, 95% CI: 0.92–0.94), necrotizing enterocolitis (aOR: 0.95, 95% CI: 0.94–0.96), and higher risk of hypoglycemia (aOR: 1.14, 95% CI: 1.01–1.28), and hyperbilirubinemia (aOR: 1.28, 95% CI: 1.19–1.38) compared with infants born to sPTB without PPROM.

Conclusion Our findings of risk factors and distinct differences in adverse outcomes after sPTB-PPROM compared with sPTB without PPROM are of vital importance and might serve as a basis when elaborating programs for the prevention and management of PPROM.

Place, publisher, year, edition, pages
Georg Thieme Verlag KG, 2022
National Category
Obstetrics, Gynecology and Reproductive Medicine
Research subject
Obstetrics and Gynaecology
Identifiers
urn:nbn:se:uu:diva-499613 (URN)10.1055/a-1973-7482 (DOI)000905809000002 ()
Available from: 2023-04-03 Created: 2023-04-03 Last updated: 2023-07-03Bibliographically approved
Gremark, A. & Axelsson, O. (2022). Urogenital Ureaplasma gav invasiv infektion hos immunsupprimerad [Urogenital Ureaplasma urealyticum can cause invasive infection in immunosuppressed patients]. Läkartidningen, 119, Article ID 22038.
Open this publication in new window or tab >>Urogenital Ureaplasma gav invasiv infektion hos immunsupprimerad [Urogenital Ureaplasma urealyticum can cause invasive infection in immunosuppressed patients]
2022 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 119, article id 22038Article in journal (Refereed) Published
Abstract [sv]

Ureaplasma urealyticum (Uu) is a bacterium without a cell wall, which makes it difficult to culture. Uu colonizes the lower genitourinary tract and is transmitted through sexual contact. The presence of Uu is higher in persons with immunosuppressive disease or treatment. Moreover, these persons are at increased risk of developing invasive Uu infections.  We present a case concerning a 47-year-old female with multiple sclerosis treated with Rituximab. She first presented with a urinary tract infection and bartholinitis. Despite treatment with antibiotics and surgical procedures, the infection disseminated and led to intra-abdominal abscesses and empyema. Repeated cultures were negative, which prolonged the time to diagnosis and accurate treatment. Uu was detected with 16S rRNA PCR assays during the course of the disease but was interpreted as non-pathogenic Finally, Uu was suspected as the causing agent, treatment with doxycycline was initiated, and the patient recovered after nine months of disease.

Place, publisher, year, edition, pages
Läkartidningen Förlag AB, 2022
National Category
Infectious Medicine
Identifiers
urn:nbn:se:uu:diva-491912 (URN)35875909 (PubMedID)
Available from: 2022-12-26 Created: 2022-12-26 Last updated: 2023-06-21Bibliographically approved
Valdimarsdottir, R., Wikström, A.-K., Kunovac Kallak, T., Elenis, E., Axelsson, O., Preissl, H., . . . Sundström Poromaa, I. (2021). Pregnancy outcome in women with polycystic ovary syndrome in relation to second-trimester testosterone levels. Reproductive BioMedicine Online, 42(1), 217-225
Open this publication in new window or tab >>Pregnancy outcome in women with polycystic ovary syndrome in relation to second-trimester testosterone levels
Show others...
2021 (English)In: Reproductive BioMedicine Online, ISSN 1472-6483, E-ISSN 1472-6491, Vol. 42, no 1, p. 217-225Article in journal (Refereed) Published
Abstract [en]

RESEARCH QUESTION: Do women with polycystic ovary syndrome (PCOS) have higher testosterone levels during pregnancy and what role does high testosterone play in the development of obstetric complications?

DESIGN: Retrospective cohort study from Uppsala University Hospital, Sweden. The study population consisted of women with PCOS (n = 159) and a comparison group of women without PCOS matched for body mass index (n = 320). Plasma testosterone levels were measured in the early second trimester by liquid chromatography with tandem mass spectrometry, and women with PCOS were grouped into tertiles according to their testosterone levels. Possible associations with obstetric complications, maternal metabolic factors and offspring birth weight were explored by multivariable logistic and linear regression models.

RESULTS: Compared with women who do not have PCOS, women with PCOS had higher total testosterone (median 1.94, interquartile range [IQR] 1.21-2.64 versus 1.41, IQR 0.89-1.97; P < 0.001), and free androgen index (median 0.25, IQR 0.15-0.36 versus 0.18, IQR 0.11-0.28; P < 0.001). Women with PCOS who had the highest levels of testosterone had increased risk for preeclampsia, even when adjusted for age, parity, country of birth and smoking (adjusted OR 6.16, 95% CI 1.82 to 20.91). No association was found between high testosterone in women with PCOS and other obstetric complications.

CONCLUSIONS: Women with PCOS have higher levels of total testosterone and free androgen index during pregnancy than women without PCOS matched for body mass index. Preliminary evidence shows that women with PCOS and the highest maternal testosterone levels in early second trimester had the highest risk of developing preeclampsia. This finding, however, is driven by a limited number of cases and should be interpreted with caution.

Keywords
Birth weight, Maternal metabolic factors, Polycystic ovary syndrome, Pregnancy complications, Testosterone
National Category
Obstetrics, Gynecology and Reproductive Medicine
Identifiers
urn:nbn:se:uu:diva-427146 (URN)10.1016/j.rbmo.2020.09.019 (DOI)000685899500020 ()33077357 (PubMedID)
Funder
Swedish Research Council, 2015-4870
Available from: 2020-12-03 Created: 2020-12-03 Last updated: 2024-03-12Bibliographically approved
Shabana, H., Leidinger, J., Wikström, J. & Axelsson, O. (2021). Prenatal findings and postnatal follow-up of a midline dural sinus malformation. Acta Radiologica Open, 10(4), Article ID 20584601211006315.
Open this publication in new window or tab >>Prenatal findings and postnatal follow-up of a midline dural sinus malformation
2021 (English)In: Acta Radiologica Open, E-ISSN 2058-4601, Vol. 10, no 4, article id 20584601211006315Article in journal (Refereed) Published
Abstract [en]

Dural sinus malformation is a rare condition. We describe a prenatally detected case followed by repeated ultrasound scans and a prenatal magnetic resonance imaging examination. A substantial spontaneous regression was observed, which is associated with a favorable outcome. We believe that our observations, including a long postnatal follow-up, will add to the present knowledge of prenatally detected cases, and thus improve management of the pregnancies as well as our possibilities to counsel the parents-to-be.

Place, publisher, year, edition, pages
Sage PublicationsSAGE PUBLICATIONS LTD, 2021
Keywords
Dural sinus malformation, prenatal diagnosis, ultrasound, magnetic resonance imaging, outcome
National Category
Obstetrics, Gynecology and Reproductive Medicine Radiology, Nuclear Medicine and Medical Imaging
Identifiers
urn:nbn:se:uu:diva-442182 (URN)10.1177/20584601211006315 (DOI)000639157900001 ()33889426 (PubMedID)
Available from: 2021-05-17 Created: 2021-05-17 Last updated: 2024-01-15Bibliographically approved
Hovén, E., Fagerkvist, K., Jahnukainen, K., Ljungman, L., Lähteenmäki, P. M., Axelsson, O., . . . Wettergren, L. (2021). Sexual dysfunction in young adult survivors of childhood cancer - A population-based study. European Journal of Cancer, 154, 147-156
Open this publication in new window or tab >>Sexual dysfunction in young adult survivors of childhood cancer - A population-based study
Show others...
2021 (English)In: European Journal of Cancer, ISSN 0959-8049, E-ISSN 1879-0852, Vol. 154, p. 147-156Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To determine the prevalence of sexual dysfunction and to identify the factors associated with sexual dysfunction in young adult childhood cancer survivors.

METHODS: All survivors of childhood cancer (aged 19-40 years) in Sweden were invited to this population-based study, and 2546 men and women (59%) participated. Sexual function was examined with the PROMIS Sexual Function and Satisfaction Measure. Logistic regression was used to assess the differences between survivors and a general population sample (n = 819) and to identify the factors associated with sexual dysfunction in survivors.

RESULTS: Sexual dysfunction in at least one domain was reported by 57% of female and 35% of male survivors. Among females, dysfunction was most common for Sexual interest (36%), Orgasm - ability (32%) and Vulvar discomfort - labial (19%). Among males, dysfunction was most common for the domains satisfaction with sex life (20%), Sexual interest (14%) and Erectile function (9%). Compared with the general population, male survivors more frequently reported sexual dysfunction in ≥2 domains (OR = 1.67, 95% CI: 1.03-2.71), with an increased likelihood of dysfunction regarding Orgasm - ability (OR = 1.82; 95% CI: 1.01-3.28) and Erectile function (OR = 2.30; 95% CI: 1.18-4.49). Female survivors reported more dysfunction regarding Orgasm - pleasure (9% versus 5%, OR = 1.86; 95% CI: 1.11-3.13). A more intensive cancer treatment, emotional distress and body image disturbance were associated with sexual dysfunction in survivors.

CONCLUSIONS: The findings underscore the need for routine assessment of sexual health in follow-up care of childhood cancer survivors and highlight that those treated with more intensive cancer treatment and who experience concurrent psychological concerns may benefit from targeted screening and interventions.

Place, publisher, year, edition, pages
Elsevier, 2021
Keywords
Childhood cancer, Follow-up care, Sexual dysfunction, Survivors
National Category
Cancer and Oncology
Identifiers
urn:nbn:se:uu:diva-451327 (URN)10.1016/j.ejca.2021.06.014 (DOI)000686049700019 ()34273812 (PubMedID)
Funder
Swedish Cancer Society, CAN 2013/886Swedish Childhood Cancer Foundation, TJ2014-0050Swedish Childhood Cancer Foundation, TJ2019-0045Swedish Childhood Cancer Foundation, PR2014-0177Swedish Childhood Cancer Foundation, PR2016-0075Swedish Childhood Cancer Foundation, PR2017-0037Swedish Research Council, 2017-01530Forte, Swedish Research Council for Health, Working Life and Welfare, 2014-4689
Available from: 2021-08-25 Created: 2021-08-25 Last updated: 2024-01-15Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0003-2989-4303

Search in DiVA

Show all publications