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Brodd, Katarina Strand
Alternative names
Publications (10 of 11) Show all publications
Andersson, A. K., Martin, L., Strand Brodd, K. & Almqvist, L. (2017). Patterns of everyday functioning in preschool children born preterm and at term. Research in Developmental Disabilities, 67, 82-93
Open this publication in new window or tab >>Patterns of everyday functioning in preschool children born preterm and at term
2017 (English)In: Research in Developmental Disabilities, ISSN 0891-4222, E-ISSN 1873-3379, Vol. 67, p. 82-93Article in journal (Refereed) Published
Abstract [en]

Background/Aim: Children born preterm are at risk of neonatal complications but the long-term consequences for everyday functioning is not well known. The study aimed to identify patterns of everyday functioning in preschool children born preterm and at term in relation to perinatal data, neonatal risk factors, behaviour, and socioeconomic status. Registry data and data from parent rated questionnaires were collected for 331 children.

Method: A person-oriented approach with a cluster analysis was used.

Results: A seven cluster solution explained 65.91% of the variance. Most children (n = 232) showed patterns of strong everyday functioning. A minority of the children (n = 99), showed diverse patterns of weak everyday functioning. Perinatal characteristics, neonatal risk factors and socio-economics did not predict cluster group membership. Children born preterm were represented in all clusters.

Conclusion, implications: Most preschool children are perceived by their parents with strong everyday functioning despite being born preterm. However small groups of children are, for various reasons, perceived with weak functioning, but preterm birth is not the sole contributor to patterns of weak everyday functioning. More critical for all children's everyday functioning is probably the interaction between individual factors, behavioural factors and contextual factors. To gain a broader understanding of children's everyday functioning. Child Health Services need to systematically consider aspects of body function, activity and in addition participation and environmental aspects.

Keywords
Everyday functioning, Children born preterm, Child development, Person-oriented research, Cluster analysis
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:uu:diva-332938 (URN)10.1016/j.ridd.2017.06.005 (DOI)000405975900009 ()28651224 (PubMedID)
Available from: 2017-11-15 Created: 2017-11-15 Last updated: 2017-11-15Bibliographically approved
Brodd, K. S. (2017). Replik från Katarina Strand Brodd: Målet är tydliga rutiner för sena aborter [Letter to the editor]. Läkartidningen, 114, Article ID pii: ESZR.
Open this publication in new window or tab >>Replik från Katarina Strand Brodd: Målet är tydliga rutiner för sena aborter
2017 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 114, article id pii: ESZRArticle in journal, Letter (Other academic) Published
National Category
Obstetrics, Gynecology and Reproductive Medicine
Identifiers
urn:nbn:se:uu:diva-346739 (URN)28850164 (PubMedID)
Available from: 2018-03-21 Created: 2018-03-21 Last updated: 2018-03-22Bibliographically approved
Montgomery, C., Hellström-Westas, L., Strand Brodd, K., Sonnander, K. & Persson, K. (2017). The Structured Observation of Motor Performance in Infants has convergent and discriminant validity in preterm and term infants. Acta Paediatrica, 106(5), 740-748
Open this publication in new window or tab >>The Structured Observation of Motor Performance in Infants has convergent and discriminant validity in preterm and term infants
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2017 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 106, no 5, p. 740-748Article in journal (Refereed) Published
Abstract [en]

AIM: Methods are needed to evaluate the level of early motor development and quality of motor performance in infants. We examined the convergent and discriminant validity of the Structured Observation of Motor Performance in Infants (SOMP-I) for evaluating the level of motor development and quality of motor performance in preterm and term infants.

METHODS: A regional cohort of 111 preterm infants with a gestational age of <32 weeks and 72 healthy term born infants were assessed with the SOMP-I, at two, four, six and 10 months of corrected age. Convergent validity was analysed with a mixed model analysis of the motor performance over time. Discriminant validity was analysed with the Mann-Whitney U-test in groups with different neonatal characteristics.

RESULTS: Convergent validity was supported, as the level of motor development increased with age and the quality of motor performance improved over time. The method discriminated for both level and quality between the preterm and the term infants. The preterm infants demonstrated different quality deficits regardless of the level of motor development.

CONCLUSION: Convergent validity and discriminant validity of the SOMP-I were supported in preterm and term infants and facilitates early identification of infants with atypical motor development.

Keywords
Motor development, Motor quality, Preterm infants, Structured Observation of Motor Performance in Infants, Validity
National Category
Pediatrics
Identifiers
urn:nbn:se:uu:diva-318782 (URN)10.1111/apa.13774 (DOI)000398859300010 ()28164371 (PubMedID)
Available from: 2017-03-28 Created: 2017-03-28 Last updated: 2017-05-11Bibliographically approved
Andersson, A. K., Martin, L., Strand Brodd, K. & Almqvist, L. (2016). Predictors for everyday functioning in preschool children born preterm and at term.. Early Human Development, 103, 147-153
Open this publication in new window or tab >>Predictors for everyday functioning in preschool children born preterm and at term.
2016 (English)In: Early Human Development, ISSN 0378-3782, E-ISSN 1872-6232, Vol. 103, p. 147-153Article in journal (Refereed) Published
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-311920 (URN)10.1016/j.earlhumdev.2016.09.011 (DOI)000390973300026 ()27685465 (PubMedID)
Available from: 2017-01-03 Created: 2017-01-03 Last updated: 2017-11-29Bibliographically approved
Kaul, Y. F., Rosander, K., Hofsten, von, C., Brodd, K. S., Holmström, G., Kaul, A., . . . Hellström-Westas, L. (2016). Visual tracking in very preterm infants at 4 months predicts neurodevelopment at 3 years of age. Pediatric Research, 80(1), 35-42
Open this publication in new window or tab >>Visual tracking in very preterm infants at 4 months predicts neurodevelopment at 3 years of age
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2016 (English)In: Pediatric Research, ISSN 0031-3998, E-ISSN 1530-0447, Vol. 80, no 1, p. 35-42Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Typically developing infants track moving objects with eye and head movements in a smooth and predictive way at 4 mo of age, but this ability is delayed in very preterm infants. We hypothesized that visual tracking ability in very preterm infants predicts later neurodevelopment. METHOD: In 67 very preterm infants (gestational age<32wk), eye and head movements were assessed at 4 mo corrected age while the infant tracked a moving object. Gaze gain, smooth pursuit, head movements, and timing of gaze relative the object were analyzed off line. Results of the five subscales included in the Bayley Scales of Infant Development (BSID-III) at 3 y of age were evaluated in relation to the visual tracking data and to perinatal risk factors. RESULTS: Significant correlations were obtained between gaze gain and cognition, receptive and expressive language, and fine motor function, respectively, also after controlling for gestational age, severe brain damage, retinopathy of prematurity, and bronchopulmonary dysplasia. CONCLUSION: This is the first study demonstrating that the basic ability to visually track a moving object at 4 mo robustly predicts neurodevelopment at 3 y of age in children born very preterm.

National Category
Psychology Pediatrics Ophthalmology
Identifiers
urn:nbn:se:uu:diva-284105 (URN)10.1038/pr.2016.37 (DOI)000379377900006 ()27027722 (PubMedID)
Available from: 2016-04-15 Created: 2016-04-15 Last updated: 2017-11-30
Hreinsdottir, J., Ewald, U., Brodd, K. S., Ornkloo, H., von Hofsten, C. & Holmström, G. (2013). Ophthalmological outcome and visuospatial ability in very preterm children measured at 2.5 years corrected age. Acta Paediatrica, 102(12), 1144-1149
Open this publication in new window or tab >>Ophthalmological outcome and visuospatial ability in very preterm children measured at 2.5 years corrected age
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2013 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 102, no 12, p. 1144-1149Article in journal (Refereed) Published
Abstract [en]

AimTo investigate the ophthalmological outcome of very preterm children at 2.5years corrected age (CA) and perform a test of visuospatial and cognitive abilities. MethodsA population-based, prospective study (LOVIS study) in Uppsala County, Sweden, comprised 111 very preterm children (<32 w gestational age [GA]) born between 1 January 2004 and 31 December 2007. Ophthalmic evaluations were undertaken in 98/109 children (89.9%) alive at 2.5 years. Spatial cognition was investigated with a test of five alternative blocks in 48 preterm and 25 term-born children. ResultsVisual impairment, strabismus or refractive errors, were found in 12% of the children. None of the children were blind in both eyes. Logistic regression analyses revealed significant associations between strabismus and periventricular leucomalacia/intraventricular haemorrhage (OR 9.6, p=0.025) and between refractive errors and severe retinopathy of prematurity (OR 9.8, p=0.011) and GA (OR 0.763, p=0.034). Oval and rectangular blocks were significantly more difficult to insert into a box for preterm than full-term children (p=0.048 and 0.013, respectively). There was a significant correlation between total scores for the five blocks and GA at birth (p=0.035). ConclusionEye and visual problems were found in 12% of the preterm children at 30months CA. Preterm children had difficulties with blocks of complex shapes.

Keywords
Ophthalmological outcome, Very preterm children, Visual cognition
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-219208 (URN)10.1111/apa.12406 (DOI)000330040100021 ()
Available from: 2014-02-25 Created: 2014-02-24 Last updated: 2017-12-05Bibliographically approved
Brodd, K. S., Grönqvist, H., Holmström, G., Grönqvist, E., Rosander, K. & Ewald, U. (2012). Development of Smooth Pursuit Eye Movements in very preterm born infants: 3. Association to perinatal risk factors. Acta Paediatrica, 101(2), 164-171
Open this publication in new window or tab >>Development of Smooth Pursuit Eye Movements in very preterm born infants: 3. Association to perinatal risk factors
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2012 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 101, no 2, p. 164-171Article in journal (Refereed) Published
Abstract [en]

Aim:  To investigate the association between perinatal risk factors and neonatal complications and early oculo-motor development in very preterm infants.

Methods:  Perinatal risk factors were identified, and the potential association with early oculo-motor development was evaluated by measuring smooth pursuit eye movements (SP) at 2 and 4 months' corrected age (CA) in a population of very preterm infants born in Uppsala County 2004-2007 (n = 113).

Results:  Among the 15 tested factors, eight showed significant association in univariate analysis with lower levels of SP at 4 months' CA, namely administration of prenatal corticosteroids, gestational age, birthweight, bronchopulmonary dysplasia, retinopathy of prematurity, periventricular leukomalacia, intraventricular haemorrhage >grade 2, and persistent ductus arteriosus. At 2 months' CA, only retinopathy of prematurity >stage 2 was associated with lower levels of SP. When all factors significant in the univariate tests were included in multiple regressions aimed to assess each factor's independent relation to SP, periventricular leukomalacia was the only significant independent factor. When adding 2-5 of the significant factors using multiple regression analysis, the levels of SP became lower.

Conclusion:  Perinatal risk factors were associated with lower levels of SP. This could be interpreted as delayed or disturbed development of normal oculomotor ability.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-155199 (URN)10.1111/j.1651-2227.2011.02449.x (DOI)000298914000021 ()21883450 (PubMedID)
Available from: 2011-06-20 Created: 2011-06-20 Last updated: 2017-12-11Bibliographically approved
Strand Brodd, K. (2011). Delayed Development of Visuomotor Capacity in Very Preterm Infants. (Doctoral dissertation). Uppsala: Acta Universitatis Upsaliensis
Open this publication in new window or tab >>Delayed Development of Visuomotor Capacity in Very Preterm Infants
2011 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

To coordinate visual perception and motor control in daily life where we are constantly surrounded by motion, we are dependent on normal visuomotor capacity. One essential prerequisite for normal visuomotor capacity is smooth pursuit eye movements (SP). Infants born very preterm (VPT = born <32 gestational weeks) are at high risk of developing disabilities in higher brain functions i.e. perception, cognition, concentration and coordination.

In this thesis visuomotor capacity was investigated in a cohort of VPT infants (n = 113) and compared to control groups of full term (FT) infants. Levels of SP were measured at 2 and 4 months’ corrected age (CA). At 8 months’ CA reaching capacity toward a moving object was evaluated as this represents an executive activity guided by vision that develops at an early age.

Lower levels of SP were found in the VPT infants compared to FT controls. The VPT boys showed higher levels of SP compared to the VPT girls.

In VPT infants without major neonatal morbidities lower levels of SP was found compared to the FT controls. No difference in total capacity of gaze tracking was found, although the VPT infants lagged the object more at 4 months’ CA and used more saccades at 2 months’ CA.

With age the VPT infants’ SP levels increased, but with a wider dispersion compared to the FT controls, and the levels of SP at 4 months’ CA corresponded to the levels of the FT infants at 2 months.

 A number of perinatal risk factors were found to be negatively associated to lower levels of SP, and this effect was more pronounced in VPT infants with multiple risk factors,.

 When evaluating the capacity to reach a moving object at 8 months’ CA, the VPT infants showed significantly more bimanual reach and more curved reaching paths to catch the object as compared to the FT control group.

In conclusion, a delayed visuomotor capacity was found in VPT infants compared to FT control infants at 2, 4 and 8 months’ CA. Some VPT infants with perinatal risk factors did not develop in levels of SP between 2 and 4 months’ CA.

 

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2011. p. 58
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 681
Keywords
preterm infants, visual development, neurosensory development, smooth pursuit eye movements, perinatal risk factors, reaching movements
National Category
Pediatrics
Research subject
Pediatrics
Identifiers
urn:nbn:se:uu:diva-156518 (URN)978-91-554-8110-0 (ISBN)
Public defence
2011-09-15, Rosénsalen, Ing 95/96 NBV, Kvinno-och Barndivisionen, Akademiska sjukhuset, Uppsala, 13:00 (Swedish)
Opponent
Supervisors
Available from: 2011-08-25 Created: 2011-07-28 Last updated: 2011-09-08Bibliographically approved
Grönqvist, H., Brodd, K. S. & Rosander, K. (2011). Development of smooth pursuit eye movements in very prematurely born infants: 2. The low-risk subgroup.. Acta Paediatrica, 100(7), e5-e11
Open this publication in new window or tab >>Development of smooth pursuit eye movements in very prematurely born infants: 2. The low-risk subgroup.
2011 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 100, no 7, p. e5-e11Article in journal (Refereed) Published
Abstract [en]

Aim:  To investigate the impact of premature birth on visual tracking in a group of 37 infants, born before the 32nd gestational weeks (mean 29 + 6 weeks) and diagnosed as being without major neonatal complications. This paper is a part of the LOVIS study (Strand Brodd, Ewald, Grönqvist, Holmström, Strömberg, Von Hofsten, et al. Acta Pediatrica, 2011). Methods:  At 2 and 4 months corrected age, eye and head movements were measured when the infant tracked a moving object. The eye movements were analysed in terms of smooth pursuit and saccades (Vision Res, 37, 1997, 1799; Exp Brain Res, 146, 2002, 257). Accuracy of gaze, proportion of smooth pursuit, head movements and saccades were calculated. Results:  Between 2 and 4 months of age, all infants improved their ability to smoothly pursue a moving object. However, at both occasions, the preterm infants had less proportion smooth pursuit than the full-term infants. The groups did not differ with respect to gaze and head movements, but the saccade frequency was higher for the very preterms in some of the conditions. Conclusion:  The development of smooth pursuit in the low-risk preterm infant group was strongly delayed compared to typically developed infants. Thus, the 2 months or more extra visual experience did not have a distinguishable positive effect on visuo-motor development as expressed in smooth pursuit.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-155197 (URN)10.1111/j.1651-2227.2011.02247.x (DOI)000291224200007 ()21362038 (PubMedID)
Note

Manuskriptets titel i avhandlingen: Delayed development of smooth pursuit in very preterm infants with low risk

Available from: 2011-06-20 Created: 2011-06-20 Last updated: 2017-12-11Bibliographically approved
Brodd, K. S., Ewald, U., Grönqvist, H., Holmström, G., Strömberg, B., Grönqvist, E., . . . Rosander, K. (2011). Development of smooth pursuit eye movements in very preterm infants: 1. General aspects. Acta Paediatrica, 100(7), 983-991
Open this publication in new window or tab >>Development of smooth pursuit eye movements in very preterm infants: 1. General aspects
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2011 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 100, no 7, p. 983-991Article in journal (Refereed) Published
Abstract [en]

Aim:  To investigate early oculo-motor development in a population-based cohort of very preterm infants.

Methods:  Early oculo-motor development was prospectively studied by measuring smooth pursuit eye movements at 2 and 4 months corrected age in a population of very preterm infants born in Uppsala County 2004–2007. Eighty-one preterm infants were studied, and 32 healthy term infants constituted the control group.

Results:  The study group consisted of infants with a mean gestational age of28 + 5 weeks. At 2 and 4 months corrected age, infants born very preterm showed lower gain (p < 0.001) and proportion of smooth pursuit eyemovements (p < 0.001) compared to the control group. The boys showed higher gain of smooth pursuit eye movements at both 2 and 4 months corrected age, compared to girls.

Conclusions:  Oculo-motor development measured by smooth pursuit eye movements is delayed in very preterm infants at 2 and 4 months corrected age. This might be a risk factor or early indicator of later perceptual and behavioural impairment.

Keywords
Infant development, Oculo-motor, Preterm infant, Smooth pursuit eye movements
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-155277 (URN)10.1111/j.1651-2227.2011.02218.x (DOI)000291224200025 ()
Note

Titel på manuskript i avhandling: Delayed development of smooth pursuit eye movements in very preterm born infants. A Longitudinal Study of VISuomotor capacity (“LOVIS”)

Available from: 2011-06-20 Created: 2011-06-20 Last updated: 2017-12-11Bibliographically approved
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