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Ax, A.-K., Husberg, M., Johansson, B., Demmelmaier, I., Berntsen, S., Sjövall, K., . . . Davidson, T. (2023). Cost-effectiveness of different exercise intensities during oncological treatment in the Phys-Can RCT. Acta Oncologica, 62(4), 414-421
Open this publication in new window or tab >>Cost-effectiveness of different exercise intensities during oncological treatment in the Phys-Can RCT
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2023 (English)In: Acta Oncologica, ISSN 0284-186X, E-ISSN 1651-226X, Vol. 62, no 4, p. 414-421Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Cost-effectiveness is important in the prioritisation between interventions in health care. Exercise is cost-effective compared to usual care during oncological treatment; however, the significance of exercise intensity to the cost-effectiveness is unclear. In the present study, we aimed to evaluate the long-term cost-effectiveness of the randomised controlled trial Phys-Can, a six-month exercise programme of high (HI) or low-to-moderate intensity (LMI) during (neo)adjuvant oncological treatment.

METHODS: A cost-effectiveness analysis was performed, based on 189 participants with breast, colorectal, or prostate cancer (HI: n = 99 and LMI: n = 90) from the Phys-Can RCT in Sweden. Costs were estimated from a societal perspective, and included cost of the exercise intervention, health care utilisation and productivity loss. Health outcomes were assessed as quality-adjusted life-years (QALYs), using EQ-5D-5L at baseline, post intervention and 12 months after the completion of the intervention.

RESULTS: At 12-month follow-up after the intervention, the total cost per participant did not differ significantly between HI (€27,314) and LMI exercise (€29,788). There was no significant difference in health outcome between the intensity groups. On average HI generated 1.190 QALYs and LMI 1.185 QALYs. The mean incremental cost-effectiveness ratio indicated that HI was cost effective compared with LMI, but the uncertainty was large.

CONCLUSIONS: We conclude that HI and LMI exercise have similar costs and effects during oncological treatment. Hence, based on cost-effectiveness, we suggest that decision makers and clinicians can consider implementing both HI and LMI exercise programmes and recommend either intensity to the patients with cancer during oncological treatment to facilitate improvement of health.

Place, publisher, year, edition, pages
Taylor & Francis, 2023
Keywords
Cancer, cost-effectiveness, exercise, health
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:uu:diva-501994 (URN)10.1080/0284186X.2023.2200149 (DOI)000971022300001 ()37074759 (PubMedID)
Available from: 2023-05-17 Created: 2023-05-17 Last updated: 2024-03-18Bibliographically approved
Sjövall, K., Langegård, U., Fransson, P., Nevo-Ohlsson, E., Kristensen, I., Ahlberg, K. & Johansson, B. (2023). Evaluating patient reported outcomes and experiences in a novel proton beam clinic - challenges, activities, and outcomes of the ProtonCare project. BMC Cancer, 23, Article ID 132.
Open this publication in new window or tab >>Evaluating patient reported outcomes and experiences in a novel proton beam clinic - challenges, activities, and outcomes of the ProtonCare project
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2023 (English)In: BMC Cancer, ISSN 1471-2407, E-ISSN 1471-2407, Vol. 23, article id 132Article in journal (Refereed) Published
Abstract [en]

Background: The ProtonCare Study Group (PCSG) was formed with the purpose to develop and implement a framework for evaluation of proton beam therapy (PBT) and the related care at a novel clinic (Skandionkliniken), based on patient reported data.

Method: A logic model framework was used to describe the process of development and implementation of a structured plan for evaluation of PBT for all diagnoses based on patient reported data. After the mission for the project was determined, meetings with networks and stakeholders were facilitated by PCSG to identify assumptions, resources, challenges, activities, outputs, outcomes, and outcome indicators.

Result: This paper presents the challenges and accomplishments PCSG made so far. We describe required resources, activities, and accomplished results. The long-term outcomes that were outlined as a result of the process are two; 1) Improved knowledge about health outcomes of patients that are considered for PBT and 2) The findings will serve as a base for clinical decisions when patients are referred for PBT.

Conclusion: Using the logical model framework proved useful in planning and managing the ProtonCare project. As a result, the work of PCSG has so far resulted in long-lasting outcomes that creates a base for future evaluation of patients' perspective in radiotherapy treatment in general and in PBT especially. Our experiences can be useful for other research groups facing similar challenges. Continuing research on patients ' perspective is a central part in ongoing and future research. Collaboration, cooperation, and coordination between research groups/networks from different disciplines are a significant part of the work aiming to determine the more precise role of PBT in future treatment options.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2023
Keywords
Research program planning, Proton beam therapy, Patient reported outcomes, Cancer nursing, Radiotherapy
National Category
Cancer and Oncology
Identifiers
urn:nbn:se:uu:diva-498168 (URN)10.1186/s12885-023-10586-y (DOI)000931458600003 ()36759789 (PubMedID)
Note

De två sista författarna delar sistaförfattarskapet.

Available from: 2023-03-10 Created: 2023-03-10 Last updated: 2023-03-10Bibliographically approved
Igelström, H., Carlsson, M., Hauffman, A., von Essen, L., Grönqvist, H., Johansson, B. & Olsson, E. M. G. (2023). Long-term effects on depression and anxiety of an internet-based stepped care intervention for patients with cancer and symptoms of depression and anxiety: The U-CARE AdultCan trial. Internet Interventions, 32, Article ID 100625.
Open this publication in new window or tab >>Long-term effects on depression and anxiety of an internet-based stepped care intervention for patients with cancer and symptoms of depression and anxiety: The U-CARE AdultCan trial
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2023 (English)In: Internet Interventions, ISSN 2214-7829, Vol. 32, article id 100625Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Cancer is a serious disease that commonly causes significant psychological distress. The internet-based intervention (iCAN-DO), utilizing a stepped care approach for the treatment of anxiety and depression in individuals with cancer, has been shown to have favorable results for symptoms of depression at the primary endpoint, 10 months after randomization compared to standard care (SC). The aim of the present study was to evaluate the long-term effects of the intervention 18 and 24 months after randomization.

METHODS: Patients with breast, colorectal, or prostate cancer and a score > 7 on either of the Hospital Anxiety and Depression Scale (HADS) subscales (n = 245) were recruited to the study in conjunction with a regular hospital visit. They were randomized to access to the stepwise iCAN-DO intervention for 24 months or to SC. Step 1 of the intervention comprised psycho-educative online material. In Step 2, internet-based cognitive-behavioral therapy with individual online support from a therapist was added. Step 2 was offered to those who reported persistent anxiety or depression symptoms (>7 on HADS), also at 1, 4, and/or 7 months after randomization. Missing data were imputed using the last rank carried forward method and used for the main analyses according to the intention-to-treat approach. Effects sizes (Cohen's d), and minimally clinically important difference (MCID) were calculated. Linear mixed models were used to analyze intervention effects over time.

RESULTS: Symptoms of depression decreased significantly (p < 0.05) in the iCAN-DO group compared with the SC group from baseline to 18 months (d = 0.29), but not to 24 months (d = 0.27). Even though the average iCAN-DO group participant surpassed a MCID in symptoms of anxiety (>2 p) at both long-term follow-ups, the differences did not reach statistical significance, either at 18 months (p = 0.10) or 24 months (p = 0.09). Positive effects of iCAN-DO compared with the SC were also shown for some secondary HRQoL-outcomes; social functioning at 18 months (p = 0.02) and 24 months (p = 0.001), and sleep problems at 24 months (p = 0.01).

CONCLUSION: A stepped-care internet-based intervention that has previously shown positive results for symptoms of depression at 10 months did show similar positive long-term effects also at 18 months. For symptoms of anxiety, no effect could be shown. The internet may provide an effective format for interventions to reduce symptoms of depression after cancer at patients' own choice of time, regardless of distance to a psycho-oncology clinic.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Anxiety, Cancer, Depression, Long-term follow-up, Psycho-educational intervention, Randomized controlled trial
National Category
Cancer and Oncology Psychiatry
Identifiers
urn:nbn:se:uu:diva-505889 (URN)10.1016/j.invent.2023.100625 (DOI)001055622800001 ()37273929 (PubMedID)
Funder
U‐Care: Better Psychosocial Care at Lower Cost? Evidence-based assessment and Psychosocial Care via Internet, a Swedish ExampleSwedish Research Council, 2009-1093Forte, Swedish Research Council for Health, Working Life and WelfareSwedish Cancer SocietyRegion UppsalaThe Breast Cancer Foundation
Available from: 2023-06-22 Created: 2023-06-22 Last updated: 2023-09-26Bibliographically approved
Ahmad, A., Premanandan, S., Langegård, U., Cajander, Å., Johansson, B., Carlsson, M. E. & Ehrsson, Y. T. (2023). Positive Design Framework for Carer-eSupport: A Qualitative Study to Support Informal Caregivers of Patients with Head and Neck Cancer in Sweden. JMIR Cancer, 9, Article ID e45748.
Open this publication in new window or tab >>Positive Design Framework for Carer-eSupport: A Qualitative Study to Support Informal Caregivers of Patients with Head and Neck Cancer in Sweden
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2023 (English)In: JMIR Cancer, E-ISSN 2369-1999, Vol. 9, article id e45748Article in journal (Refereed) Published
Abstract [en]

Background: Informal caregivers of patients with head and neck cancer (HNC), such as the patient’s spouse, other close relatives, or friends, can play an important role in home-based treatment and health care. Research shows that informal caregivers are usually unprepared for this responsibility and need support with taking care of patients and other daily life activities. These circumstances place them in a vulnerable position, and their well-being may be compromised. This study is part of our ongoing project Carer eSupport, which aims to develop a web-based intervention to facilitate informal caregivers in the home environment.

Objective: This study aimed to explore the situation and context of informal caregivers of patients with HNC and their needs for designing and developing a web-based intervention (Carer eSupport). In addition, we proposed a novel framework for the development of a web-based intervention aimed at promoting the well-being of informal caregivers. Methods: Focus groups were conducted with 15 informal caregivers and 13 healthcare professionals. Both informal caregivers and healthcare professionals were recruited from 3 university hospitals in Sweden. We adopted a thematic data analysis process to analyze the data.

Results: We investigated informal caregivers’ needs, critical factors for adoption, and desired functionalities of Carer eSupport.A total of 4 major themes, including information, web-based forum, virtual meeting place, and chatbot, emerged and were discussed by informal caregivers and health care professionals for Carer eSupport. However, most study participants did not like the idea of a chatbot for asking questions and retrieving information and expressed their concerns such as a lack of trust in robotic technologies and missing human contact while communicating with chatbots. The results from the focus groups were discussed through the lens of positive design research approaches.

Conclusions: This study provided an in-depth understanding of informal caregivers’ contexts and their preferred functions for a web-based intervention (Carer eSupport). Using the theoretical foundation of designing for well-being and positive design in the informal caregiving context, we proposed a positive design framework to support informal caregivers’ well-being. Our proposed framework might be helpful for human-computer interaction and user experience researchers to design meaningful health interventions with a clear focus on users’ well-being and positive emotions, especially for informal caregivers of patients with HNC.

Place, publisher, year, edition, pages
JMIR Publications, 2023
Keywords
eHealth, subjective well-being, positive design, adaptability, informal caregivers, head and neck cancer, preparedness to care
National Category
Human Computer Interaction
Research subject
Human-Computer Interaction; Health Care Research; Cancer Epidemiology
Identifiers
urn:nbn:se:uu:diva-505567 (URN)10.2196/45748 (DOI)001021663600001 ()37252765 (PubMedID)
Available from: 2023-06-20 Created: 2023-06-20 Last updated: 2024-01-11Bibliographically approved
Langegård, U., Cajander, Å., Ahmad, A., Carlsson, M. E., Nevo, E. O., Johansson, B. & Ehrsson, Y. T. (2023). Understanding the challenges and need for support of informal caregivers to individuals with head and neck cancer - A basis for developing internet-based support. European Journal of Oncology Nursing, 64, Article ID 102347.
Open this publication in new window or tab >>Understanding the challenges and need for support of informal caregivers to individuals with head and neck cancer - A basis for developing internet-based support
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2023 (English)In: European Journal of Oncology Nursing, ISSN 1462-3889, E-ISSN 1532-2122, Vol. 64, article id 102347Article in journal (Refereed) Published
Abstract [en]

Purpose

Being an informal caregiver of an individual with head and neck cancer can be demanding. Still, informal caregivers can provide valuable support to patients throughout the disease trajectory. The aim of this study was to explore informal caregivers’ views on their challenges and needs in attaining high preparedness for caregiving.

Methods

Fifteen informal caregivers of individuals with head- and neck cancer participated in a focus group discussion or an individual interview. Thematic analysis utilizing an inductive approach was performed.

Results

The results describe the challenges that informal caregivers to individuals with head and neck cancer perceive and their needs for support in preparedness for caregiving. Three main themes were found: Challenges of being an informal caregiver, Transformation in life and Informal caregiver’ needs of support and sharing care.

Conclusion

This study contributes to the understanding of the challenges for informal caregivers to individuals with head and neck cancer in increasing preparedness for caregiving. To improve preparedness for caregiving, informal caregivers need education, information and support regarding physical, psychological and social issues for individuals with head and neck cancer.

Place, publisher, year, edition, pages
Elsevier, 2023
National Category
Human Computer Interaction Nursing
Identifiers
urn:nbn:se:uu:diva-507017 (URN)10.1016/j.ejon.2023.102347 (DOI)001015131000001 ()
Available from: 2023-06-30 Created: 2023-06-30 Last updated: 2024-01-11Bibliographically approved
Söderström, L., Forslund, M., Johansson, B., Ottenblad, A. & Karlsson, A. (2022). Associations between dietary advice on modified fibre and lactose intakes and nutrient intakes in men with prostate cancer undergoing radiotherapy. Upsala Journal of Medical Sciences, 127(1), Article ID e8261.
Open this publication in new window or tab >>Associations between dietary advice on modified fibre and lactose intakes and nutrient intakes in men with prostate cancer undergoing radiotherapy
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2022 (English)In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 127, no 1, article id e8261Article in journal (Refereed) Published
Abstract [en]

Objectives: A variety of non-evidence-based dietary advice on modified fibre and lactose intakes are provided to patients undergoing pelvic radiotherapy to counteract treatment-related bowel symptoms. More knowledge on the nutritional consequences of such advice is needed. This study aimed to explore how advice on modified fibre and lactose intakes during pelvic radiotherapy was associated with nutrient intakes amongst patients with prostate cancer.

Methods: A total of 77 Swedish men who underwent radiotherapy (50/2 Gy + boost 20–30 Gy) in 2009–2014 due to prostate cancer were given dietary advice at radiotherapy onset (baseline) and at 4 and 8 weeks after radiotherapy onset, to modify their fibre and lactose intakes. At baseline, the participants completed a food frequency questionnaire (FFQ) and a 24-h dietary recall. At 4 and 8 weeks, the participants completed the FFQ and a 4-day estimated food record.

Fibre and lactose intakes were measured by intake scores calculated from the FFQs. Multiple linear regression models were used to analyse associations between intake scores and fibre- and lactose-related nutrients.

Results: In adjusted analyses, there were few significant associations between dietary advice on modified fibre and lactose intakes and observed intakes of fibre- and lactose-related nutrients. A more modified lactose intake was thus associated with a lower intake of calcium (P = 0.041), whilst a more modified fibre intake was associated with a higher value for the change in intake of vitamin C (P = 0.016).

Conclusions: Dietary advice on modified fibre and lactose intake was in most cases not significantly associated with altered nutrient intakes, rather the energy and nutrient intakes were mostly stable during the pelvic radiotherapy. More research is needed on the nutritional consequences of dietary advice on modified fibre and lactose intakes to reach consensus on if they should continue to be provided in the clinic.

Place, publisher, year, edition, pages
Upsala Medical Society, 2022
Keywords
Fibre, lactose, nutrient intake, prostate cancer, radiotherapy
National Category
Cancer and Oncology Nutrition and Dietetics
Identifiers
urn:nbn:se:uu:diva-479886 (URN)10.48101/ujms.v127.8261 (DOI)000813348500001 ()35756572 (PubMedID)
Funder
Swedish Cancer Society, CAN 2008/799
Available from: 2022-07-05 Created: 2022-07-05 Last updated: 2023-08-24Bibliographically approved
Ahmad, A., Cajander, Å., Johansson, B., Ehrsson, Y. T. & Langegård, U. (2022). Designing for Human Well-Being: A Case Study with Informal Caregivers of Individuals with Cancer. Studies in Health Technology and Informatics, 294, 214-218
Open this publication in new window or tab >>Designing for Human Well-Being: A Case Study with Informal Caregivers of Individuals with Cancer
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2022 (English)In: Studies in Health Technology and Informatics, ISSN 0926-9630, E-ISSN 1879-8365, Vol. 294, p. 214-218Article in journal (Refereed) Published
Abstract [en]

Informal Caregivers such as a spouse, other close relatives or friends of cancer patients can play an essential role in home-based treatment and care. However, the informal caregivers might not be prepared for this responsibility, and they might have several unmet requirements for taking care of patients in the home environment. The informal caregivers’ physical, social and psychological health is also profoundly affected due to the health conditions of their relatives. We propose a User-centred Positive Design as a hybrid framework by merging the traditional User-cantered design and positive design frameworks to enhance the informal caregivers’ subjective well-being. Our ongoing project (Carer-eSupport) will be used as a case study, and its main objective is to co-create and evaluate a web-based support system for informal caregivers of people with cancer. The proposed framework can be used for the design and development of health information systems with a special focus on users’ wellbeing and positive emotions.

Place, publisher, year, edition, pages
IOS Press, 2022
Keywords
Informal caregiving, Subjective well-being, Positive design, User- centered design, HCI, UCPD, Web-based support systems
National Category
Human Computer Interaction Medical and Health Sciences
Research subject
Computer Science with specialization in Human-Computer Interaction; Computer Science with specialization in Human-Computer Interaction
Identifiers
urn:nbn:se:uu:diva-475510 (URN)10.3233/shti220440 (DOI)
Available from: 2022-06-02 Created: 2022-06-02 Last updated: 2023-01-09Bibliographically approved
Hamberg Levedahl, K., Nilsson, A., Johansson, B. & Hedström, M. (2022). How persons with systemic mastocytosis describe the time between symptom onset and receiving diagnosis. Primary Health Care Research and Development, 23, Article ID e54.
Open this publication in new window or tab >>How persons with systemic mastocytosis describe the time between symptom onset and receiving diagnosis
2022 (English)In: Primary Health Care Research and Development, ISSN 1463-4236, E-ISSN 1477-1128, Vol. 23, article id e54Article in journal (Refereed) Published
Abstract [en]

Aim: The aim of the study was to explore how persons with systemic mastocytosis (SM) described the time between the onset of symptoms and signs and getting the diagnosis.

Background: SM is a rare disease caused by the accumulation of clonal mast cells with abnormal function. The symptoms and signs of the disease are varied, often diffuse and affect individuals differently. Due to this complexity, a multi-disciplinary diagnostic approach is required, in which general practitioners play an important part in identifying and referring patients relevant for such investigations.

Methods: Sixteen persons with SM were interviewed about their experiences of the time before the diagnosis was received. Systematic text condensation was used in the analysis process.

Findings: The time between symptom and signs onset and diagnosis was perceived as difficult. SM often had a complex and unpredictable effect on a person's daily life, long before diagnosis. In the analysis, three themes were found. Having symptoms and signs with an unknown cause included the participants' descriptions of numerous symptoms and signs, often years before diagnosis. These could be severe and result in worries for both participants and their next-of-kin. Dealing with the symptoms and signs encompassed the different ways in which the participants coped with the symptoms and signs, and sought relief. Being a patient without a diagnosis underlined the lack of information and knowledge within healthcare, often resulting in a delayed or incorrect diagnosis. The study highlighted the importance of a person-centred approach and the need to increase knowledge of the disease within primary care, to shorten this stressful and vulnerable time.

Place, publisher, year, edition, pages
Cambridges Institutes Press, 2022
Keywords
diagnosis delay, qualitative, rare disease, systemic mastocytosis, systematic text condensation
National Category
Nursing Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:uu:diva-484751 (URN)10.1017/S146342362200024X (DOI)000850449600001 ()36069067 (PubMedID)
Available from: 2022-09-16 Created: 2022-09-16 Last updated: 2022-09-16Bibliographically approved
Langegård, U., Cajander, Å., Carlsson, M. E., von Essen, L., Ahmad, A., Laurell, G., . . . Johansson, B. (2022). Internet-based support for informal caregivers to individuals with head and neck cancer (Carer eSupport): a study protocol for the development and feasibility testing of a complex online intervention. BMJ Open, 12(5), Article ID e057442.
Open this publication in new window or tab >>Internet-based support for informal caregivers to individuals with head and neck cancer (Carer eSupport): a study protocol for the development and feasibility testing of a complex online intervention
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2022 (English)In: BMJ Open, E-ISSN 2044-6055, Vol. 12, no 5, article id e057442Article in journal (Refereed) Published
Abstract [en]

It is strongly recommended that randomised controlled trials are preceded with an exploration of the needs of the target population and feasibility testing of the intervention. The present study protocol is set out to describe these steps in the development of a complex intervention.

The past decades’ transition of care from inpatient to outpatient settings has increased the complexity of caregivers’ responsibilities, which they may not be prepared for. There is a need to support informal caregivers (ICs) to prepare them for caregiving and decrease the caregiver burden. The main aim of this study is to describe the development of an internet-based intervention (Carer eSupport) to improve ICs’ ability to support individuals with head and neck cancer and to describe the testing of the feasibility and acceptability of Carer eSupport.

Methods and analysis

This is a multicentre study involving the ear, nose and throat clinics and the oncology and radiotherapy clinics at three university hospitals. The study protocol comprises two phases, development and feasibility testing, using the Medical Research Council framework for developing a complex intervention. Carer eSupport will be based on the results from focus group discussions with ICs and healthcare professionals (planned for n=6–8 in respective groups) and scientific evidence, the Social Cognitive Theory and the Theory of Acceptance and Use of Technology. The feasibility testing will include 30 ICs who will have access to Carer eSupport for 1 month. The feasibility testing will be evaluated with a mixed-method design.

Ethics and dissemination

All procedures have been approved by the Ethics Committee at Uppsala University (Dnr: 2020-04650). Informed consent will be obtained before enrolment of patients, their ICs and healthcare staff. The feasibility testing is registered at Clinicaltrials.gov (Identifier: NCT05028452). Findings will be disseminated in peer-reviewed journal publications.

Place, publisher, year, edition, pages
BMJ Publishing Group LtdBMJ, 2022
National Category
Cancer and Oncology Psychology
Research subject
Psychology; Oncology
Identifiers
urn:nbn:se:uu:diva-477094 (URN)10.1136/bmjopen-2021-057442 (DOI)000803051800005 ()35623759 (PubMedID)
Available from: 2022-06-14 Created: 2022-06-14 Last updated: 2024-01-15Bibliographically approved
Ax, A.-K., Husberg, M., Johansson, B., Demmelmaier, I., Berntsen, S., Sjövall, K., . . . Davidson, T. (2022). Long-term resource utilisation and associated costs of exercise during (neo)adjuvant oncological treatment: the Phys-Can project. Acta Oncologica, 61(7), 888-896
Open this publication in new window or tab >>Long-term resource utilisation and associated costs of exercise during (neo)adjuvant oncological treatment: the Phys-Can project
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2022 (English)In: Acta Oncologica, ISSN 0284-186X, E-ISSN 1651-226X, Vol. 61, no 7, p. 888-896Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Exercise during oncological treatment is beneficial to patient health and can counteract the side effects of treatment. Knowledge of the societal costs associated with an exercise intervention, however, is limited. The aims of the present study were to evaluate the long-term resource utilisation and societal costs of an exercise intervention conducted during (neo)adjuvant oncological treatment in a randomised control trial (RCT) versus usual care (UC), and to compare high-intensity (HI) versus low-to-moderate intensity (LMI) exercise in the RCT.

METHODS: We used data from the Physical Training and Cancer (Phys-Can) project. In the RCT, 577 participants were randomised to HI or to LMI of combined endurance and resistance training for 6 months, during oncological treatment. The project also included 89 participants with UC in a longitudinal observational study. We measured at baseline and after 18 months. Resource utilisation and costs of the exercise intervention, health care, and productivity loss were compared using analyses of covariance (RCT vs. UC) and t test (HI vs. LMI).

RESULTS: Complete data were available for 619 participants (RCT HI: n = 269, LMI: n = 265, and UC: n = 85). We found no difference in total societal costs between the exercise intervention groups in the RCT and UC. However, participants in the RCT had lower rates of disability pension days (p < .001), corresponding costs (p = .001), and pharmacy costs (p = .018) than the UC group. Nor did we find differences in resource utilisation or costs between HI and LMI exercise int the RCT.

CONCLUSION: Our study showed no difference in total societal costs between the comprehensive exercise intervention and UC or between the exercise intensities. This suggests that exercise, with its well-documented health benefits during oncological treatment, produces neither additional costs nor savings.

Place, publisher, year, edition, pages
Taylor & Francis, 2022
Keywords
Cancer, cost analysis, costs, exercise, health care costs, sick leave
National Category
Physiotherapy Cancer and Oncology
Identifiers
urn:nbn:se:uu:diva-477208 (URN)10.1080/0284186X.2022.2075238 (DOI)000799825800001 ()35607981 (PubMedID)
Available from: 2022-06-15 Created: 2022-06-15 Last updated: 2024-03-18Bibliographically approved
Projects
Care: U-CARE: Internet based screening and stepped care for cancer patients with anxiety or depression symptoms – a randomized controlled multicenter study [2014-04960_Forte]; Uppsala UniversityInternet based support (Carer eSupport) for informal caregivers of patients with head and neck cancer – a multicentre randomized controlled trial [2019-01231_VR]; Uppsala University
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0001-6226-6849

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