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Eriksson, Mats-Ola
Publications (9 of 9) Show all publications
Eriksson, M.-O. (2013). Aspects on Imaging and Endovascular Treatment of Aortic Dissection and Aneurysm. (Doctoral dissertation). Uppsala: Acta Universitatis Upsaliensis
Open this publication in new window or tab >>Aspects on Imaging and Endovascular Treatment of Aortic Dissection and Aneurysm
2013 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Aortic aneurysm and dissections are potentially life threatening conditions. The advent of endovascular aortic repair (EVAR) and thoracic endovascular aortic repair (TEVAR) has reduced perioperative mortality and morbidity and are now established therapy methods for treatment of aortic disease. Adequate pre- and intraoperative imaging is important for optimal results in endovascular procedures. However, the standard use of CT and angiography may not always be sufficient to provide necessary information required for treatment, and complementary techniques are warranted in selected cases.

TEVAR in acute complicated type B aortic dissections is proven effective in several reports, but long-term clinical outcome and aortic remodelling are still not fully evaluated.

Intravascular phased array imaging (IPAI) was used in patients undergoing EVAR and TEVAR for aortic aneurysm and dissection. The combined information from IPAI and fluoroscopy allowed exact positioning of the stent graft. The colour Doppler function facilitated detection of blood-flow in relevant arteries during and after the procedures, and it also facilitated control of ceased flow in excluded false lumens or aneurysms.

Clinical early and long-term results after TEVAR for acute complicated type B aortic dissection were investigated in all patients treated between 1999 and 2009 at UppsalaUniversityHospital. Results were favourable regarding survival and permanent neurological complications. Long-term follow-up of aortic morphological changes in the same patient group showed overall significant reduction of aortic and false lumen diameters, and an increase of true lumen diameter. Total thrombosis of the false lumen occured more often in patients with DeBakey IIIa aortic dissection, than in IIIb.

In conclusion, IPAI may be a complementary tool to traditional imaging modalities in EVAR and TEVAR in selected cases. Long-term clinical outcome is excellent with favourable aortic remodeling after TEVAR in patients with acute complicated type B aortic dissection.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2013. p. 49
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 850
Keywords
Aneurysms, aorta, stents, ultrasound, colour Doppler, vascular, interventional, aortic dissection, complicated, TEVAR, EVAR, re-intervention, survival, thrombosis, false lumen, aortic remodelling
National Category
Medical and Health Sciences
Research subject
Radiology
Identifiers
urn:nbn:se:uu:diva-187464 (URN)978-91-554-8559-7 (ISBN)
Public defence
2013-02-01, Hedstrandsalen, Akademiska Sjukhuset, Ing 70, Uppsala, 09:15 (Swedish)
Opponent
Supervisors
Available from: 2013-01-10 Created: 2012-12-06 Last updated: 2013-02-11Bibliographically approved
Eriksson, M.-O., Steuer, J., Wanhainen, A., Thelin, S., Eriksson, L.-G. & Nyman, R. (2013). Morphologic Outcome after Endovascular Treatment of Complicated Type B Aortic Dissection. Journal of Vascular and Interventional Radiology, 24(12), 1826-1833
Open this publication in new window or tab >>Morphologic Outcome after Endovascular Treatment of Complicated Type B Aortic Dissection
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2013 (English)In: Journal of Vascular and Interventional Radiology, ISSN 1051-0443, E-ISSN 1535-7732, Vol. 24, no 12, p. 1826-1833Article in journal (Refereed) Published
Abstract [en]

PURPOSE:

To investigate the long-term morphologic changes of the aorta after thoracic endovascular aortic repair (TEVAR) for acute complicated type B aortic dissection and to analyze whether these changes differed between DeBakey class IIIa and IIIb dissections.

MATERIALS AND METHODS:

During the period 1999-2009, 58 patients with acute complicated type B aortic dissection were treated with TEVAR. Seven patients lacked follow-up data, leaving 51 patients-17 patients with DeBakey IIIa aortic dissection and 34 patients with DeBakey IIIa aortic dissection IIIb-for inclusion in the study. Computed tomography scans performed before and after TEVAR were evaluated. Maximum thoracic and abdominal aortic diameters and diameters of the true lumen and false lumen at the level of the maximum aortic diameter in the thorax and abdomen were analyzed as well as degree of thrombosis of the false lumen.

RESULTS:

There was an overall significant reduction of the thoracic aortic diameter, increased true lumen diameter, and reduced false lumen diameter (P < .05). Total thrombosis of the false lumen, with or without reintervention, was seen in 53% of all patients, in 41% primarily and in 12% after reintervention. The IIIa group had a higher degree of total false lumen thrombosis. All patients in the IIIb group had total thrombosis of the false lumen along the stent graft.

CONCLUSIONS:

Long-term follow-up showed favorable aortic remodeling after TEVAR for acute complicated type B aortic dissection. Total thrombosis of the false lumen occurred more often in patients with DeBakey IIIa aortic dissection compared with patients with DeBakey IIIb aortic dissection.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-210382 (URN)10.1016/j.jvir.2013.08.016 (DOI)000327808700010 ()24144537 (PubMedID)
Available from: 2013-11-06 Created: 2013-11-06 Last updated: 2017-12-06Bibliographically approved
Steuer, J., Wanhainen, A., Thelin, S., Nyman, R., Eriksson, M.-O. & Björck, M. (2012). Outcome of endovascular treatment of traumatic aortic transection. Journal of Vascular Surgery, 56(4), 973-978
Open this publication in new window or tab >>Outcome of endovascular treatment of traumatic aortic transection
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2012 (English)In: Journal of Vascular Surgery, ISSN 0741-5214, E-ISSN 1097-6809, Vol. 56, no 4, p. 973-978Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE:

The purpose of this study was to analyze our experience of thoracic endovascular aortic repair (TEVAR) in patients with traumatic aortic transection.

METHODS:

This was a single-center consecutive case series that was conducted at the Uppsala University Hospital, Tertiary Referral Center. There were a total of 17 consecutive patients undergoing TEVAR for traumatic thoracic aortic transection. All patients undergoing TEVAR for aortic transection were registered prospectively and their medical records were reviewed regarding technical details, mechanism of injury, and concomitant injuries. Long-term outcome was analyzed with respect to need for reintervention and survival.

RESULTS:

Between 2001 and 2010, 17 patients underwent TEVAR for traumatic aortic injury. Median age was 42 years (range, 18-77 years), and 15 of 17 patients (88%) were men. Fourteen patients had been involved in motor vehicle accidents, two had fallen from heights, and one fell off a bicycle on a slope. In all cases, the aortic injury was located in the proximity of the origin of the left subclavian artery. All patients had concomitant injuries. In all patients, a single stent graft was sufficient to exclude the injured part of the aorta. The median cover length was 120 mm (range, 100-200 mm). In-hospital mortality was 24% (4 of 17 patients). One patient died perioperatively and three postoperatively, two from brain injuries and one from multiorgan failure. After a median follow-up of 36 months (range, 10-98 months), three patients underwent reintervention (18%), each patient only once; one for a type-I endoleak, and two for pseudocoarctation secondary to stent graft infolding. Two were treated endovascularly, and one had a stent graft explantation.

CONCLUSIONS:

Endovascular repair allows rapid and minimally invasive therapy in patients with traumatic aortic injury with good technical results. The outcome is highly dependent on the severity of other concurrent injuries.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-177105 (URN)10.1016/j.jvs.2012.03.259 (DOI)000309512300012 ()22608791 (PubMedID)
Available from: 2012-07-04 Created: 2012-07-04 Last updated: 2017-12-07Bibliographically approved
Steuer, J., Eriksson, M.-O., Nyman, R., Björck, M. & Wanhainen, A. (2011). Early and Long-term Outcome after Thoracic Endovascular Aortic Repair (TEVAR) for Acute Complicated Type B Aortic Dissection. European Journal of Vascular and Endovascular Surgery, 41(3), 318-323
Open this publication in new window or tab >>Early and Long-term Outcome after Thoracic Endovascular Aortic Repair (TEVAR) for Acute Complicated Type B Aortic Dissection
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2011 (English)In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 41, no 3, p. 318-323Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: The study aimed to investigate early and long-term outcome of thoracic endovascular aortic repair (TEVAR) for acute complicated type B dissection. DESIGN: This was a retrospective, single-centre, consecutive case series. MATERIALS AND METHODS: During the period 1999-2009, TEVAR was carried out in 50 patients with non-traumatic acute complicated type B dissection, and in another 10 patients with acute complications, including rupture, end-organ ischaemia and acute dilatation during the primary hospitalisation, but >14 days after onset of symptoms. Thus, in total, 60 patients were included; 22 with a DeBakey type IIIa dissection and 38 with a type IIIb; median age was 67 years. Early (30-day) and long-term (5-year) survival, re-intervention rate and complications were recorded until 1 July 2010. RESULTS: Within 30 days, two (3%) deaths, one (2%) paraplegia and three (5%) strokes were observed. Five-year survival was 87% and freedom from re-intervention at 5 years was 65%. CONCLUSIONS: In patients with acute complicated type B aortic dissection, TEVAR can be performed with excellent early and long-term survival, whereas morbidity and long-term durability must be further elucidated.

Keywords
Aortic dissection-acute, Aortic dissection-complicated, Endovascular repair, Re-intervention, Survival, TEVAR
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-140800 (URN)10.1016/j.ejvs.2010.11.024 (DOI)000288728400004 ()21194985 (PubMedID)
Available from: 2011-01-10 Created: 2011-01-10 Last updated: 2017-12-11Bibliographically approved
Eriksson, M.-O. & Nyman, R. (2011). The value of intravascular phased-array imaging in endovascular treatment of thoracic aortic pathology. Acta Radiologica, 52(3), 285-290
Open this publication in new window or tab >>The value of intravascular phased-array imaging in endovascular treatment of thoracic aortic pathology
2011 (English)In: Acta Radiologica, ISSN 0284-1851, E-ISSN 1600-0455, Vol. 52, no 3, p. 285-290Article in journal (Refereed) Published
Abstract [en]

Background Careful pre-, intra- and postoperative diagnostics in endovascular treatment of thoracic aortic pathology is crucial for a favourable outcome. Computer tomography (CT) and digitally subtracted angiography (DSA) do not always provide sufficient diagnostic information. Purpose To report our primary experiences of using intraluminal phased-array imaging (IPAI) as an additive tool for diagnostics and endovascular treatment of thoracic aortic pathology. Material and Methods Eleven patients, nine men and two women (mean age 60, range 45) were examined intraoperatively with IPAI in stentgraft procedures of thoracic aortic pathology. Results IPAI could detect and visualize the entries and re-entries in the intima. Aortic branch vessels could be visualized for patency both during and immediately after stentgraft deployment. It was also possible to detect ceased blood flow in the false lumen or aneurysmal sac after stentgraft deployment. Conclusion IPAI is a helpful tool for diagnostics and for guiding stentgraft placing in the treatment of thoracic aortic pathology.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-152741 (URN)10.1258/ar.2010.100040 (DOI)21498364 (PubMedID)
Available from: 2011-04-29 Created: 2011-04-29 Last updated: 2017-12-11Bibliographically approved
Eriksson, M.-O., Wanhainen, A. & Nyman, R. (2009). Intravascular Ultrasound with a Vector Phased-Array Probe (AcuNav) Is Feasible in Endovascular Abdominal Aortic Aneurysm Repair. Acta Radiologica, 50(8), 870-875
Open this publication in new window or tab >>Intravascular Ultrasound with a Vector Phased-Array Probe (AcuNav) Is Feasible in Endovascular Abdominal Aortic Aneurysm Repair
2009 (English)In: Acta Radiologica, ISSN 0284-1851, E-ISSN 1600-0455, Vol. 50, no 8, p. 870-875Article in journal (Refereed) Published
Abstract [en]

Background: The ideal imaging method for endovascular aneurysm repair (EVAR) should provide all data regarding diagnosis, measurements, and guiding of stent-graft deployment. Contrast-enhanced computed tomography (CT) is used for preoperative EVAR planning, together with intraoperative angiography. However, the administered contrast volume might result in contrast-induced nephropathy (CIN). Purpose: To develop a technique for aortic measurements, vessel wall evaluation, and stent-graft positioning by using a vector phased-array intravascular ultrasound probe with color Doppler function (AcuNav) in elective EVAR. Material and Methods: Thirteen elective EVAR patients were included. AcuNav was compared to pre- and postoperative CT examinations, perioperative angiography, and postoperative duplex. Results: Measurements for stent-graft sizing were easily obtained and facilitated by the color Doppler function and corresponded well with CT and angiography. The combined information from AcuNav and fluoroscopy provided exact positioning of the stent graft. An aortic placement of the probe provided superior imaging results compared to an inferior vena cava approach. Detection of endoleak was found to be difficult. No complications were registered. Conclusion: The use of AcuNav combined with fluoroscopy in EVAR was found to be safe, effective, and feasible in planning and guiding EVAR procedures. Best results were seen with the probe placed in the artery. AcuNav might be used to replace contrast-enhanced CT and angiography, hence reducing the risk of CIN, especially in high-risk patients.

Keywords
aneurysms, aorta, stents, ultrasound, vascular
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-110130 (URN)10.1080/02841850902912010 (DOI)000270459200006 ()19452296 (PubMedID)
Available from: 2009-11-04 Created: 2009-11-04 Last updated: 2017-12-12Bibliographically approved
Wanhainen, A., Nyman, R., Eriksson, M.-O. & Björck, M. (2008). First report of a late type III endoleak from fabric tears of a Zenith stent graft. Journal of vascular surgery, 48(3), 723-726
Open this publication in new window or tab >>First report of a late type III endoleak from fabric tears of a Zenith stent graft
2008 (English)In: Journal of vascular surgery, ISSN 0741-5214, Vol. 48, no 3, p. 723-726Article in journal (Refereed) Published
Abstract [en]

We report a case of a late type III endoleak from a hole in the fabric of the main body of a Zenith bifurcated endograft 7 years after implantation. Abdominal pain and a rapidly expanding aneurysm were eventually followed by rupture. The defect was detected at open surgery, whereas no evidence of endoleak was found at preoperative computed tomography (CT) or angiogram. The defect was repaired by a relining procedure with an Excluder stent graft. The patient, however, died 3 weeks after admission.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-105084 (URN)10.1016/j.jvs.2008.03.047 (DOI)000258837500031 ()18727968 (PubMedID)
Available from: 2009-06-01 Created: 2009-06-01 Last updated: 2012-03-07Bibliographically approved
Ljungman, C., Wanhainen, A., Kragsterman, B., Nyman, R., Eriksson, L.-G. & Eriksson, M.-O. (2008). Propositions for refinement of the hybrid surgical technique for treatment of thoraco-abdominal aortic aneurysm. Scandinavian Journal of Surgery, 97(2), 174-177
Open this publication in new window or tab >>Propositions for refinement of the hybrid surgical technique for treatment of thoraco-abdominal aortic aneurysm
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2008 (English)In: Scandinavian Journal of Surgery, ISSN 1457-4969, E-ISSN 1799-7267, Vol. 97, no 2, p. 174-177Article, review/survey (Refereed) Published
Abstract [en]

Traditional open repair of thoraco-abdominal aortic aneurysms Crawford type II-IV carries a high perioperative risk and mortality. The hybrid technique for combined surgical and endovascular treatment offers an interesting alternative with reduced risk of paraparesis and possibly a reduced mortality rate. Propositions for refinement of this approach are outlined based on a single centre experience.

Keywords
Aortic aneurysm, Crawford type II, Endovascular surgery, Hybride technique, Open surgery, Thoraco-abdominal hybrid repair
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-88024 (URN)000256057700021 ()18575038 (PubMedID)
Available from: 2009-01-19 Created: 2009-01-19 Last updated: 2017-12-14Bibliographically approved
Nyman, R. & Eriksson, M.-O. (2008). The future of imaging in the management of abdominal aortic aneurysm. Scandinavian Journal of Surgery, 97(2), 110-115
Open this publication in new window or tab >>The future of imaging in the management of abdominal aortic aneurysm
2008 (English)In: Scandinavian Journal of Surgery, ISSN 1457-4969, E-ISSN 1799-7267, Vol. 97, no 2, p. 110-115Article, review/survey (Refereed) Published
Abstract [en]

The development of endovascular techniques depends on the concomitant development of imaging techniques. Imaging with ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MR) is evolving at rapid pace. Angiography has largely been replaced by these techniques as a diagnostic tool in the clinical setting. New methods, e.g., rotational angiography and intravascular ultrasound, will play an important role in endovascular treatment of vascular disease. It is necessary to have easy access to ultrasonography, CT and MR images in future hybrid angiographic/surgical suites and the operator must be able to do advanced immediate reconstructions in a sterile environment. The combined use of advanced imaging, open and endovascular techniques will further improve the treatment of vascular disease in the future.

Keywords
Abdominal aortic aneurysm, EVAR, Hybrid angiographic/surgical suites, Imaging, Intravascular ultrasound, Rotational angiography
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-105097 (URN)000256057700006 ()18575025 (PubMedID)
Available from: 2009-06-01 Created: 2009-06-01 Last updated: 2017-12-13Bibliographically approved
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