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Öhrvik, John
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Publications (10 of 26) Show all publications
Hedenstierna, G., Tokics, L., Reinius, H., Rothen, H. U., Östberg, E. & Öhrvik, J. (2020). Higher age and obesity limit atelectasis formation during anaesthesia: an analysis of computed tomography data in 243 subjects. British Journal of Anaesthesia, 124(3), 336-344
Open this publication in new window or tab >>Higher age and obesity limit atelectasis formation during anaesthesia: an analysis of computed tomography data in 243 subjects
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2020 (English)In: British Journal of Anaesthesia, ISSN 0007-0912, E-ISSN 1471-6771, Vol. 124, no 3, p. 336-344Article in journal (Refereed) Published
Abstract [en]

Background: General anaesthesia is increasingly common in elderly and obese patients. Greater age and body mass index (BMI) worsen gas exchange. We assessed whether this is related to increasing atelectasis during general anaesthesia.

Methods: This primary analysis included pooled data from previously published studies of 243 subjects aged 18-78 yr, with BMI of 18-52 kg m(-2). The subjects had no clinical signs of cardiopulmonary disease, and they underwent computed tomography (CT) awake and during anaesthesia before surgery after preoxygenation with an inspired oxygen fraction (FIO2) of >0.8, followed by mechanical ventilation with FIO2 of 0.3 or higher with no PEEP. Atelectasis was assessed by CT.

Results: Atelectasis area of up to 39 cm(2) in a transverse scan near the diaphragm was seen in 90% of the subjects during anaesthesia. The log of atelectasis area was related to a quadratic function of (age+age(2)) with the most atelectasis at similar to 50 yr (r(2)=0.08; P<0.001). Log atelectasis area was also related to a broken-line function of the BMI with the knee at 30 kg m(-2) (r(2)=0.06; P<0.001). Greater atelectasis was seen in the subjects receiving FIO2 of 1.0 than FIO2 of 0.3-0.5 (12.8 vs 8.1 cm(2); P<0.001). A multiple regression analysis, including a quadratic function of age, a broken-line function of the BMI, and dichotomised FIO2 (0.3-0.5/1.0) adjusting for ventilatory frequency, strengthened the association (r(2)= 0.23; P<0.001). PaO2 decreased with both age and BMI.

Conclusions: Atelectasis during general anaesthesia increased with age up to 50 yr and decreased beyond that. Atelectasis increased with BMI in normal and overweight patients, but showed no further increase in obese subjects (BMI >= 30 kg m(-2)). Therefore, greater age and obesity appear to limit atelectasis formation during general anaesthesia.

Place, publisher, year, edition, pages
ELSEVIER SCI LTD, 2020
Keywords
age, atelectasis, general anaesthesia, inspired oxygen, mechanical ventilation, obesity, pulmonary complications
National Category
Anesthesiology and Intensive Care
Identifiers
urn:nbn:se:uu:diva-407516 (URN)10.1016/j.bja.2019.11.026 (DOI)000514166800045 ()31918847 (PubMedID)
Available from: 2020-03-25 Created: 2020-03-25 Last updated: 2020-03-25Bibliographically approved
Hedenstierna, G., Tokics, L., Scaramuzzo, G., Rothen, H. U., Edmark, L. & Öhrvik, J. (2019). Oxygenation Impairment during Anesthesia: Influence of Age and Body Weight. Anesthesiology, 131(1), 46-57
Open this publication in new window or tab >>Oxygenation Impairment during Anesthesia: Influence of Age and Body Weight
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2019 (English)In: Anesthesiology, ISSN 0003-3022, E-ISSN 1528-1175, Vol. 131, no 1, p. 46-57Article in journal (Refereed) Published
Abstract [en]

Background: Anesthesia is increasingly common in elderly and overweight patients and prompted the current study to explore mechanisms of age- and weight-dependent worsening of arterial oxygen tension (Pao(2)). Methods: This is a primary analysis of pooled data in patients with (1) American Society of Anesthesiologists (ASA) classification of 1; (2) normal forced vital capacity; (3) preoxygenation with an inspired oxygen fraction (FIO2) more than 0.8 and ventilated with FIO2 0.3 to 0.4; (4) measurements done during anesthesia before surgery. Eighty patients (21 women and 59 men, aged 19 to 69 yr, body mass index up to 30 kg/m(2)) were studied with multiple inert gas elimination technique to assess shunt and perfusion of poorly ventilated regions (low ventilation/perfusion ratio [(V) over dot(A)/Q]) and computed tomography to assess atelectasis. Results: Pao(2) /FIO2 was lower during anesthesia than awake (368; 291 to 470 [median; quartiles] vs. 441; 397 to 462 mm Hg; P = 0.003) and fell with increasing age and body mass index. Log shunt was best related to a quadratic function of age with largest shunt at 45 yr (r(2) = 0.17, P = 0.001). Log shunt was linearly related to body mass index (r(2) = 0.15, P < 0.001). A multiple regression analysis including age, age(2), and body mass index strengthened the association further (r(2) = 0.27). Shunt was highly associated to atelectasis (r(2) = 0.58, P < 0.001). Log low (V) over dot(A)/Q showed a linear relation to age (r(2) = 0.14, P = 0.001). Conclusions: Pao(2)/FIO2 ratio was impaired during anesthesia, and the impairment increased with age and body mass index. Shunt was related to atelectasis and was a more important cause of oxygenation impairment in middle-aged patients, whereas low (V) over dot(A)/Q, likely caused by airway closure, was more important in elderly patients. Shunt but not low (V) over dot(A)/Q increased with increasing body mass index. Thus, increasing age and body mass index impaired gas exchange by different mechanisms during anesthesia.

Place, publisher, year, edition, pages
LIPPINCOTT WILLIAMS & WILKINS, 2019
National Category
Anesthesiology and Intensive Care
Identifiers
urn:nbn:se:uu:diva-393526 (URN)10.1097/ALN.0000000000002693 (DOI)000480727700012 ()31045901 (PubMedID)
Available from: 2019-09-24 Created: 2019-09-24 Last updated: 2019-09-24Bibliographically approved
Widarsson, M., Nohlert, E., Öhrvik, J. & Kerstis, B. (2019). Parental stress and depressive symptoms increase the risk of separation among parents with children less than 11 years of age in Sweden. Scandinavian Journal of Public Health, 47(2), 207-214
Open this publication in new window or tab >>Parental stress and depressive symptoms increase the risk of separation among parents with children less than 11 years of age in Sweden
2019 (English)In: Scandinavian Journal of Public Health, ISSN 1403-4948, E-ISSN 1651-1905, Vol. 47, no 2, p. 207-214Article in journal (Refereed) Published
Abstract [en]

Aims: Parental separations have become more frequent in recent decades. In Western countries, about 25% of children experience parental separation. There is a need to explore the risk factors for separation to give children an optimal childhood. The objective of the present study was to examine parental stress and depressive symptoms during early parenthood and their association with parental separation.

Methods: Four hundred and seven couples completed questionnaires on depressive symptoms for 3 months and parental stress for 18 months after childbirth. Total parental stress and five sub-areas were investigated. To study the separation rate, parents' addresses were recorded 9 to 11 years after childbirth.

Results: Twenty-nine percent of the parents were separated 9 to 11 years after childbirth. Separation was associated with depressive symptoms at 3 months (mothers p = .002, fathers p = .025) and total parental stress at 18 months after childbirth (mothers p = .010, fathers p = .005). The sub-areas of parental stress, Spouse relationship problems (mothers p = <.001, fathers p = .001) and fathers' Social isolation (p = .005), were associated with separation. In multivariable regression analyses of the parents' separation rate 9 to 11 years after childbirth, the only significant predictor was mothers' Spouse relationship problems (p < .001).

Conclusions: The knowledge that parental stress and depressive symptoms are risk factors for separation may simplify professional support for parents in early parenting. Courses for new and expectant parents can use this knowledge to increase parents' awareness.

Keywords
After childbirth, couples, dyadic consensus, parenthood, social isolation, spouse relationship problems
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:uu:diva-381828 (URN)10.1177/1403494817724312 (DOI)000462758700016 ()28803506 (PubMedID)
Available from: 2019-04-17 Created: 2019-04-17 Last updated: 2019-04-17Bibliographically approved
Pettersson, K., Bjerke, K. M., Jahnsen, R., Öhrvik, J. & Rodby-Bousquet, E. (2019). Psychometric evaluation of the Scandinavian version of the caregiver priorities and child health index of life with disabilities. Disability and Rehabilitation, 41(2), 212-218
Open this publication in new window or tab >>Psychometric evaluation of the Scandinavian version of the caregiver priorities and child health index of life with disabilities
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2019 (English)In: Disability and Rehabilitation, ISSN 0963-8288, E-ISSN 1464-5165, Vol. 41, no 2, p. 212-218Article in journal (Refereed) Published
Abstract [en]

Purpose: To examine test-retest reliability and construct validity of the Scandinavian version of the caregiver priorities and child health index of life with disabilities (CPCHILD) questionnaire for children with cerebral palsy (CP).

Methods: Families were recruited in Sweden and Norway and stratified according to the gross motor function classification system levels I-V for children born 2000-2011, mean age 7.9 (SD 3.2). Construct validity based on the first questionnaire (n = 106) was evaluated for known groups, using linear regression analysis. Intraclass correlation coefficient was used to estimate test-retest reliability (n = 64), and Cronbach's alpha was calculated as an indicator of internal consistency.

Results: The questionnaire showed construct validity and the ability to discriminate between levels of gross motor function for the total score and all domain scores (p < 0.05). Test-retest reliability was high with intraclass correlation coefficient of 0.92 for the total score and of 0.72-0.92 for the domain scores. Cronbach's alpha was 0.96 for the total score and 0.83-0.96 for the domain scores.

Conclusions: The Scandinavian version of the CPCHILD for children with CP seems to be a valid and reliable proxy measure for health related quality of life.

Keywords
Cerebral palsy, quality of life, GMFCS, CPCHILD, validity, reliability
National Category
Other Medical Sciences not elsewhere specified
Identifiers
urn:nbn:se:uu:diva-378209 (URN)10.1080/09638288.2017.1378930 (DOI)000458323300011 ()28927310 (PubMedID)
Available from: 2019-03-06 Created: 2019-03-06 Last updated: 2019-03-06Bibliographically approved
Nilsson, G., Hedberg, P., Leppert, J. & Öhrvik, J. (2018). Basic Anthropometric Measures in Acute Myocardial Infarction Patients and Individually Sex- and Age-Matched Controls from the General Population. Journal of Obesity, Article ID 3839482.
Open this publication in new window or tab >>Basic Anthropometric Measures in Acute Myocardial Infarction Patients and Individually Sex- and Age-Matched Controls from the General Population
2018 (English)In: Journal of Obesity, ISSN 2090-0708, E-ISSN 2090-0716, article id 3839482Article in journal (Refereed) Published
Abstract [en]

We compared weight, height, waist and hip circumferences (hip), body mass index (BMI), and waist-to-hip ratio in acute myocardial infarction (MI) patients and individually sex-and age-matched control subjects from the general population in the catchment area of the patients and predicted the risk of MI status by these basic anthropometric measures. The study cohort comprised 748 patients <= 80 years of age with acute MI from a major Swedish cardiac center and their individually sex- and age-matched controls. The analyses were stratified for sex and age (<= 65/>= 66 years). Risk of MI was assessed by conditional logistic regression. A narrow hip in men >66 years was the single strongest risk factor of MI among the anthropometric measures. The combination of hip and weight was particularly efficient in discriminating men >= 66 years with MI from their controls (area under the receiver operating characteristic (AUROC) curve = 0.82). In men <= 65 years, the best combination was hip, BMI, and height (AUROC = 0.79). In women >= 66 years, the best discriminatory model contained only waist-to-hip ratio (AUROC = 0.67), whereas in women <= 65 years, the best combination was hip and BMI (AUROC = 0.68). A narrow hip reasonably reflects small gluteal muscles. This finding might suggest an association between MI and sarcopenia, possibly related to deficiencies in physical activity and nutrition.

National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-371133 (URN)10.1155/2018/3839482 (DOI)000451233500001 ()30533220 (PubMedID)
Note

Corrigendum in: Journal of Obesity, Volume 2018, Article ID 3126805, https://doi.org/10.1155/2018/3126805

Available from: 2018-12-19 Created: 2018-12-19 Last updated: 2019-01-17Bibliographically approved
Doerstling, S., Hedberg, P., Öhrvik, J., Leppert, J. & Henriksen, E. (2018). Growth differentiation factor 15 in a community-based sample: age-dependent reference limits and prognostic impact. Upsala Journal of Medical Sciences, 123(2), 86-93
Open this publication in new window or tab >>Growth differentiation factor 15 in a community-based sample: age-dependent reference limits and prognostic impact
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2018 (English)In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 123, no 2, p. 86-93Article in journal (Refereed) Published
Abstract [en]

Background: Despite the growing body of evidence on growth differentiation factor 15 (GDF-15) reference values for patients with existing cardiovascular disease, limited investigation has been dedicated to characterizing the distribution and prognostic impact of GDF-15 in predominantly healthy populations. Furthermore, current cutoff values for GDF-15 fail to account for the well-documented age-dependence of circulating GDF-15. Methods: From 810 community-dwelling older adults, we selected a group of apparently healthy participants (n = 268). From this sample, circulating GDF-15 was modeled using the generalized additive models for location scale and shape (GAMLSS) to develop age-dependent centile values. Unadjusted and adjusted Cox proportional hazards models were used to assess the association between the derived GDF-15 reference values (expressed as centiles) and all-cause mortality. Results: Smoothed centile curves showed increasing GDF-15 with age in the apparently healthy participants. An approximately three-fold difference was observed between the 95th and 5th GDF-15 centiles across ages. In a median 8.0 years of follow-up, 97 all-cause deaths were observed in 806 participants with eligible values. In unadjusted Cox regression analyses, the hazard ratio (95% CI) for all-cause mortality per 25-unit increase in GDF-15 centile was 1.80 (1.48-2.20) and dichotomized at the 95th centile, >= 95th versus <95th, was 3.04 (1.99-4.65). Age-dependent GDF-15 centiles remained a significant predictor of all-cause mortality in all subsequent adjusted models. Conclusions: Age-dependent GDF-15 centile values developed from a population of apparently healthy older adults are independently predictive of all-cause mortality. Therefore, GDF-15 reference values could be a useful tool for risk-stratification in a clinical setting.

Place, publisher, year, edition, pages
TAYLOR & FRANCIS LTD, 2018
Keywords
All-cause mortality, GDF-15, reference values, survival analysis, protein biomarkers
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-360558 (URN)10.1080/03009734.2018.1460427 (DOI)000438159000003 ()29714603 (PubMedID)
Funder
Swedish Society of Medicine
Available from: 2018-09-14 Created: 2018-09-14 Last updated: 2018-09-14Bibliographically approved
Nohlert, E., Öhrvik, J. & Helgason, A. R. (2018). Self-perceived ability to cope with stress and depressive mood without smoking predicts successful smoking cessation 12 months later in a quitline setting: a secondary analysis of a randomized trial. BMC Public Health, 18, Article ID 1066.
Open this publication in new window or tab >>Self-perceived ability to cope with stress and depressive mood without smoking predicts successful smoking cessation 12 months later in a quitline setting: a secondary analysis of a randomized trial
2018 (English)In: BMC Public Health, ISSN 1471-2458, E-ISSN 1471-2458, Vol. 18, article id 1066Article in journal (Refereed) Published
Abstract [en]

Background: Telephone-based smoking cessation services ('quitlines') are both effective and cost-effective. Knowledge of modifiable baseline factors in real-life settings with heterogeneous participants is essential for the development and improvement of treatment protocols to assist in telephone-based smoking cessation. The aim was to assess if self-perceived abilities to cope measured at baseline, would predict abstinence at the 12-month follow-up at the Swedish National Tobacco Quitline (SNTQ). Methods: The data were retrieved from a previous randomized controlled trial comparing the effectiveness of proactive and reactive service at the SNTQ. Included were 612 clients calling the SNTQ between February 2009 and September 2010. Outcome measures were self-reported point prevalence and 6-month continuous abstinence at the 12-month follow-up. Plausible predictors of smoking cessation were assessed at the first call and in a baseline questionnaire. Self-perceived abilities at baseline were measured by two questions: (1) How likely is it that you will be smoke-free in one year? and (2) How likely are you to be able to handle stress and depressive mood without smoking? The associations between potential predictors and outcome (smoke-free at 12-month follow-up) were assessed by logistic regression analysis. Results: Of the two potential predictors for abstinence at 12-month follow-up, only the perceived ability to handle stress and depressive mood without smoking remained significant in the adjusted analyses (Odds Ratio, OR 1.13, 95% CI 1.00-1.27 for point prevalence and OR 1.16, 95% CI 1.01-1.33 for 6-month continuous abstinence according to intention-to-treat). The overall strongest predictor in the adjusted analyses was smoking status in the week before baseline (OR 3.30, 95% CI 1.79-6.09 for point prevalence and OR 3.97, 95% CI 2.01-7.83 for 6-month continuous abstinence). Conclusions: The perceived ability to handle stress and depressive mood without smoking at baseline predicted the subjects' abstinence at the 12-month follow-up. An assessment of/adjustment for stress and depressive mood coping skills may be appropriate in future smoking cessation treatment and research. The treatment protocol can be tailored to individual differences and needs for optimal support.

Keywords
Depressive mood, Point prevalence, Self-efficacy, Self-perceived abilities, Single-item assessment, 6-month continuous abstinence, Tobacco
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:uu:diva-364201 (URN)10.1186/s12889-018-5973-9 (DOI)000443369000002 ()30153814 (PubMedID)
Funder
Swedish Research CouncilForte, Swedish Research Council for Health, Working Life and WelfareSwedish Heart Lung FoundationThe Swedish Heart and Lung AssociationSwedish Cancer SocietyStockholm County Council
Available from: 2018-10-30 Created: 2018-10-30 Last updated: 2018-10-30Bibliographically approved
Nohlert, E., Öhrvik, J. & Helgason, Á. R. (2018). Self-perceived ability to cope with stress without smoking predicts successful smoking cessation 12 months later in a quitline setting: A Randomized Trial. Paper presented at 17Th World Conference On Tobacco Or Health, 7-9 March 2018, Cape Town, South Africa.. Tobacco Induced Diseases, 16, 118-119
Open this publication in new window or tab >>Self-perceived ability to cope with stress without smoking predicts successful smoking cessation 12 months later in a quitline setting: A Randomized Trial
2018 (English)In: Tobacco Induced Diseases, ISSN 1617-9625, E-ISSN 1617-9625, Vol. 16, p. 118-119Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
European Publishing, 2018
National Category
Substance Abuse
Identifiers
urn:nbn:se:uu:diva-358112 (URN)10.18332/tid/83845 (DOI)000431841800311 ()
Conference
17Th World Conference On Tobacco Or Health, 7-9 March 2018, Cape Town, South Africa.
Note

Supplement: 1

Meeting Abstract: PS-709-4

Available from: 2018-08-24 Created: 2018-08-24 Last updated: 2018-08-24Bibliographically approved
Nilsson, G., Hedberg, P., Jonason, T., Lönnberg, I. & Öhrvik, J. (2007). Heart rate recovery is more strongly associated with the metabolic syndrome, waist circumference, and insulin sensitivity in women than in men among the elderly in the general population. American Heart Journal, 154(3), 460.e1-460.e7
Open this publication in new window or tab >>Heart rate recovery is more strongly associated with the metabolic syndrome, waist circumference, and insulin sensitivity in women than in men among the elderly in the general population
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2007 (English)In: American Heart Journal, ISSN 0002-8703, E-ISSN 1097-6744, Vol. 154, no 3, p. 460.e1-460.e7Article in journal (Refereed) Published
Abstract [en]

Background: Low heart rate recovery (HRR) at exercise test and the metabolic syndrome (MetS) are both predictors of cardiovascular morbidity and mortality. We studied in 75-year-old women and men, representative of the general population, the relationship between (1) HRR and the MetS, (2) HRR and the individual components of the MetS, and (3) HRR and insulin sensitivity. Methods: A cross-sectional study of randomly selected 75-year-olds from a general population was performed (191 women and 194 men). The MetS was defined according to the National Cholesterol Education Program criteria. Heart rate was measured as beats per minute immediately after exercise and at 4 minutes into recovery. Results: Heart rate recovery (median and interquartile range, beat/min) was 48 (37-58) for women and 49 (38-58) for men. Thirty-seven percent of the women and 25% of the men had the MetS. Heart rate recovery was 52 (42-61) for women with the MetS and 42 (31-49) for those without. The corresponding values for men was 50 (39-61) and 47 (35-54); the difference between individuals with and without the MetS was significant for women (P < .001) but not for men (P = .084). The following significant correlation coefficients between HRR and MetS components were found: for women, waist circumference (-0.43, P < .001), high-density lipoprotein cholesterol (0.37, P < .001), insulin sensitivity (-0.37, P < .001), fasting plasma glucose (-0.30, P < .001), and triglycerides (-0.24, P = .001); for men, triglycerides (-0.20, P = .005). The sex disparity in the strength of correlation reached statistical significance for insulin sensitivity (P < .001) and waist circumference (P = .042). Conclusion: Among 75-year-olds, the MetS and related components are more strongly correlated to HRR in women than in men.

Keywords
Aged, Body Weights and Measures, Cross-Sectional Studies, Exercise Test, Female, Heart Rate, Humans, Insulin/*metabolism, Male, Metabolic Syndrome X/*physiopathology
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-16033 (URN)10.1016/j.ahj.2007.06.025 (DOI)000249390100010 ()17719290 (PubMedID)
Available from: 2008-04-08 Created: 2008-04-08 Last updated: 2017-12-08Bibliographically approved
Bartnik, ., Rydén, ., Malmberg, ., Öhrvik, J., Pyörälä, ., Standl, ., . . . Soler-Soler, . (2007). Oral glucose tolerance test is needed for appropriate classification of glucose regulation in patients with coronary artery disease: a report from the Euro Heart Survey on Diabetes and the Heart.. Heart, 93(1), 72-77
Open this publication in new window or tab >>Oral glucose tolerance test is needed for appropriate classification of glucose regulation in patients with coronary artery disease: a report from the Euro Heart Survey on Diabetes and the Heart.
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2007 (English)In: Heart, ISSN 1355-6037, E-ISSN 1468-201X, Vol. 93, no 1, p. 72-77Article in journal (Refereed) Published
Abstract [en]

Background: Patients with coronary artery disease (CAD) and abnormal glucose regulation (AGR) are at high risk for subsequent cardiovascular events, underlining the importance of accurate glucometabolic assessment in clinical practice. Objective: To investigate different methods to identify glucose disturbances among patients with acute and stable coronary heart disease. Methods: Consecutive patients referred to cardiologists were prospectively enrolled at 110 centres in 25 countries (n=4961). Fasting plasma glucose (FPG) and glycaemia 2 h after a 75-g glucose load were requested in patients without known glucose abnormalities (n=3362). Glucose metabolism was classified according to the World Health Organization and American Diabetes Association (ADA; 1997, 2004) criteria as normal, impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or diabetes. Results: Data on FPG and 2-h post-load glycaemia were available for 1867 patients, of whom 870 (47%) had normal glucose regulation, 87 (5%) had IFG, 591 (32%) had IGT and 319 (17%) had diabetes. If classification had been based on the ADA criterion from 1997, the proportion of misclassified (underdiagnosed) patients would have been 39%. The ADA 2004 criterion would have overdiagnosed 8% and underdiagnosed 33% of the patients, resulting in a total misclassification rate of 41%. For ethical concerns and practical reasons, oral glucose tolerance test (OGTT) was not conducted in 1495 of eligible patients. These patients were more often women, had higher age and waist circumference, and were therefore more likely to have AGR than those who were included. A model based on easily available clinical and laboratory variables, including FPG, high-density lipoprotein cholesterol, age and the logarithm of glycated haemoglobin A1c, misclassified 44% of the patients, of whom 18% were overdiagnosed and 26% were underdiagnosed. Conclusion: An OGTT is still the most appropriate method for the clinical assessment of glucometabolic status in patients with coronary heart disease.

Keywords
Aged, Blood Glucose/*metabolism, Body Constitution, Coronary Arteriosclerosis/*blood/complications, Diabetes Mellitus; Type 2/complications/diagnosis, Fasting/blood, Female, Glucose Intolerance, Glucose Metabolism Disorders/complications/*diagnosis, Glucose Tolerance Test/*methods, Health Surveys, Humans, Hyperglycemia/complications/diagnosis, Male, Middle Aged, Prospective Studies
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-10512 (URN)10.1136/hrt.2005.086975 (DOI)16905628 (PubMedID)
Available from: 2007-04-04 Created: 2007-04-04 Last updated: 2017-12-11Bibliographically approved
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