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Hellström-Westas, LenaORCID iD iconorcid.org/0000-0003-3498-6069
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Publications (10 of 98) Show all publications
Vaz, T. F., Canto Moreira, N., Hellström-Westas, L., Naseh, N., Matela, N. & Ferreira, H. A. (2024). Brain Extraction Methods in Neonatal Brain MRI and Their Effects on Intracranial Volumes. Applied Sciences, 14(4), Article ID 1339.
Open this publication in new window or tab >>Brain Extraction Methods in Neonatal Brain MRI and Their Effects on Intracranial Volumes
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2024 (English)In: Applied Sciences, E-ISSN 2076-3417, Vol. 14, no 4, article id 1339Article in journal (Refereed) Published
Abstract [en]

Magnetic resonance imaging (MRI) plays an important role in assessing early brain development and injury in neonates. When using an automated volumetric analysis, brain tissue segmentation is necessary, preceded by brain extraction (BE) to remove non-brain tissue. BE remains challenging in neonatal brain MRI, and despite the existence of several methods, manual segmentation is still considered the gold standard. Therefore, the purpose of this study was to assess different BE methods in the MRI of preterm neonates and their effects on the estimation of intracranial volumes (ICVs). This study included twenty-two premature neonates (mean gestational age ± standard deviation: 28.4 ± 2.1 weeks) with MRI brain scans acquired at term, without detectable lesions or congenital conditions. Manual segmentation was performed for T2-weighted scans to establish reference brain masks. Four automated BE methods were used: Brain Extraction Tool (BET2); Simple Watershed Scalping (SWS); HD Brain Extraction Tool (HD-BET); and SynthStrip. Regarding segmentation metrics, HD-BET outperformed the other methods with median improvements of +0.031 (BET2), +0.002 (SWS), and +0.011 (SynthStrip) points for the dice coefficient; and −0.786 (BET2), −0.055 (SWS), and −0.124 (SynthStrip) mm for the mean surface distance. Regarding ICVs, SWS and HD-BET provided acceptable levels of agreement with manual segmentation, with mean differences of −1.42% and 2.59%, respectively.

Place, publisher, year, edition, pages
MDPI, 2024
Keywords
brain extraction, intracranial volume, neonatal MRI, segmentation, skull stripping
National Category
Radiology, Nuclear Medicine and Medical Imaging Medical Image Processing
Identifiers
urn:nbn:se:uu:diva-525441 (URN)10.3390/app14041339 (DOI)001170606900001 ()
Available from: 2024-03-22 Created: 2024-03-22 Last updated: 2024-03-22Bibliographically approved
Karimi, A., Setänen, S., Larsson, E., Holmström, G., Fredriksson Kaul, Y., Kochukhova, O., . . . Wikström, J. (2024). Brain MRI findings and their association with visual impairment in young adolescents born very preterm. Neuroradiology, 66(1), 145-154
Open this publication in new window or tab >>Brain MRI findings and their association with visual impairment in young adolescents born very preterm
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2024 (English)In: Neuroradiology, ISSN 0028-3940, E-ISSN 1432-1920, Vol. 66, no 1, p. 145-154Article in journal (Refereed) Published
Abstract [en]

Purpose

Very preterm birth increases risk for neonatal white matter injury, but there is limited data on to what extent this persists into adolescence and how this relates to ophthalmological outcomes. The aim of this study was to assess brain MRI findings in 12-year-old children born very preterm compared to controls and their association with concurrent ophthalmological outcomes.

Methods

We included 47 children born very preterm and 22 full-term controls (gestational age <32 and >37 weeks, respectively). Brain MRI findings were studied in association with concurrent ophthalmological outcomes at 12-year follow-up.

Results

Evans index (0.27 vs 0.25, p<0.001) and a proposed “posterior ventricle index” (0.47 vs 0.45, p=0.018) were increased in children born very preterm. Higher gestational age associated with larger corpus callosum area (β=10.7, 95%CI 0.59–20.8). Focal white matter lesions were observed in 15 (32%) of very preterm children and in 1 (5%) of full-term controls. Increased posterior ventricle index increased risk for visual acuity ≤1.0 (OR=1.07×1011, 95%CI=7.78–1.48×1021) and contrast sensitivity <0.5 (OR=2.6×1027, 95%CI=1.9×108–3.5×1046). Decreased peritrigonal white matter thickness associated with impaired visual acuity (β=0.04, 95%CI 0.002–0.07).

Conclusion

More white matter lesions and evidence of lower white matter volume were found in children born very preterm compared with full-term controls at 12-year follow-up. The association between larger posterior ventricle index and reduced visual acuity and contrast sensitivity suggests disturbances of the posterior visual pathway due to diffuse white matter lesions.

Place, publisher, year, edition, pages
Springer, 2024
Keywords
Long-term follow-up, Visual impairment, White matter injury, Gestational age, Preterm birth
National Category
Radiology, Nuclear Medicine and Medical Imaging Pediatrics Ophthalmology
Identifiers
urn:nbn:se:uu:diva-515632 (URN)10.1007/s00234-023-03235-5 (DOI)001089850100002 ()37870588 (PubMedID)
Funder
Swedish Research Council, 2016/03109Uppsala University
Available from: 2023-11-08 Created: 2023-11-08 Last updated: 2024-02-21Bibliographically approved
Vayssiere, C., Yli, B., Ayres-de-Campos, D., Ugwumadu, A., Loussert, L., Hellström-Westas, L., . . . Roth, G.-E. (2024). EUROPEAN ASSOCIATION OF PERINATAL MEDICINE (EAPM) Position statement: Use of appropriate terminology for situations related to inadequate fetal oxygenation in labor. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 294, 55-57
Open this publication in new window or tab >>EUROPEAN ASSOCIATION OF PERINATAL MEDICINE (EAPM) Position statement: Use of appropriate terminology for situations related to inadequate fetal oxygenation in labor
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2024 (English)In: European Journal of Obstetrics, Gynecology, and Reproductive Biology, ISSN 0301-2115, E-ISSN 1872-7654, Vol. 294, p. 55-57Article in journal (Refereed) Published
Abstract [en]

In high-resource countries, adverse perinatal outcomes are currently rare in term, non-malformed fetuses, undergoing labor, but they remain a leading cause of medico-legal dispute. Precise terminology is important to describe situations related to inadequate fetal oxygenation in labor, to ensure appropriate communication between healthcare professionals and adequate transmission of information to parents. This position statement provides consensus definitions from European perinatologists and midwives regarding the most appropriate terminology to describe situations related to inadequate fetal oxygenation in labor: suspected fetal hypoxia, severe newborn acidemia, newborn metabolic acidosis, and hypoxic-ischemic encephalopathy. It also identifies terms that are imprecise or nonspecific to this situation, and should therefore be avoided by healthcare professionals: fetal well-being, fetal stress, fetal distress, non-reassuring fetal state, and birth asphyxia.

Place, publisher, year, edition, pages
Elsevier, 2024
Keywords
Intrapartum care, Fetal hypoxia, Severe fetal acidemia, Fetal metabolic acidosis, Hypoxic-ischemic encephalopathy
National Category
Obstetrics, Gynecology and Reproductive Medicine Pediatrics
Identifiers
urn:nbn:se:uu:diva-531615 (URN)10.1016/j.ejogrb.2024.01.006 (DOI)001161033300001 ()38218158 (PubMedID)
Available from: 2024-06-17 Created: 2024-06-17 Last updated: 2024-06-17Bibliographically approved
Challis, P., Kallen, K., Bjorklund, L., Elfvin, A., Farooqi, A., Hakansson, S., . . . Domellof, M. (2024). Factors associated with the increased incidence of necrotising enterocolitis in extremely preterm infants in Sweden between two population-based national cohorts (2004-2007 vs 2014-2016). Archives of Disease in Childhood: Fetal and Neonatal Edition, 109(1), 87-93
Open this publication in new window or tab >>Factors associated with the increased incidence of necrotising enterocolitis in extremely preterm infants in Sweden between two population-based national cohorts (2004-2007 vs 2014-2016)
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2024 (English)In: Archives of Disease in Childhood: Fetal and Neonatal Edition, ISSN 1359-2998, E-ISSN 1468-2052, Vol. 109, no 1, p. 87-93Article in journal (Refereed) Published
Abstract [en]

Objective To investigate potential risk factors behind the increased incidence of necrotising enterocolitis (NEC) in Swedish extremely preterm infants.Design Registry data from two population-based national cohorts were studied. NEC diagnoses (Bell stage >= II) were validated against hospital records.Patients All liveborn infants <27 weeks of gestation 2004-2007 (n=704) and 2014-2016 (n=895) in Sweden.Main outcome measures NEC incidence.Results The validation process resulted in a 28% reduction of NEC cases but still confirmed a higher NEC incidence in the later epoch compared with the earlier (73/895 (8.2%) vs 27/704 (3.8%), p=0.001), while the composite of NEC or death was lower (244/895 (27.3%) vs 229/704 (32.5%), p=0.022). In a multivariable Cox regression model, censored for mortality, there was no significant difference in early NEC (0-7 days of life) between epochs (HR=0.9 (95% CI 0.5 to 1.9), p=0.9), but being born in the later epoch remained an independent risk factor for late NEC (>7 days) (HR=2.7 (95% CI 1.5 to 5.0), p=0.001). In propensity score analysis, a significant epoch difference in NEC incidence (12% vs 2.8%, p<0.001) was observed only in the tertile of infants at highest risk of NEC, where the 28-day mortality was lower in the later epoch (35% vs 50%, p=0.001). More NEC cases were diagnosed with intramural gas in the later epoch (33/73 (45.2%) vs 6/26 (23.1%), p=0.047).Conclusions The increase in NEC incidence between epochs was limited to cases occurring after 7 days of life and was partly explained by increased survival in the most extremely preterm infants. Misclassification of NEC is common.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2024
Keywords
Neonatology, Gastroenterology
National Category
Cardiac and Cardiovascular Systems Gastroenterology and Hepatology Pediatrics
Identifiers
urn:nbn:se:uu:diva-531652 (URN)10.1136/archdischild-2023-325784 (DOI)001080788400001 ()37788898 (PubMedID)
Funder
Region Stockholm, 2020-0443Swedish Research Council, 2019-01005Swedish Research Council, 2020-01236Swedish Heart Lung Foundation, 20200808Swedish Research CouncilEU, Horizon 2020
Available from: 2024-06-17 Created: 2024-06-17 Last updated: 2024-06-17Bibliographically approved
Farooqi, A., Hakansson, S., Serenius, F., Kallen, K., Bjorklund, L., Normann, E., . . . Norman, M. (2024). One-year survival and outcomes of infants born at 22 and 23 weeks of gestation in Sweden 2004-2007, 2014-2016 and 2017-2019. Archives of Disease in Childhood: Fetal and Neonatal Edition, 109(1), 10-17
Open this publication in new window or tab >>One-year survival and outcomes of infants born at 22 and 23 weeks of gestation in Sweden 2004-2007, 2014-2016 and 2017-2019
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2024 (English)In: Archives of Disease in Childhood: Fetal and Neonatal Edition, ISSN 1359-2998, E-ISSN 1468-2052, Vol. 109, no 1, p. 10-17Article in journal (Refereed) Published
Abstract [en]

Objective: To explore associations between perinatal activity and survival in infants born at 22 and 23 weeks of gestation in Sweden.

Design/Setting: Data on all births at 22 and 23 weeks' gestational age (GA) were prospectively collected in 2004-2007 (T1) or obtained from national registers in 2014-2016 (T2) and 2017-2019 (T3). Infants were assigned perinatal activity scores based on 3 key obstetric and 4 neonatal interventions.

Main outcome: One-year survival and survival without major neonatal morbidities (MNM): intraventricular haemorrhage grade 3-4, cystic periventricular leucomalacia, surgical necrotising enterocolitis, retinopathy of prematurity stage 3-5 or severe bronchopulmonary dysplasia. The association of GA-specific perinatal activity score and 1-year survival was also determined.

Results: 977 infants (567 live births and 410 stillbirths) were included: 323 born in T1, 347 in T2 and 307 in T3. Among live-born infants, survival at 22 weeks was 5/49 (10%) in T1 and rose significantly to 29/74 (39%) in T2 and 31/80 (39%) in T3. Survival was not significantly different between epochs at 23 weeks (53%, 61% and 67%). Among survivors, the proportions without MNM in T1, T2 and T3 were 20%, 17% and 19% for 22 weeks and 17%, 25% and 25% for 23 weeks' infants (p>0.05 for all comparisons). Each 5-point increment in GA-specific perinatal activity score increased the odds for survival in first 12 hours of life (adjusted OR (aOR) 1.4; 95% CI 1.3 to 1.6) in addition to 1-year survival (aOR 1.2; 95% CI 1.1 to 1.3), and among live-born infants it was associated with increased survival without MNM (aOR 1.3; 95% CI 1.1 to 1.4).

Conclusion: Increased perinatal activity was associated with reduced mortality and increased chances of survival without MNM in infants born at 22 and 23 weeks of GA.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2024
Keywords
neonatology, paediatrics
National Category
Pediatrics Public Health, Global Health, Social Medicine and Epidemiology Obstetrics, Gynecology and Reproductive Medicine
Identifiers
urn:nbn:se:uu:diva-533247 (URN)10.1136/archdischild-2022-325164 (DOI)001006756400001 ()37290903 (PubMedID)
Available from: 2024-07-01 Created: 2024-07-01 Last updated: 2024-07-01Bibliographically approved
Tran, H. T., Le, H. T., Tran, D. M., Nguyen, G. T., Hellström-Westas, L., Alfven, T. & Olson, L. (2024). Therapeutic hypothermia after perinatal asphyxia in Vietnam: medium-term outcomes at 18 months - a prospective cohort study. BMJ Paediatrics Open, 8(1), Article ID e002208.
Open this publication in new window or tab >>Therapeutic hypothermia after perinatal asphyxia in Vietnam: medium-term outcomes at 18 months - a prospective cohort study
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2024 (English)In: BMJ Paediatrics Open, E-ISSN 2399-9772, Vol. 8, no 1, article id e002208Article in journal (Refereed) Published
Abstract [en]

Aim To determine neurodevelopmental outcome at 18 months after therapeutic hypothermia for hypoxic-ischaemic encephalopathy (HIE) infants in Vietnam, a low-middle-income country. Method Prospective cohort study investigating outcomes at 18 months in severely asphyxiated outborn infants who underwent therapeutic hypothermia for HIE in Hanoi, Vietnam, during the time period 2016-2019. Survivors were examined at discharge and at 6 and 18 months by a neonatologist, a neurologist and a rehabilitation physician, who were blinded to the infants' clinical severity during hospitalisation using two assessment tools: the Ages and Stages Questionnaire (ASQ) and the Hammersmith Infant Neurological Examination (HINE), to detect impairments and promote early interventions for those who require it. Results In total, 130 neonates, 85 (65%) with moderate and 45 (35%) with severe HIE, underwent therapeutic hypothermia treatment using phase change material. Forty-three infants (33%) died during hospitalisation and in infancy. Among the 87 survivors, 69 (79%) completed follow-up until 18 months. Nineteen children developed cerebral palsy (8 diplegia, 3 hemiplegia, 8 dyskinetic), and 11 had delayed neurodevelopment. At each time point, infants with a normal or delayed neurodevelopment had significantly higher ASQ and HINE scores (p<0.05) than those with cerebral palsy. Conclusion The rates of mortality and adverse neurodevelopment rate were high and comparable to recently published data from other low-middle-income settings. The ASQ and HINE were useful tools for screening and evaluation of neurodevelopment and neurological function.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2024
Keywords
neurology, rehabilitation, neonatology
National Category
Pediatrics Neurology
Identifiers
urn:nbn:se:uu:diva-525064 (URN)10.1136/bmjpo-2023-002208 (DOI)001175912900002 ()38388007 (PubMedID)
Funder
Karolinska Institute
Available from: 2024-03-21 Created: 2024-03-21 Last updated: 2024-03-21Bibliographically approved
Johansson, M., Fredriksson Kaul, Y., Montgomery, C., Larsson, E., Hellström-Westas, L. & Kochukhova, O. (2023). Different aspects of visual perception are important for 12-year social functioning depending on gestational age. Acta Paediatrica, 112(7), 1537-1547
Open this publication in new window or tab >>Different aspects of visual perception are important for 12-year social functioning depending on gestational age
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2023 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 112, no 7, p. 1537-1547Article in journal (Refereed) Published
Abstract [en]

Aim

Perceptual mechanisms in social functioning might promote interventions. We investigated relations between visual perception and social functioning, in preterm children.

Methods

A prospective preterm cohort born in Uppsala County, Sweden, in 2004–2007 and 49 full-term controls were examined at 12 years. Aspects of visual perception, including static shapes, emotions and time to detect biological motion, were related to social functioning and visual acuity.

Results

The preterm group comprised 25 extremely preterm children, EPT, born below 28 gestational weeks and 53 children born between 28 and 31 weeks. Preterm children had difficulties in perception of static shapes (p = 0.004) and biological motion (p < 0.001), but not in emotion perception, compared to controls. In the EPT children, poorer shape perception and lower scores on emotion perception were associated with more social problems (p = 0.008) and lower visual acuity (p = 0.004). Shape perception explained more variance in social functioning than emotion perception. In controls, fewer social problems were linked to faster biological motion perception (p = 0.04).

Conclusion

Static shape and biological motion perception was affected in the preterm groups. Biological motion perception was relevant for social functioning in full-term children. In EPT children, only shape perception was linked to social functioning, suggesting differential visual perception mechanisms for social deficits.

Place, publisher, year, edition, pages
John Wiley & Sons, 2023
Keywords
autism, Beery visuo-motor integration, biological motion, Social Responsiveness Scale, visual acuity
National Category
Pediatrics Social Psychology
Identifiers
urn:nbn:se:uu:diva-504948 (URN)10.1111/apa.16794 (DOI)000981394100001 ()37073096 (PubMedID)
Funder
Gillbergska stiftelsenSwedish Research Council, 2016/03109Promobilia foundationSamariten foundation for paediatric researchSolstickan FoundationSwedish Research Council, 201603109Linnéa och Josef Carlssons stiftelse
Available from: 2023-06-20 Created: 2023-06-20 Last updated: 2023-06-20Bibliographically approved
Berg, J., Kallen, K., Andolf, E., Hellström-Westas, L., Ekéus, C., Alvan, J. & Vitols, S. (2023). Economic Evaluation of Elective Cesarean Section on Maternal Request Compared With Planned Vaginal Birth-Application to Swedish Setting Using National Registry Data. Value in Health, 26(5), 639-648
Open this publication in new window or tab >>Economic Evaluation of Elective Cesarean Section on Maternal Request Compared With Planned Vaginal Birth-Application to Swedish Setting Using National Registry Data
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2023 (English)In: Value in Health, ISSN 1098-3015, E-ISSN 1524-4733, Vol. 26, no 5, p. 639-648Article in journal (Refereed) Published
Abstract [en]

Objectives: There is a lack of consensus around the definition of delivery by cesarean section (CS) on maternal request, and clinical practice varies across and within countries. Previous economic evaluations have focused on specific populations and selected complications. Our aim was to evaluate the cost-effectiveness of CS on maternal request compared with planned vaginal birth in a Swedish context, based on a systematic review of benefits and drawbacks and national registry data on costs.

Methods: We used the results from a systematic literature review of somatic risks for long-and short-term complications for mother and child, in which certainty was rated low, moderate, or high using the Grading of Recommendations Assessment, Development and Evaluation. Swedish national registry data were used for healthcare costs of delivery and complications. Utilities for long-term complications were based on a focused literature review. We constructed a decision tree and conducted separate analyses for primi-and multiparous women. Costs and effects were discounted by 3% and the time horizon was varied between 1 and 20 years.

Results: Planned vaginal birth leads to lower healthcare costs and somatic health gains compared with elective CS without medical indication over up to 20 years. Although there is uncertainty around, for example, quality-of-life effects, results remain stable across sensitivity analyses.

Conclusions: CS on maternal request leads to increased hospitalization costs in a Swedish setting, taking into account short -and long-term consequences for both mother and child. Future research needs to study the psychological consequences related to different delivery methods, costs in outpatient care, and productivity losses.

Keywords
cesarean section on maternal request, economic evaluation, registry, Sweden, systematic review
National Category
Obstetrics, Gynecology and Reproductive Medicine
Identifiers
urn:nbn:se:uu:diva-504189 (URN)10.1016/j.jval.2022.10.003 (DOI)000992414600001 ()36396536 (PubMedID)
Available from: 2023-06-14 Created: 2023-06-14 Last updated: 2023-06-14Bibliographically approved
El-Dib, M., Abend, N. S. J., Austin, T., Boylan, G., Chock, V., Cilio, M. R., . . . Wusthoff, C. J. (2023). Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures. Pediatric Research, 94(1), 64-73
Open this publication in new window or tab >>Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures
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2023 (English)In: Pediatric Research, ISSN 0031-3998, E-ISSN 1530-0447, Vol. 94, no 1, p. 64-73Article, review/survey (Refereed) Published
Abstract [en]

The blooming of neonatal neurocritical care over the last decade reflects substantial advances in neuromonitoring and neuroprotection. The most commonly used brain monitoring tools in the neonatal intensive care unit (NICU) are amplitude integrated EEG (aEEG), full multichannel continuous EEG (cEEG), and near-infrared spectroscopy (NIRS). While some published guidelines address individual tools, there is no consensus on consistent, efficient, and beneficial use of these modalities in common NICU scenarios. This work reviews current evidence to assist decision making for best utilization of neuromonitoring modalities in neonates with encephalopathy or with possible seizures. Neuromonitoring approaches in extremely premature and critically ill neonates are discussed separately in the companion paper. Impact:center dot Neuromonitoring techniques hold promise for improving neonatal care. center dot For neonatal encephalopathy, aEEG can assist in screening for eligibility for therapeutic hypothermia, though should not be used to exclude otherwise eligible neonates. Continuous cEEG, aEEG and NIRS through rewarming can assist in prognostication. center dot For neonates with possible seizures, cEEG is the gold standard for detection and diagnosis. If not available, aEEG as a screening tool is superior to clinical assessment alone. The use of seizure detection algorithms can help with timely seizures detection at the bedside.

Place, publisher, year, edition, pages
Springer Nature, 2023
National Category
Pediatrics
Identifiers
urn:nbn:se:uu:diva-513061 (URN)10.1038/s41390-022-02393-1 (DOI)000899427900001 ()36476747 (PubMedID)
Available from: 2023-10-13 Created: 2023-10-13 Last updated: 2023-10-13Bibliographically approved
El-Dib, M., Abend, N. S., Austin, T., Boylan, G., Chock, V., Cilio, M. R., . . . Wusthoff, C. J. (2023). Neuromonitoring in neonatal critical care part II: extremely premature infants and critically ill neonates. Pediatric Research, 94(1), 55-63
Open this publication in new window or tab >>Neuromonitoring in neonatal critical care part II: extremely premature infants and critically ill neonates
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2023 (English)In: Pediatric Research, ISSN 0031-3998, E-ISSN 1530-0447, Vol. 94, no 1, p. 55-63Article, review/survey (Refereed) Published
Abstract [en]

Neonatal intensive care has expanded from cardiorespiratory care to a holistic approach emphasizing brain health. To best understand and monitor brain function and physiology in the neonatal intensive care unit (NICU), the most commonly used tools are amplitude-integrated EEG, full multichannel continuous EEG, and near-infrared spectroscopy. Each of these modalities has unique characteristics and functions. While some of these tools have been the subject of expert consensus statements or guidelines, there is no overarching agreement on the optimal approach to neuromonitoring in the NICU. This work reviews current evidence to assist decision making for the best utilization of these neuromonitoring tools to promote neuroprotective care in extremely premature infants and in critically ill neonates. Neuromonitoring approaches in neonatal encephalopathy and neonates with possible seizures are discussed separately in the companion paper. Impact For extremely premature infants, NIRS monitoring has a potential role in individualized brain-oriented care, and selective use of aEEG and cEEG can assist in seizure detection and prognostication. For critically ill neonates, NIRS can monitor cerebral perfusion, oxygen delivery, and extraction associated with disease processes as well as respiratory and hypodynamic management. Selective use of aEEG and cEEG is important in those with a high risk of seizures and brain injury. Continuous multimodal monitoring as well as monitoring of sleep, sleep-wake cycling, and autonomic nervous system have a promising role in neonatal neurocritical care.

Place, publisher, year, edition, pages
Springer Nature, 2023
National Category
Pediatrics
Identifiers
urn:nbn:se:uu:diva-513063 (URN)10.1038/s41390-022-02392-2 (DOI)000888700900002 ()36434203 (PubMedID)
Available from: 2023-10-09 Created: 2023-10-09 Last updated: 2023-10-09Bibliographically approved
Projects
Visual functioning in children born very preterm – relation to cognitive performance, neuromotor function, attention and behavior [2016-03109_VR]; Uppsala UniversityThe role of early visual perception for neurodevelopment in very preterm infants [2020-02636_VR]; Uppsala University
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0003-3498-6069

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