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Sahlman, Tobias
Publications (3 of 3) Show all publications
Saether, S. A., Fiske, P., Kålås, J., Kuresoo, A., Luigujoe, L., Piertney, S., . . . Höglund, J. (2007). Inferring local adaptation from QST-FST comparisons: neutral genetic and quantitative trait variation in European populations of great snipe. Journal of Evolutionary Biology, 20(4), 1563-1576
Open this publication in new window or tab >>Inferring local adaptation from QST-FST comparisons: neutral genetic and quantitative trait variation in European populations of great snipe
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2007 (English)In: Journal of Evolutionary Biology, ISSN 1010-061X, E-ISSN 1420-9101, Vol. 20, no 4, p. 1563-1576Article in journal (Refereed) Published
Abstract [en]

We applied a phenotypic QST (PST) vs. FST approach to study spatial variation in selection among great snipe (Gallinago media) populations in two regions of northern Europe. Morphological divergence between regions was high despite low differentiation in selectively neutral genetic markers, whereas populations within regions showed very little neutral divergence and trait differentiation. QST > FST was robust against altering assumptions about the additive genetic proportions of variance components. The homogenizing effect of gene flow (or a short time available for neutral divergence) has apparently been effectively counterbalanced by differential natural selection, although one trait showed some evidence of being under uniform stabilizing selection. Neutral markers can hence be misleading for identifying evolutionary significant units, and adopting the PST–FST approach might therefore be valuable when common garden experiments is not an option. We discuss the statistical difficulties of documenting uniform selection as opposed to divergent selection, and the need for estimating measurement error. Instead of only comparing overall QST and FST values, we advocate the use of partial matrix permutation tests to analyse pairwise QST differences among populations, while statistically controlling for neutral differentiation.

Keywords
conservation units, divergent selection, local adaptation, microsatellite primers, partial Mantel test, Q ST, repeatability as heritability
National Category
Biological Sciences
Identifiers
urn:nbn:se:uu:diva-96529 (URN)10.1111/j.1420-9101.2007.01328.x (DOI)000248177600030 ()17584249 (PubMedID)
Available from: 2007-11-15 Created: 2007-11-15 Last updated: 2017-12-14Bibliographically approved
Ekblom, R., Sæther, S. A., Jacobsson, P., Fiske, P., Sahlman, T., Grahn, M., . . . Höglund, J. (2007). Spatial pattern of MHC class II variation in the great snipe (Gallinago media). Molecular Ecology, 16(7), 1439-1451
Open this publication in new window or tab >>Spatial pattern of MHC class II variation in the great snipe (Gallinago media)
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2007 (English)In: Molecular Ecology, ISSN 0962-1083, E-ISSN 1365-294X, Vol. 16, no 7, p. 1439-1451Article in journal (Refereed) Published
Abstract [en]

The genes of the major histocompatibility complex (MHC) code for proteins involved in antigen recognition and triggering of the adaptive immune response, and are therefore likely to be under selection from parasites. These selection regimes may vary in space and time. Here we report a strong geographical structure in MHC class II B genes of a migrating bird, the great snipe (Gallinago media). Genetic differentiation in the MHC between two ecologically distinct distributional regions (Scandinavian mountain populations vs. East European lowland populations) was still present after statistically controlling for the effect of selectively neutral variation (microsatellites) using partial Mantel tests. This suggests a role for selection in generating this spatial structure and that it represents local adaptation to different environments. Differentiation between populations within the two regions was negligible. Overall, we found a high number of MHC alleles (50, from 175 individuals). This, together with a tendency for a higher rate of nonsynonymous than synonymous substitutions in the peptide binding sites, and high Tajima's D in certain regions of the gene, suggests a history of balancing selection. MHC variation is often thought to be maintained by some form of balancing selection, but the nature of this selection remains unclear. Our results support the hypothesis that spatial variation in selection regimes contributes to the high polymorphism.

Keywords
balancing selection, DGGE, F ST, local adaptation, MHC Class II B, partial Mantel test
National Category
Biological Sciences
Identifiers
urn:nbn:se:uu:diva-92220 (URN)10.1111/j.1365-294X.2007.03281.x (DOI)000245162700011 ()17391268 (PubMedID)
Available from: 2004-10-22 Created: 2004-10-22 Last updated: 2017-12-14Bibliographically approved
Dowling, D., Antos, M. & Sahlman, T. (2003). Dispersal and recruitment of juvenile Red-capped robins, Petroica goodenovii. Emu: Austral Ornithology, 103, 199-205
Open this publication in new window or tab >>Dispersal and recruitment of juvenile Red-capped robins, Petroica goodenovii
2003 (English)In: Emu: Austral Ornithology, ISSN 0158-4197, Vol. 103, p. 199-205Article in journal (Refereed) Published
Identifiers
urn:nbn:se:uu:diva-66781 (URN)
Available from: 2007-06-21 Created: 2007-06-21 Last updated: 2011-01-13
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