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Publications (10 of 363) Show all publications
Boyle, J. R. & Björck, M. (2024). EJVES 2024 Stability and Development for a Bright Future. European Journal of Vascular and Endovascular Surgery, 67(1), 1-2
Open this publication in new window or tab >>EJVES 2024 Stability and Development for a Bright Future
2024 (English)In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 67, no 1, p. 1-2Article in journal, Editorial material (Other academic) Published
Place, publisher, year, edition, pages
Elsevier, 2024
National Category
Surgery
Identifiers
urn:nbn:se:uu:diva-523977 (URN)10.1016/j.ejvs.2023.11.039 (DOI)001155791100001 ()38102062 (PubMedID)
Available from: 2024-02-27 Created: 2024-02-27 Last updated: 2024-02-27Bibliographically approved
Björck, M., Goncalves, F. B. & Mani, K. (2024). Even the Uncut Diamond Is Valuable. European Journal of Vascular and Endovascular Surgery, 67(5), 857-858
Open this publication in new window or tab >>Even the Uncut Diamond Is Valuable
2024 (English)In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 67, no 5, p. 857-858Article in journal, Editorial material (Other academic) Published
Place, publisher, year, edition, pages
Elsevier, 2024
National Category
Surgery
Identifiers
urn:nbn:se:uu:diva-534414 (URN)10.1016/j.ejvs.2024.04.002 (DOI)001243855100001 ()38599543 (PubMedID)
Available from: 2024-07-08 Created: 2024-07-08 Last updated: 2024-07-08Bibliographically approved
Blaser, A. R., Mandul, M., Björck, M., Acosta, S., Bala, M., Bodnar, Z., . . . Tamme, K. (2024). Incidence, diagnosis, management and outcome of acute mesenteric ischaemia: a prospective, multicentre observational study (AMESI Study). Critical Care, 28(1), Article ID 32.
Open this publication in new window or tab >>Incidence, diagnosis, management and outcome of acute mesenteric ischaemia: a prospective, multicentre observational study (AMESI Study)
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2024 (English)In: Critical Care, ISSN 1364-8535, E-ISSN 1466-609X, Vol. 28, no 1, article id 32Article in journal (Refereed) Published
Abstract [en]

BackgroundThe aim of this multicentre prospective observational study was to identify the incidence, patient characteristics, diagnostic pathway, management and outcome of acute mesenteric ischaemia (AMI).MethodsAll adult patients with clinical suspicion of AMI admitted or transferred to 32 participating hospitals from 06.06.2022 to 05.04.2023 were included. Participants who were subsequently shown not to have AMI or had localized intestinal gangrene due to strangulating bowel obstruction had only baseline and outcome data collected.ResultsAMI occurred in 0.038% of adult admissions in participating acute care hospitals worldwide. From a total of 705 included patients, 418 patients had confirmed AMI. In 69% AMI was the primary reason for admission, while in 31% AMI occurred after having been admitted with another diagnosis. Median time from onset of symptoms to hospital admission in patients admitted due to AMI was 24 h (interquartile range 9-48h) and time from admission to diagnosis was 6h (1-12 h). Occlusive arterial AMI was diagnosed in 231 (55.3%), venous in 73 (17.5%), non-occlusive (NOMI) in 55 (13.2%), other type in 11 (2.6%) and the subtype could not be classified in 48 (11.5%) patients. Surgery was the initial management in 242 (58%) patients, of which 59 (24.4%) underwent revascularization. Endovascular revascularization alone was carried out in 54 (13%), conservative treatment in 76 (18%) and palliative care in 46 (11%) patients. From patients with occlusive arterial AMI, revascularization was undertaken in 104 (45%), with 40 (38%) of them in one site admitting selected patients. Overall in-hospital and 90-day mortality of AMI was 49% and 53.3%, respectively, and among subtypes was lowest for venous AMI (13.7% and 16.4%) and highest for NOMI (72.7% and 74.5%). There was a high variability between participating sites for most variables studied.ConclusionsThe overall incidence of AMI and AMI subtypes varies worldwide, and case ascertainment is challenging. Pre-hospital delay in presentation was greater than delays after arriving at hospital. Surgery without revascularization was the most common management approach. Nearly half of the patients with AMI died during their index hospitalization. Together, these findings suggest a need for greater awareness of AMI, and better guidance in diagnosis and management.Trial registration: NCT05218863 (registered 19.01.2022).ConclusionsThe overall incidence of AMI and AMI subtypes varies worldwide, and case ascertainment is challenging. Pre-hospital delay in presentation was greater than delays after arriving at hospital. Surgery without revascularization was the most common management approach. Nearly half of the patients with AMI died during their index hospitalization. Together, these findings suggest a need for greater awareness of AMI, and better guidance in diagnosis and management.Trial registration: NCT05218863 (registered 19.01.2022).

Place, publisher, year, edition, pages
BioMed Central (BMC), 2024
Keywords
Mesenteric ischaemia, Epidemiology, Diagnosis, Management, Outcome
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-523842 (URN)10.1186/s13054-024-04807-4 (DOI)001155838400002 ()38263058 (PubMedID)
Available from: 2024-02-26 Created: 2024-02-26 Last updated: 2024-02-26Bibliographically approved
Shehab, M., Thorbjörnsen, K., Mani, K., Björck, M. & Wanhainen, A. (2024). Long Term Outcome After EndoVAC Hybrid Repair of Carotid Patch Infection. [Letter to the editor]. European Journal of Vascular and Endovascular Surgery, 67(2), 352-353, Article ID S1078-5884(23)00735-9.
Open this publication in new window or tab >>Long Term Outcome After EndoVAC Hybrid Repair of Carotid Patch Infection.
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2024 (English)In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 67, no 2, p. 352-353, article id S1078-5884(23)00735-9Article in journal, Letter (Other academic) Published
Place, publisher, year, edition, pages
Elsevier, 2024
National Category
Cardiac and Cardiovascular Systems Surgery
Identifiers
urn:nbn:se:uu:diva-514618 (URN)10.1016/j.ejvs.2023.09.004 (DOI)001171380600001 ()37690491 (PubMedID)
Available from: 2023-10-19 Created: 2023-10-19 Last updated: 2024-03-15Bibliographically approved
Earnshaw, J. J. & Björck, M. (2024). Oxygen Supplementation in Acute Limb Ischaemia? [Letter to the editor]. European Journal of Vascular and Endovascular Surgery, 67(4), 693-693
Open this publication in new window or tab >>Oxygen Supplementation in Acute Limb Ischaemia?
2024 (English)In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 67, no 4, p. 693-693Article in journal, Letter (Other academic) Published
Place, publisher, year, edition, pages
Elsevier, 2024
National Category
Sport and Fitness Sciences
Identifiers
urn:nbn:se:uu:diva-534412 (URN)10.1016/j.ejvs.2023.12.004 (DOI)001235345000001 ()38056521 (PubMedID)
Available from: 2024-07-08 Created: 2024-07-08 Last updated: 2024-07-08Bibliographically approved
Reintam Blaser, A., Tamme, K., Starkopf, J., Forbes, A., Murruste, M., Talving, P., . . . Björck, M. (2024). The incidences of acute mesenteric ischaemia vary greatly depending on the population and diagnostic activity [Letter to the editor]. Critical Care, 28(1), Article ID 85.
Open this publication in new window or tab >>The incidences of acute mesenteric ischaemia vary greatly depending on the population and diagnostic activity
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2024 (English)In: Critical Care, ISSN 1364-8535, E-ISSN 1466-609X, Vol. 28, no 1, article id 85Article in journal, Letter (Other academic) Published
Place, publisher, year, edition, pages
BioMed Central (BMC), 2024
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-526121 (URN)10.1186/s13054-024-04870-x (DOI)001187373300001 ()38500182 (PubMedID)
Available from: 2024-04-05 Created: 2024-04-05 Last updated: 2024-04-05Bibliographically approved
Björck, M., Bastos Gonçalves, F. & Mani, K. (2024). Which Direction Does the UK-COMPASS Point To?. European Journal of Vascular and Endovascular Surgery, 67(4), 533-535
Open this publication in new window or tab >>Which Direction Does the UK-COMPASS Point To?
2024 (English)In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 67, no 4, p. 533-535Article in journal, Editorial material (Other academic) Published
Place, publisher, year, edition, pages
Elsevier, 2024
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-531225 (URN)10.1016/j.ejvs.2024.02.042 (DOI)001235820800001 ()38431126 (PubMedID)
Available from: 2024-06-12 Created: 2024-06-12 Last updated: 2024-06-12Bibliographically approved
Lyons, O. T., Behrendt, C.-A. & Björck, M. (2023). Beyond Wires and Knives: What Can We Learn From BEST-CLI and BASIL-2?. European Journal of Vascular and Endovascular Surgery, 66(1), 1-3
Open this publication in new window or tab >>Beyond Wires and Knives: What Can We Learn From BEST-CLI and BASIL-2?
2023 (English)In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 66, no 1, p. 1-3Article in journal, Editorial material (Other academic) Published
Place, publisher, year, edition, pages
Elsevier, 2023
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-510504 (URN)10.1016/j.ejvs.2023.05.032 (DOI)001046685500001 ()37217073 (PubMedID)
Available from: 2023-08-31 Created: 2023-08-31 Last updated: 2023-08-31Bibliographically approved
Reintam Blaser, A., Starkopf, J., Björck, M., Forbes, A., Kase, K., Kiisk, E., . . . Tamme, K. (2023). Diagnostic accuracy of biomarkers to detect acute mesenteric ischaemia in adult patients: a systematic review and meta-analysis. World Journal of Emergency Surgery, 18(1), Article ID 44.
Open this publication in new window or tab >>Diagnostic accuracy of biomarkers to detect acute mesenteric ischaemia in adult patients: a systematic review and meta-analysis
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2023 (English)In: World Journal of Emergency Surgery, E-ISSN 1749-7922, Vol. 18, no 1, article id 44Article, review/survey (Refereed) Published
Abstract [en]

Background

Acute mesenteric ischaemia (AMI) is a disease with different pathophysiological mechanisms, leading to a life-threatening condition that is difficult to diagnose based solely on clinical signs. Despite widely acknowledged need for biomarkers in diagnosis of AMI, a broad systematic review on all studied biomarkers in different types of AMI is currently lacking. The aim of this study was to estimate the diagnostic accuracy of all potential biomarkers of AMI studied in humans.

Methods

A systematic literature search in PubMed, The Cochrane Library, Web of Science and Scopus was conducted in December 2022. Studies assessing potential biomarkers of AMI in (at least 10) adult patients and reporting their diagnostic accuracy were included. Meta-analyses of biomarkers’ sensitivity, specificity, and positive and negative likelihood ratios were conducted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed, and the study quality was assessed with the QUADAS-2 tool.

Results

Seventy-five studies including a total of 9914 patients assessed 18 different biomarkers in serum/plasma and one in urine (each reported in at least two studies), which were included in meta-analyses. None of the biomarkers reached a conclusive level for accurate prediction. The best predictive value overall (all studies with any type and stage of AMI pooled) was observed for Ischaemia-modified albumin (2 studies, sensitivity 94.7 and specificity 90.5), interleukin-6 (n = 4, 96.3 and 82.6), procalcitonin (n = 6, 80.1 and 86.7), and intestinal fatty acid-binding protein (I-FABP) measured in serum (n = 16, 73.9 and 90.5) or in urine (n = 4, 87.9 and 78.9). In assessment of transmural mesenteric ischaemia, urinary I-FABP (n = 2, 92.3 and 85.2) and D-dimer (n = 3, 87.6 and 83.6) showed moderate predictive value. Overall risk of bias was high, mainly because of selected study populations and unclear timings of the biomarker measurements after onset of symptoms. Combinations of biomarkers were rarely studied, not allowing meta-analyses.

Conclusions

None of the studied biomarkers had sufficient sensitivity and specificity to diagnose AMI, although some biomarkers showed moderate predictive accuracy. Future studies should focus on timing of measurements of biomarkers, distinguishing between early stage and transmural necrosis, and between different types of AMI. Additionally, studies on combinations of biomarkers are warranted.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2023
Keywords
Acute mesenteric ischaemia, Biomarker, Diagnostic accuracy
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:uu:diva-512445 (URN)10.1186/s13017-023-00512-9 (DOI)001056351500001 ()37658356 (PubMedID)
Available from: 2023-09-26 Created: 2023-09-26 Last updated: 2024-03-08Bibliographically approved
Modarai, B., Haulon, S., Ainsbury, E., Bockler, D., Vano-Carruana, E., Dawson, J., . . . Schneider, P. (2023). Editor's Choice - European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on Radiation Safety. European Journal of Vascular and Endovascular Surgery, 65(2), 171-222
Open this publication in new window or tab >>Editor's Choice - European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on Radiation Safety
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2023 (English)In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 65, no 2, p. 171-222Article in journal (Refereed) Published
Place, publisher, year, edition, pages
Saunders Elsevier, 2023
National Category
Surgery
Identifiers
urn:nbn:se:uu:diva-506592 (URN)10.1016/j.ejvs.2022.09.005 (DOI)000999990000001 ()36130680 (PubMedID)
Available from: 2023-06-28 Created: 2023-06-28 Last updated: 2023-06-28Bibliographically approved
Projects
Abdominal aortic aneurysm (AAA) Etiology, prevention by screening and therapy [2009-04232_VR]; Uppsala UniversityScreening for abdominal aortic aneurysm, a population-based longitudinal cohort study of elderly men in the county of Uppsala. [2011-00131_VR]; Uppsala UniversityScreening for abdominal aortic aneurysm, a population-based longitudinal cohort study of elderly men in the county of Uppsala [2012-01978_VR]; Uppsala UniversityAbdominal aortic aneurysm: Aetiology, prevention and therapy [2012-02175_VR]; Uppsala University
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0001-6561-9734

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