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Becker, Wulf
Publications (10 of 17) Show all publications
Hansson, S. O., Åman, P., Becker, W., De Koning, D.-J., Lagerkvist, C. J., Larsson, I., . . . Stymne, S. (2018). Breeding for public health: A strategy. Trends in Food Science & Technology, 80, 131-140
Open this publication in new window or tab >>Breeding for public health: A strategy
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2018 (English)In: Trends in Food Science & Technology, ISSN 0924-2244, E-ISSN 1879-3053, Vol. 80, p. 131-140Article, review/survey (Refereed) Published
Abstract [en]

Background Plant and animal breeding can contribute to promote human health by providing new and healthier food products that farmers can produce in an economically viable way and consumers will choose to buy and eat. However, this can only be achieved if breeding makes full use of knowledge about nutrition, consumer behaviour, farming and agricultural economics, A strategy is needed for breeding for public health. Scope and Approach: A multidisciplinary group of researchers has developed a strategy for plant and animal breeding for public health. The group includes experts in plant breeding, animal breeding, food science, nutrition science, clinical nutrition, agricultural economics, consumer research, and ethics. Key Findings and Conclusions: An outline is proposed of a strategy for breeding for public health. It aims at improving public health in both low- and high-income countries. To prevent chronic disease, the highest priority should be to develop healthy variants of traditional food items that can be introduced universally, i.e. completely replace the older, less healthy variants. In particular in low-income countries, food products with enhanced micronutrient content are urgently needed. In all countries, crops with improved fatty acid composition can contribute substantially to improved public health. A reasonable second priority is products that may not be suitable for universal introduction but will expectedly be demanded by large groups of consumers. One example could be diminishing the energy density of traditional foodstuffs by reducing their fat, sugar, and starch content and increasing their dietary fibre content, Changes in the current organization of the market for farm products are needed to encourage the production of healthier foodstuffs.

Place, publisher, year, edition, pages
ELSEVIER SCIENCE LONDON, 2018
Keywords
Animal breeding, Consumers, Energy density, Fat composition, Food choice, Genetic modification, Micronutrients, Nutrition, Obesity, Plant breeding, Public health
National Category
Food Science
Identifiers
urn:nbn:se:uu:diva-369057 (URN)10.1016/j.tifs.2018.07.023 (DOI)000447080600012 ()
Funder
Swedish Research Council, K2015-54X-22081-04-3Mistra - The Swedish Foundation for Strategic Environmental Research
Available from: 2018-12-14 Created: 2018-12-14 Last updated: 2018-12-14Bibliographically approved
Karlsson, M., Olsson, E., Becker, W., Karlström, B., Cederholm, T. & Sjögren, P. (2017). Ability to predict resting energy expenditure with six equations compared to indirect calorimetry in octogenarian men. Experimental Gerontology, 92, 52-55
Open this publication in new window or tab >>Ability to predict resting energy expenditure with six equations compared to indirect calorimetry in octogenarian men
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2017 (English)In: Experimental Gerontology, ISSN 0531-5565, E-ISSN 1873-6815, Vol. 92, p. 52-55Article in journal (Refereed) Published
Abstract [en]

The accuracy of predictive equations for calculating resting energy expenditure (REE) in elderly people has been questioned. Aging is associated with progressive declines in REE, which partly is explained by loss of fat free mass (FFM). Against this background we aimed to identify the most accurate predictive equation for REE in octogenarian men, taking body composition into account and using indirect calorimetry as reference value. REE was measured in 22 men (mean age 82.6 +/- 0.3 years) and compared with six predictive equations: two based on FFM and four based on body weight, height and/or age. FFM was derived from Dual-energy X-ray absorptiometry analyses. Spearman's rank correlations showed a moderate to high positive monotonic correlation (r = 0.62 to 0.79) between measured and calculated REE (all p < 0.005).The mean calculated REE was significantly different from measured REE for all equations except Mifflin-St Jeor. A calculated REE within 10% of measured REE was considered acceptable and the equations of Mifflin-St Jeor, WHO and Harris-Benedict captured 64%, 50% and 45% of the participant, respectively. The Mifflin-St Jeor equation had the lowest root mean square error (138 kcal), followed by the equation by Harris-Benedict (189 kcal) and WHO (220 kcal). The equations from Luhrmann, Henry and Cunningham predicted REE rather poorly in our study subjects, with e.g. <40% of the individuals within 10% of measured REE. Our results indicate that the Mifflin-St Jeor equation (using FFM) is the most accurate equation estimating REE in these octogenarian men. Harris-Benedict or WHO equations are potential alternatives if information on FFM is unavailable, although their accuracy on an individual level is limited.

Place, publisher, year, edition, pages
PERGAMON-ELSEVIER SCIENCE LTD, 2017
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-323020 (URN)10.1016/j.exger.2017.03.013 (DOI)000400530400009 ()28323025 (PubMedID)
Funder
Swedish Research Council, K2010-70X-2141401-3, 2011-2427
Available from: 2017-06-09 Created: 2017-06-09 Last updated: 2018-02-22Bibliographically approved
Järvi, A., Karlström, B., Vessby, B. & Becker, W. (2016). Increased intake of fruits and vegetables in overweight subjects: effects on body weight, body composition, metabolic risk factors and dietary intake. British Journal of Nutrition, 115(10), 1760-1768
Open this publication in new window or tab >>Increased intake of fruits and vegetables in overweight subjects: effects on body weight, body composition, metabolic risk factors and dietary intake
2016 (English)In: British Journal of Nutrition, ISSN 0007-1145, E-ISSN 1475-2662, Vol. 115, no 10, p. 1760-1768Article in journal (Refereed) Published
Abstract [en]

A diet rich in fruits and vegetables has been associated with several health benefits. However, the effects on body weight (BW) and metabolic markers are not fully known. The present study investigated the effects of increased intake of fruits and vegetables in overweight and obese men and women on dietary habits, anthropometry and metabolic control. In a 16-week controlled intervention, thirty-four men and thirty-four women aged 35-65 years (BMI>27 kg/m(2)) were randomised to an intervention (IN) or a reference (RG) group. All participants received general dietary advice, and subjects in the IN group received fruits and vegetables for free, of which >= 500 g had to be eaten daily. BW, waist circumference (WC), sagittal abdominal diameter (SAD), plasma insulin, blood glucose, glycated Hb (HbA1c), serum lipids, blood pressure, plasminogen activator inhibitor-1 activity, urinary isoprostane (iso-8-PGF 2 alpha) and serum carotenoids were measured. Diet was assessed using 3-d weighed food records. In all, thirty subjects in the IN group and thirty-two in the RG group completed the intervention. Intake of fruits and vegetables doubled in the IN group, whereas intake of fruits increased in the RG group. Serum a-and beta-carotene concentrations and intakes of folate and vitamin C increased significantly in the IN group. Energy intake, BW, WC and SAD decreased significantly in both groups. Supine systolic blood pressure decreased significantly in the IN group, with no between-group differences. No significant changes were observed for other metabolic markers. Provision of fruits and vegetables led to substantially increased intakes, with subsequent favourable changes in anthropometry and insulin levels, which tended to be more pronounced in the IN group. The observed improvements may, in combination with improved nutritional markers, have health benefits in the long term.

Keywords
Fruits, Vegetables, Body weight, Food intakes, Metabolic markers
National Category
Health Sciences
Identifiers
urn:nbn:se:uu:diva-302243 (URN)10.1017/S0007114516000970 (DOI)000376675200007 ()26996228 (PubMedID)
External cooperation:
Available from: 2016-09-01 Created: 2016-08-31 Last updated: 2017-11-21Bibliographically approved
Ax, E., Garmo, H., Grundmark, B., Bill-Axelson, A., Holmberg, L., Becker, W., . . . Sjögren, P. (2014). Dietary Patterns and Prostate Cancer Risk: Report from the Population Based ULSAM Cohort Study of Swedish Men. Nutrition and Cancer, 66(1), 77-87
Open this publication in new window or tab >>Dietary Patterns and Prostate Cancer Risk: Report from the Population Based ULSAM Cohort Study of Swedish Men
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2014 (English)In: Nutrition and Cancer, ISSN 0163-5581, E-ISSN 1532-7914, Vol. 66, no 1, p. 77-87Article in journal (Refereed) Published
Abstract [en]

Dietary pattern analyses have increased the possibilities to detect associations between diet and disease. However, studies on dietary pattern and prostate cancer are scarce. Food intake data in the Uppsala Longitudinal Study of Adult Men cohort was determined by 7-day food records. Adherence to a modified Mediterranean Diet Score (mMDS) and a low carbohydrate-high protein (LCHP) score were grouped as low, medium, or high in the whole study population (n = 1,044) and in those identified as adequate reporters of energy intake (n = 566), respectively. Prostate cancer risk was analyzed with Cox proportional hazard regression (median follow-up 13years) and competing risk of death was considered. There were no associations between dietary patterns and prostate cancer (n = 133) in the whole study population. Among adequate reporters the mMDS was not associated with prostate cancer (n = 72). The LCHP score was inversely related to prostate cancer in adequate reporters, adjusted hazard ratios; 0.55 (0.32-0.96) for medium and 0.47 (0.21-1.04) for high compared to low adherent participants (P-for-trend 0.04). Risk relations were not attributable to competing risk of death. In this study, a LCHP diet was associated with lower prostate cancer incidence. Relations emerged in adequate reporters, underscoring the importance of high-quality dietary data.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-217622 (URN)10.1080/01635581.2014.851712 (DOI)000329141100009 ()
Available from: 2014-02-06 Created: 2014-02-04 Last updated: 2018-02-22Bibliographically approved
Ax, E. H., Cederholm, T., Grundmark, B., Bill-Axelson, A., Becker, W., Holmberg, L., . . . Sjögren, P. (2013). Dietary Patterns and prostate cancer risk: a population based cohort study in elderly Swedish men. Paper presented at Joint Annual Meeting of the ASPET/BPS at Experimental Biology (EB), APR 20-24, 2013, Boston, MA. The FASEB Journal, 27(S1), 847.8
Open this publication in new window or tab >>Dietary Patterns and prostate cancer risk: a population based cohort study in elderly Swedish men
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2013 (English)In: The FASEB Journal, ISSN 0892-6638, E-ISSN 1530-6860, Vol. 27, no S1, p. 847.8-Article in journal, Meeting abstract (Other academic) Published
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-203721 (URN)000319883506040 ()
Conference
Joint Annual Meeting of the ASPET/BPS at Experimental Biology (EB), APR 20-24, 2013, Boston, MA
Available from: 2013-07-19 Created: 2013-07-18 Last updated: 2018-02-22Bibliographically approved
Sand, S. & Becker, W. (2012). Assessment of dietary cadmium exposure in Sweden and population health concern including scenario analysis. Food and Chemical Toxicology, 50(3-4), 536-544
Open this publication in new window or tab >>Assessment of dietary cadmium exposure in Sweden and population health concern including scenario analysis
2012 (English)In: Food and Chemical Toxicology, ISSN 0278-6915, E-ISSN 1873-6351, Vol. 50, no 3-4, p. 536-544Article in journal (Refereed) Published
Abstract [en]

The median dietary cadmium exposure for adults in Sweden is around 1 mu g/kg/week and the upper 95th and 99th percentiles are 1.6-1.8 and 1.9-2.2 mu g/kg/week, respectively. Potatoes and wheat flour were the most important food categories, contributing with 40-50% to the exposure. Differences in dietary patterns between high and low exposed individuals were observed; for high exposed individuals, seafood and spinach contributed with an exposure similar to that low exposed individuals received from potatoes and wheat flour. Consequences of differences in methodology used for exposure assessment are discussed. The median exposure is a factor 2 lower compared to that estimated by the European Food Safety Authority (EFSA). It is also a factor 1.4 lower compared to that of the assessment used for development of the EFSA tolerable weekly intake (TWI). The potential importance of this latter fact was addressed by adjusting the present assessment to that used for TWI derivation. While the percentage of the population exceeding the TWI was <1% for the present data, it was around 3% for adjusted data, which is more in line with observations at the level of urinary cadmium. Scenario analysis was also performed to addresses the consequence of increasing/decreasing cadmium occurrence levels.

Keywords
Cadmium, Dietary exposure, Health risk assessment, Uncertainty analysis, Scenario analysis, Tolerable intake
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-174973 (URN)10.1016/j.fct.2011.12.034 (DOI)000303284600014 ()
Available from: 2012-05-31 Created: 2012-05-30 Last updated: 2017-12-07Bibliographically approved
Landström, E., Koivisto Hursti, U.-K., Becker, W. & Magnusson, M. (2007). Use of functional foods among Swedish consumers is related to health-consciousness and perceived effect. British Journal of Nutrition, 98(5), 1058-1069
Open this publication in new window or tab >>Use of functional foods among Swedish consumers is related to health-consciousness and perceived effect
2007 (English)In: British Journal of Nutrition, ISSN 0007-1145, E-ISSN 1475-2662, Vol. 98, no 5, p. 1058-1069Article in journal (Refereed) Published
Abstract [en]

The aim of the present study was to survey attitudes to and use of functional foods and to investigate which demographic variables and attitudes to diet and health predict consumption of functional foods among Swedish consumers. A questionnaire was developed and sent to 2000 randomly selected Swedish citizens aged between 17 and 75 years. A total of 972 (48 %) responded, 53 % were female and 44 % male. Mean age was 45 years. The results revealed that 84 % of respondents were familiar with the concept of functional foods; 83 % had consumed/purchased at least one of the seven functional food products presented in the questionnaire. Of those who had consumed a functional food, 25 % had perceived effect of it. Positive correlations were seen between consumers perceiving a personal reward from eating functional foods, having an interest in natural products and an interest in general health. Consumption/purchase of functional foods was related to beliefs in the effects of the products, having consumed nutraceuticals or dietary supplements, having a diet-related problem personally or in the family, and a high level of education. The characteristic Swedish functional food consumer has a high level of education, is health-conscious and interested in healthy foods and believes in the health effect of functional foods. Thus, factors other than demographics better explain consumption of FF. However, the study population may represent a more health-conscious segment of the Swedish population in general. Additional studies are therefore required to elucidate the attitudes and use of FF in different consumer groups.

Keywords
Vertebrata, Mammalia, Attitude, Health, Consumer, Health food
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-97713 (URN)10.1017/S0007114507761780 (DOI)000250752300025 ()17640416 (PubMedID)
Available from: 2008-11-06 Created: 2008-11-06 Last updated: 2017-12-14Bibliographically approved
Becker, W. (2006). Fetter. In: Näringslära för högskolan (pp. 460). : Liber AB, Stockholm
Open this publication in new window or tab >>Fetter
2006 (Swedish)In: Näringslära för högskolan, Liber AB, Stockholm , 2006, p. 460-Chapter in book (Other (popular scientific, debate etc.))
Place, publisher, year, edition, pages
Liber AB, Stockholm, 2006
Keywords
fett, fettsyror, fettmetabolism, lipoproteiner
National Category
Nutrition and Dietetics Food Science
Identifiers
urn:nbn:se:uu:diva-18447 (URN)91-47-05355-0 (ISBN)
Available from: 2006-12-21 Created: 2006-12-21
Daryani, A., Kocturk, T., Andersson, A., Karlstrom, B., Vessby, B. & Becker, W. (2006). Greater underreporting of dietary intake among immigrant women from Iran and Turkey than in native-Swedish women in Uppsala County. In: 6th International Conference on Dietary Assessment Methods, 27-29 april Köpenhamn, Danmark: Complementary advances in diet and physical activity assessment methodologies.
Open this publication in new window or tab >>Greater underreporting of dietary intake among immigrant women from Iran and Turkey than in native-Swedish women in Uppsala County
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2006 (English)In: 6th International Conference on Dietary Assessment Methods, 27-29 april Köpenhamn, Danmark: Complementary advances in diet and physical activity assessment methodologies, 2006Conference paper, Published paper (Other (popular scientific, debate etc.))
Identifiers
urn:nbn:se:uu:diva-18547 (URN)
Available from: 2006-12-22 Created: 2006-12-22
Håglin, L., Becker, W., Andersson, A. & Hagren, B. (2006). Kost och hälsa i Sverige och världen. In: Näringslära för högskolan (pp. 29-57). : Liber AB, Stockholm
Open this publication in new window or tab >>Kost och hälsa i Sverige och världen
2006 (Swedish)In: Näringslära för högskolan, Liber AB, Stockholm , 2006, p. 29-57Chapter in book (Other (popular scientific, debate etc.))
Place, publisher, year, edition, pages
Liber AB, Stockholm, 2006
Keywords
kost, världfärdssjukdomar, metabola syndromet, över- och undernäring
National Category
Nutrition and Dietetics Food Science
Identifiers
urn:nbn:se:uu:diva-18435 (URN)91-47-05355-0 (ISBN)
Available from: 2007-04-10 Created: 2007-04-10
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