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Bardel, Annika
Publications (10 of 18) Show all publications
Bardel, A., Wallander, M.-A., Wallman, T., Rosengren, A., Johansson, S., Eriksson, H. & Svärdsudd, K. (2019). Age and sex related self-reported symptoms in a general population across 30 years: Patterns of reporting and secular trend. PLoS ONE, 14(2), Article ID e0211532.
Open this publication in new window or tab >>Age and sex related self-reported symptoms in a general population across 30 years: Patterns of reporting and secular trend
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2019 (English)In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 14, no 2, article id e0211532Article in journal (Refereed) Published
Abstract [en]

Objective To study age and sex specific prevalence of 30 symptoms in random samples from the general population and to analyze possible secular trends across time. Study population The study was based on data from eight on-going Swedish cohort studies, with baseline investigations performed between 1973 and 2003. Samples were drawn from the general population of the cities of Gothenburg and Eskilstuna, and of Uppsala County. Overall, 20,160 subjects were sampled, 14,470 (71.8%) responded, of whom 12.000 were unique subjects, and 2548 were part of more than one sample. Methods The Complaint score sub-scale of the Gothenburg Quality of Life instrument, listing 30 general symptoms was used. Responders were asked to indicate which symptoms they had experienced during the last three months. Results Women reported on average 7.8 symptoms, and men 5.3 (p<0.0001). Women reported higher prevalence than men for 24 of the 30 symptoms. In multivariate analyses four patterns of prevalence across age were identified in both men and women; increasing prevalence, decreasing, stable and biphasic prevalence. The symptoms in the various pattern groups differed somewhat between men and women. However, symptoms related to strain were prominent among symptoms decreasing with age. Moreover, there were secular trends. Across all symptoms reporting prevalence increased over time in men (p<0.001) as well as in women (p<0.0001). Conclusions Women reported higher total symptom prevalence than men. Symptoms related to health generally increased with age, while symptoms related to stress decreased markedly. Significant secular trends across time regarding symptom prevalence were found.

Place, publisher, year, edition, pages
PUBLIC LIBRARY SCIENCE, 2019
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:uu:diva-377595 (URN)10.1371/journal.pone.0211532 (DOI)000457744200030 ()30716129 (PubMedID)
Funder
Forte, Swedish Research Council for Health, Working Life and Welfare
Available from: 2019-03-01 Created: 2019-03-01 Last updated: 2019-03-07Bibliographically approved
Hovelius, B. (., Andersson, C., Bardel, A., Björkelund, C., Borgquist, L., Engfeldt, P., . . . Nilsson, G. (Eds.). (2015). Allmänmedicin: Huvudredaktör Steinar Hunskår. Studentlitteratur AB
Open this publication in new window or tab >>Allmänmedicin: Huvudredaktör Steinar Hunskår
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2015 (Swedish)Conference proceedings (editor) (Other academic)
Place, publisher, year, edition, pages
Studentlitteratur AB, 2015. p. 1102
National Category
General Practice
Identifiers
urn:nbn:se:uu:diva-268549 (URN)978-91-44-08446-6 (ISBN)
Available from: 2015-12-07 Created: 2015-12-07 Last updated: 2018-01-10
Bardel, A., Wallander, M.-A. & Svärdsudd, K. (2015). Factors associated with adherence to drug therapy. In: Mehmet Ungen & Carl Steylaerts (Ed.), The world book of family medicine: European edition published on the ocction of the 20th Anniversary of WONCA Europe, Istanbul, October 2015 (pp. 100-102). Ljubljana: Narodna in univerzitetna
Open this publication in new window or tab >>Factors associated with adherence to drug therapy
2015 (English)In: The world book of family medicine: European edition published on the ocction of the 20th Anniversary of WONCA Europe, Istanbul, October 2015 / [ed] Mehmet Ungen & Carl Steylaerts, Ljubljana: Narodna in univerzitetna , 2015, p. 100-102Chapter in book (Other academic)
Place, publisher, year, edition, pages
Ljubljana: Narodna in univerzitetna, 2015
National Category
General Practice
Identifiers
urn:nbn:se:uu:diva-280548 (URN)978-961-281-983-5 (ISBN)
Available from: 2016-03-11 Created: 2016-03-11 Last updated: 2018-01-10Bibliographically approved
Björk, A., Andersson, Å., Johansson, G., Björkegren, K., Bardel, A. & Kristiansson, P. (2013). Evaluation of sun holiday, diet habits, origin and other factors as determinants of vitamin D status in Swedish primary health care patients: a cross-sectional study with regression analysis of ethnic Swedish and immigrant women. BMC Family Practice, 14, 129
Open this publication in new window or tab >>Evaluation of sun holiday, diet habits, origin and other factors as determinants of vitamin D status in Swedish primary health care patients: a cross-sectional study with regression analysis of ethnic Swedish and immigrant women
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2013 (English)In: BMC Family Practice, ISSN 1471-2296, E-ISSN 1471-2296, Vol. 14, p. 129-Article in journal (Refereed) Published
Abstract [en]

Background

Determinants of vitamin D status measured as 25-OH-vitamin D in blood are exposure to sunlight and intake of vitamin D through food and supplements. It is unclear how large the contributions are from these determinants in Swedish primary care patients, considering the low radiation of UVB in Sweden and the fortification of some foods. Asian and African immigrants in Norway and Denmark have been found to have very low levels, but it is not clear whether the same applies to Swedish patients. The purpose of our study was to identify contributors to vitamin D status in Swedish women attending a primary health care centre at latitude 60°N in Sweden.

Methods

In this cross-sectional, observational study, 61 female patients were consecutively recruited between January and March 2009, irrespective of reason for attending the clinic. The women were interviewed about their sun habits, smoking, education and food intake at a personal appointment and blood samples were drawn for measurements of vitamin D and calcium concentrations.

Results

Plasma concentration of 25-OH-vitamin D below 25 nmol/L was found in 61% (19/31) of immigrant and 7% (2/30) of native women. Multivariate analysis showed that reported sun holiday of one week during the last year at latitude below 40°N with the purpose of sun-bathing and native origin, were significantly, independently and positively associated with 25-OH-vitamin D concentrations in plasma with the strongest association for sun holiday during the past year.

Conclusions

Vitamin D deficiency was common among the women in the present study, with sun holiday and origin as main determinants of 25-OH-vitamin D concentrations in plasma. Given a negative effect on health this would imply needs for vitamin D treatment particularly in women with immigrant background who have moved from lower to higher latitudes.

Keywords: Vitamin D; Sun habits; Immigrant; Women; Primary health care

National Category
General Practice
Identifiers
urn:nbn:se:uu:diva-208596 (URN)10.1186/1471-2296-14-129 (DOI)000324297400001 ()
Available from: 2013-10-04 Created: 2013-10-04 Last updated: 2018-01-19Bibliographically approved
Halford, C., Welin, C., Bogefeldt, J., Wallman, T., Rosengren, A., Bardel, A., . . . Svärdsudd, K. (2012). A population-based study of nearly 15 000 observations among Swedish women and men during 1973-2003. BMJ Open, 2(6), e001353
Open this publication in new window or tab >>A population-based study of nearly 15 000 observations among Swedish women and men during 1973-2003
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2012 (English)In: BMJ Open, ISSN 2044-6055, E-ISSN 2044-6055, Vol. 2, no 6, p. e001353-Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES:

Global self-rated health (SRH) has become extensively used as an outcome measure in population health surveillance. The aim of this study was to analyse the effects of age and secular trend (year of investigation) on SRH.

DESIGN:

Prospective cohort study, using population-based data from eight ongoing cohort studies, with sampling performed between 1973 and 2003.

SETTING:

Sweden.

PARTICIPANTS:

11 880 women and men, aged 25-99 years, providing 14 470 observations.

PRIMARY OUTCOME MEASURE:

Global SRH.

RESULTS:

In multiple ordinal logistic regression analyses, adjusted for the effects of covariates, there were independent effects of age (p<0.0001) and of year of investigation (p<0.0001) on SRH. In women the association was linear, showing lower levels of SRH with increased age, and more recent year of investigation. In men the association was curvilinear, and thus more complex. The final model explained 76.2% of the SRH variance in women and 74.5% of the variance in men.

CONCLUSIONS:

SRH was strongly and inversely associated with age in both sexes, after adjustment for other outcome-affecting variables. There was a strongly significant effect of year of investigation indicating a change in SRH, in women towards lower levels over calendar time, in men with fluctuations across time.

National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:uu:diva-189474 (URN)10.1136/bmjopen-2012-001353 (DOI)000315081400025 ()23117561 (PubMedID)
Available from: 2013-01-02 Created: 2013-01-02 Last updated: 2017-12-06Bibliographically approved
Halford, C., Wallman, T., Welin, L., Rosengren, A., Bardel, A., Johansson, S., . . . Svärdsudd, K. (2012). Effects of self-rated health on sick leave, disability pension, hospital admissions and mortality: A population-based longitudinal study of nearly 15,000 observations among Swedish women and men. BMC Public Health, 12(1), 1103
Open this publication in new window or tab >>Effects of self-rated health on sick leave, disability pension, hospital admissions and mortality: A population-based longitudinal study of nearly 15,000 observations among Swedish women and men
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2012 (English)In: BMC Public Health, ISSN 1471-2458, E-ISSN 1471-2458, Vol. 12, no 1, p. 1103-Article in journal (Refereed) Published
Abstract [en]

BACKGROUND:

Simple global self-ratings of health (SRH) have become increasingly used in national and international public health monitoring, and in recent decades recommended as a standard part of health surveys. Monitoring developments in population health requires identification and use of health measures, valid in relation to targets for population health. The aim of the present study was to investigate associations between SRH and sick leave, disability pension, hospital admissions, and mortality, adjusted for effects of significant covariates, in a large population-based cohort.

METHODS:

The analyses were based on screening data from eight population-based cohorts in southern and central Sweden, and on official register data regarding sick-leave, disability pension, hospital admissions, and death, with little or no data loss. Sampling was performed 1973--2003. The study population consisted of 11,880 women and men, age 25--99 years, providing 14,470 observations. Information on SRH, socio-demographic data, lifestyle variables and somatic and psychological symptoms were obtained from questionnaires.

RESULTS:

There was a significant negative association between SRH and sick leave (Beta -13.2, p<0.0001, and -9.5, p<0.01, in women and men, respectively), disability pension (Hazard ratio 0.77, p<0.0001 and 0.76, p<0.0001, in women and men, respectively), and mortality, adjusted for covariates. SRH was also significantly associated with hospital admissions in men (Hazard ratio 0.87, p<0.0001), but not in women (Hazard ratio 0.96, p0.20). Associations between SRH on the one hand, and sick leave, disability pension, hospital admission, and mortality, on the other, were robust during the follow-up period.

CONCLUSIONS:

SRH had strong predictive validity in relation to use of social insurance facilities and health care services, and to mortality. Associations were strong and robust during follow-up.

National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:uu:diva-189468 (URN)10.1186/1471-2458-12-1103 (DOI)000317749500001 ()23259777 (PubMedID)
Available from: 2013-01-02 Created: 2013-01-02 Last updated: 2017-12-06Bibliographically approved
Halford, C., Welin, C., Bogefeldt, J. P., Wallman, T., Rosengren, A., Bardel, A., . . . Svärdsudd, K. F. (2010). Effects of age and secular trends on self-rated health: a population-based study of nearly 15,000 observations among Swedish women and men during 1973-2003.
Open this publication in new window or tab >>Effects of age and secular trends on self-rated health: a population-based study of nearly 15,000 observations among Swedish women and men during 1973-2003
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2010 (English)Article in journal (Other academic) Submitted
Identifiers
urn:nbn:se:uu:diva-132360 (URN)
Available from: 2010-10-26 Created: 2010-10-19 Last updated: 2012-10-30Bibliographically approved
Bardel, A., Wallander, M.-A., Wedel, H. & Svärdsudd, K. (2009). Age-specific symptom prevalence in women 35-64 years old: A population-based study. BMC Public Health, 9, 37
Open this publication in new window or tab >>Age-specific symptom prevalence in women 35-64 years old: A population-based study
2009 (English)In: BMC Public Health, ISSN 1471-2458, E-ISSN 1471-2458, Vol. 9, p. 37-Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Symptom prevalence is generally believed to increase with age. The aim of this study was to evaluate the age specific prevalence of 30 general symptoms among Swedish middle-aged women. METHODS: A cross-sectional postal questionnaire study in seven Swedish counties in a random sample of 4,200 women 35-64 years old, with 2,991 responders. Thirty general symptoms included in the Complaint Score subscale of the Gothenburg Quality of Life Instrument were used. RESULTS: Four groups of age specific prevalence patterns were identified after adjustment for the influence of educational level, perceived health and mood, body mass index, smoking habits, use of hormone replacement therapy, and use of other symptom relieving therapy. Only five symptoms (insomnia, leg pain, joint pain, eye problems and impaired hearing) increased significantly with age. Eleven symptoms (general fatigue, headache, irritability, melancholy, backache, exhaustion, feels cold, cries easily, abdominal pain, dizziness, and nausea) decreased significantly with age. Two symptoms (sweating and impaired concentration) had a biphasic course with a significant increase followed by a significant decrease. The remaining twelve symptoms (difficulty in relaxing, restlessness, overweight, coughing, breathlessness, diarrhoea, chest pain, constipation, nervousness, poor appetite, weight loss, and difficulty in urinating) had stable prevalence with age. CONCLUSION: Symptoms did not necessarily increase with age instead symptoms related to stress-tension-depression decreased.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-96257 (URN)10.1186/1471-2458-9-37 (DOI)000264288600001 ()19171031 (PubMedID)
Available from: 2007-10-03 Created: 2007-10-03 Last updated: 2017-12-14Bibliographically approved
Hovelius, B. (., Andersson, C., Bardel, A., Björkelund, C., Borgquist, L. & Furhoff, A.-K. (Eds.). (2007). Allmänmedicin: Huvudredaktör Steinar Hunskår. Studentlitteratur AB
Open this publication in new window or tab >>Allmänmedicin: Huvudredaktör Steinar Hunskår
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2007 (Swedish)Conference proceedings (editor) (Other academic)
Place, publisher, year, edition, pages
Studentlitteratur AB, 2007. p. 883
National Category
General Practice
Identifiers
urn:nbn:se:uu:diva-268550 (URN)978-91-44-02798-2 (ISBN)
Available from: 2015-12-07 Created: 2015-12-07 Last updated: 2018-01-10
Bardel, A., Wallander, M.-A. & Svärdsudd, K. (2007). Factors associated with adherence to drug therapy: a population-based study. European Journal of Clinical Pharmacology, 63(3), 307-314
Open this publication in new window or tab >>Factors associated with adherence to drug therapy: a population-based study
2007 (English)In: European Journal of Clinical Pharmacology, ISSN 0031-6970, E-ISSN 1432-1041, Vol. 63, no 3, p. 307-314Article in journal (Refereed) Published
Abstract [en]

Objective  To investigate adherence to prescription in a female population aged 35–65 years.

Design  Postal questionnaire study of 2991 randomly sampled 35- to 64-year-old women in seven provinces of central Sweden. Methods  The study was performed in 1995 as a cross-sectional postal questionnaire study in seven counties in central Sweden. The questionnaire was sent to a random sample of 4200 women between the ages of 35 and 64, of whom 2991 (71.2%) responded. The questionnaire asked about drugs prescribed during the past year and about factors potentially affecting adherence. Results  The same women had different degrees of adherence to different medications. A large number of factors were associated with adherence. Multivariate analysis revealed that age, scheduled check-up, perceived importance of medication, concerns about medication safety and taking medication for a respiratory or a cardiovascular disease were significantly related to adherence. Adherence ranged from 15–98% depending on these factors, and was the lowest among young women who regarded their medication as unimportant and who had no scheduled check-up; the highest reported adherence was found among elderly women who regarded their medication as important and who had a scheduled check-up. Conclusion  Factors that were associated with the perceived importance of medication had a positive effect on adherence, while concerns about medication safety had a negative effect.

Keywords
Adherence, Communication skills, Epidemiology, Prescription, Women
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-96255 (URN)10.1007/s00228-006-0246-4 (DOI)000244091900012 ()17211620 (PubMedID)
Available from: 2007-10-03 Created: 2007-10-03 Last updated: 2017-12-14Bibliographically approved
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