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Danielsson, Katarina
Publications (10 of 10) Show all publications
Danielsson, K., Sakarya, A. & Jansson-Fröjmark, M. (2019). The reduced Morningness–Eveningness Questionnaire: Psychometric properties and related factors in a young Swedish population. Chronobiology International, 36(4), 530-540
Open this publication in new window or tab >>The reduced Morningness–Eveningness Questionnaire: Psychometric properties and related factors in a young Swedish population
2019 (English)In: Chronobiology International, ISSN 0742-0528, E-ISSN 1525-6073, Vol. 36, no 4, p. 530-540Article in journal (Refereed) Published
Abstract [en]

During puberty, there is a delay in sleep patterns and the circadian clock, and the prevalence of sleep difficulties is high among young adults. Thus, it is important to be able to measure chronotype (CT) in this group, both in the clinic and for broader epidemiological studies, to better understand the sleep difficulties observed. The reduced version of one of the most widely used questionnaire to measure CT, the Horne & Östberg Morningness–Eveningness Questionnaire (MEQ), has been developed and validated in many languages. The aim of the present study was to investigate the reliability and validity of the Swedish reduced MEQ (rMEQ) and to investigate factors correlated with rMEQ scores in a random sample of young Swedish participants. We sent the rMEQ, sleep questions, demographic questions, the Insomnia Severity Index (ISI), the Epworth Sleepiness Scale, and the Hospital Anxiety and Depression Scale (HADS-A and HADS-D) to 1000 randomly selected individuals aged 16–26 years in Uppsala, Sweden (response rate = 68%). A parallel analysis of the rMEQ revealed a single factor solution. Inter-item correlations within the questionnaire were between 0.08 and 0.46. One of the rMEQ items displayed weak correlations with the other questions. Cronbach’s alpha of the rMEQ was 0.68. Low rMEQ scores (eveningness) were correlated with more frequent late bedtimes and difficulties getting up in the morning. Lower rMEQ scores were significantly related to male sex, no educational activity or work, nicotine use, younger age, and higher ISI and HADS-D scores. Even though the inter-item correlations of the rMEQ were very low to moderate, the rMEQ had a Cronbach’s alpha not far off from acceptable levels, and the strong correlations of the rMEQ scores with responses to the sleep questions indicated that the rMEQ had an adequate validity. To conclude, the rMEQ can be used to effectively estimate CT when a short questionnaire is required; however, caution should be taken when interpreting the results considering the reliability of the questionnaire.

Keywords
Reduced Morningness–Eveningness Questionnaire, chronotype, young adults, adolescents
National Category
Other Health Sciences
Identifiers
urn:nbn:se:uu:diva-372739 (URN)10.1080/07420528.2018.1564322 (DOI)000460047000009 ()30614272 (PubMedID)
Available from: 2019-01-08 Created: 2019-01-08 Last updated: 2019-03-28Bibliographically approved
Danielsson, K., Jansson-Fröjmark, M., Jan-Erik, B. & Markström, A. (2018). Light therapy with scheduled rise times in young adults with delayed sleep phase disorder: Therapeutic outcomes and possible predictors. Behavioural Sleep Medicine, 16(4), 325-336
Open this publication in new window or tab >>Light therapy with scheduled rise times in young adults with delayed sleep phase disorder: Therapeutic outcomes and possible predictors
2018 (English)In: Behavioural Sleep Medicine, ISSN 1540-2002, E-ISSN 1540-2010, Vol. 16, no 4, p. 325-336Article in journal (Refereed) Published
Abstract [en]

Clinical trials with light therapy (LT) for delayed sleep phase disorder (DSPD) are sparse and little is known about factors that are favorable for improvements. In this study, LT with scheduled rise times was conducted at home for 14 days by 44 participants with DSPD aged 16–26 years. Primary outcomes were sleep onset and sleep offset. Potential predictors were demographic characteristics, chronotype, dim light melatonin onset, the number of days the LT lamp was used, the daily duration of LT, daytime sleepiness, anxiety, depression, worry, and rumination. Significant advances were observed in sleep onset and sleep offset from baseline to the end of treatment. The number of days of LT predicted earlier sleep onset and sleep offset.

Place, publisher, year, edition, pages
Taylor & Francis Group, 2018
National Category
Neurosciences Neurology
Identifiers
urn:nbn:se:uu:diva-298760 (URN)10.1080/15402002.2016.1210150 (DOI)000431524200002 ()27712107 (PubMedID)
Available from: 2016-07-07 Created: 2016-07-07 Last updated: 2018-07-04Bibliographically approved
Broman, J.-E., Danielsson, K. & Markström, A. (2016). A Swedish version of the Flinders Fatigue Scale: measurement properties in patients with insomnia disorder. Paper presented at 23rd Congress of the European-Sleep-Research-Society, SEP 13-16, 2016, Bologna, ITALY. Journal of Sleep Research, 25, 346-346
Open this publication in new window or tab >>A Swedish version of the Flinders Fatigue Scale: measurement properties in patients with insomnia disorder
2016 (English)In: Journal of Sleep Research, ISSN 0962-1105, E-ISSN 1365-2869, Vol. 25, p. 346-346Article in journal, Meeting abstract (Other academic) Published
National Category
Neurology
Identifiers
urn:nbn:se:uu:diva-309506 (URN)000383445201429 ()
Conference
23rd Congress of the European-Sleep-Research-Society, SEP 13-16, 2016, Bologna, ITALY
Available from: 2016-12-05 Created: 2016-12-05 Last updated: 2017-11-29Bibliographically approved
Danielsson, K., Jansson-Fröjmark, M., Broman, J.-E. & Agneta, M. (2016). Cognitive behavioral therapy as an adjunct treatment to light therapy for delayed sleep phase disorder in young adults.: A randomized controlled feasibility study. Behavioural Sleep Medicine, 14(2), 212-232
Open this publication in new window or tab >>Cognitive behavioral therapy as an adjunct treatment to light therapy for delayed sleep phase disorder in young adults.: A randomized controlled feasibility study
2016 (English)In: Behavioural Sleep Medicine, ISSN 1540-2002, E-ISSN 1540-2010, Vol. 14, no 2, p. 212-232Article in journal (Refereed) Published
Abstract [en]

Delayed sleep phase disorder (DSPD) is common among young people, but there is still no evidence-based treatment available. In the present study, the feasibility of cognitive behavioral therapy (CBT) was evaluated as an additive treatment to light therapy (LT) in DSPD. A randomized controlled trial with participants aged 16 to 26 years received LT for two weeks followed by either four weeks of CBT or no treatment (NT). LT advanced sleep-wake rhythm in both groups. Comparing LT+CBT with LT+NT, no significant group differences were observed in the primary endpoints. Although anxiety and depression scores were low at pretreatment, they decreased significantly more in LT+CBT compared to LT+NT. The results are discussed and some suggestions are given for further studies.

Place, publisher, year, edition, pages
Taylor & Francis, 2016
National Category
Psychiatry
Research subject
Psychiatry
Identifiers
urn:nbn:se:uu:diva-233847 (URN)10.1080/15402002.2014.981817 (DOI)000371594800008 ()
Available from: 2014-10-10 Created: 2014-10-10 Last updated: 2017-12-05Bibliographically approved
Danielsson, K., Markström, A., Broman, J.-E., von Knorring, L. & Jansson-Fröjmark, M. (2016). Delayed sleep phase disorder in a Swedish cohort of adolescents and young adults: Prevalence and associated factors. Chronobiology International, 33(10), 1331-1339
Open this publication in new window or tab >>Delayed sleep phase disorder in a Swedish cohort of adolescents and young adults: Prevalence and associated factors
Show others...
2016 (English)In: Chronobiology International, ISSN 0742-0528, E-ISSN 1525-6073, Vol. 33, no 10, p. 1331-1339Article in journal (Refereed) Published
Abstract [en]

A delayed sleep-wake and circadian rhythm often occurs during puberty. While some individuals only develop a delayed sleep phase (DSP), others will fulfill the criteria for the diagnosis of delayed sleep phase disorder (DSPD). All previous studies have however not separated DSP from DSPD, and, as a result, the prevalence and associated factors are largely unknown for the two conditions individually. We estimated the prevalence of DSP and DSPD in a Swedish cohort of adolescents and young adults. We also investigated associated factors in the two conditions relative to each other and individuals with no delayed sleep phase. A questionnaire regarding sleep patterns, demographics, substance use/abuse, and symptoms of depression, anxiety, worry, and rumination was sent to 1000 randomly selected participants (16–26 years of age) in Uppsala, Sweden (response rate = 68%). DSP was defined as a late sleep onset and a preferred late wake up time. The DSPD diagnosis was further operationalized according to the Diagnostic and Statistical Manual of Mental Disorders, Edition 5 (DSM-5) criteria including insomnia or excessive sleepiness, distress or dysfunction caused by the delayed sleep phase and that the sleep problem had been evident for 3 months. DSP occurred at a frequency of 4.6% and DSPD at a frequency of 4% in the investigated cohort. DSP was more common in males and was associated with not attending educational activity or work, having shift work, nicotine and alcohol use and less rumination. DSPD was equally common in males and females and was associated with not attending educational activity or work and with elevated levels of anxiety. Both DSP and DSPD appear to be common in adolescents and young adults in this Swedish cohort. No educational activity or work was associated with both DSP and DSPD. However, there were also apparent differences between the two groups in shift work, substance use and mental health, relative to persons with no delayed sleep phase. Thus, it seems reasonable to assess DSP and DSPD as distinct entities in future studies.

Keywords
delayed sleep phase, delayed sleep phase disorder, associated factors, occupational status, shift work, substance use/abuse.
National Category
Neurosciences
Identifiers
urn:nbn:se:uu:diva-298762 (URN)10.1080/07420528.2016.1217002 (DOI)000388746800003 ()27537980 (PubMedID)
Available from: 2016-07-28 Created: 2016-07-07 Last updated: 2018-01-10Bibliographically approved
Danielsson, K. (2016). Delayed Sleep Phase Disorder: Prevalence, Diagnostic aspects, Associated factors and Treatment concepts. (Doctoral dissertation). Uppsala: Acta Universitatis Upsaliensis
Open this publication in new window or tab >>Delayed Sleep Phase Disorder: Prevalence, Diagnostic aspects, Associated factors and Treatment concepts
2016 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Delayed sleep phase disorder (DSPD) is the most common circadian rhythm sleep disorder. Persons with DSPD have great difficulties falling asleep and waking up at conventional times. To diagnose DSPD this delayed sleep-wake rhythm should cause social impairment and distress for the individual. Evening melatonin and morning bright light are the recommended treatments. The overall aim of this thesis was to evaluate at-home treatment with Light therapy (LT) and the feasibility of adding cognitive behavior therapy (CBT) to LT in DSPD, furthermore prevalence, diagnostic aspects and associated factors were investigated.

Study I included 673 randomly selected individuals aged 16–26 years. The prevalence of DSPD was 4.0%. Unemployment (defined as an absence of educational or work activities) and an elevated level of anxiety were associated with DSPD.

In study II, dim light melatonin onset (DLMO) was measured in healthy adults. Time for DLMO DLMO (Mean±SD) was 20:58±55 minutes.

Studies III, IV, and V present results from a randomized controlled trial examining the feasibility of CBT as an additive treatment to LT with scheduled rise times, in persons with DSPD. Sleep onset and sleep offset was significantly advanced from baseline (03:00±1:20; 10:22±2:02 respectively) to the end of LT (01:27±1:41; 08:05±1:29, p<0.001 respectively). This advancement was predicted by consistent daily usage of the LT-lamp. At the follow-ups after LT and CBT or LT alone, sleep onset remained stable, sleep offset was delayed, and sleep difficulties were further improved, but there was no significant group interaction over time. There was a significant group interaction over time in the severity of anxiety and depressive symptoms, both in favor of the LT+CBT group.

Conclusively, DSPD was common among adolescents and young adults and it was associated with unemployment and elevated levels of anxiety. DLMO appeared in the expected time range in healthy working adults. At-home treatment with LT with scheduled rise times advanced sleep-wake rhythm and improved sleep difficulties in DSPD. Even though sleep-wake rhythm was not further advanced or better preserved in the participants that received LT+CBT compared to LT alone, the addition of CBT to the treatment regimen was feasible and well accepted.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2016. p. 70
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 1243
Keywords
delayed sleep phase disorder, prevalence, diagnostic aspects, associated factors, light therapy and cognitive behavior therapy
National Category
Neurosciences
Identifiers
urn:nbn:se:uu:diva-299887 (URN)978-91-554-9645-6 (ISBN)
External cooperation:
Public defence
2016-09-29, Gunnesalen, Akademiska sjukhuset ingång 10, Uppsala, 09:15 (Swedish)
Opponent
Supervisors
Available from: 2016-09-07 Created: 2016-07-29 Last updated: 2018-01-10
Jansson-Fröjmark, M., Danielsson, K., Markström, A. & Jan-Erik, B. (2016). Developing a cognitive behavioral therapy manual for delayed sleep wake phase disorder. Cognitive Behaviour Therapy, 45(6), 518-532
Open this publication in new window or tab >>Developing a cognitive behavioral therapy manual for delayed sleep wake phase disorder
2016 (English)In: Cognitive Behaviour Therapy, ISSN 1650-6073, E-ISSN 1651-2316, Vol. 45, no 6, p. 518-532Article in journal (Refereed) Published
Abstract [en]

This article reports the development of a treatment protocol, based on cognitive behavioral therapy (CBT) principles, for delayed sleep–wake phase disorder (DSWPD). The protocol consists of psycho-education, presenting a CBT model for DSWPD, case formulation, motivational interviewing, registering sleep in a diary, strategies to improve the rhythm of sleep and wakefulness, relaxation training, cognitive restructuring, strategies to cope with daytime symptoms, constructing an individualized CBT program, and learning how to deal with relapses. Qualitative data, focusing on how the patients perceived the protocol, were collected within the realm of a trial exploring the efficacy of the protocol. These findings highlighted several advantages but also disadvantages of the therapy. It is our hope that this paper might act as a platform for further clinical work and future research efforts in patients with DSWPD.

Place, publisher, year, edition, pages
Taylor & Francis Group, 2016
National Category
Neurosciences
Identifiers
urn:nbn:se:uu:diva-298761 (URN)10.1080/16506073.2016.1207096 (DOI)000389240600009 ()
Available from: 2016-07-07 Created: 2016-07-07 Last updated: 2018-01-10Bibliographically approved
Jansson-Fröjmark, M., Danielsson, K., Broman, J.-E. & Markström, A. (2016). The role of coping behaviors in delayed sleep phase syndrome. Paper presented at 23rd Congress of the European-Sleep-Research-Society, SEP 13-16, 2016, Bologna, ITALY. Journal of Sleep Research, 25, 298-298
Open this publication in new window or tab >>The role of coping behaviors in delayed sleep phase syndrome
2016 (English)In: Journal of Sleep Research, ISSN 0962-1105, E-ISSN 1365-2869, Vol. 25, p. 298-298Article in journal, Meeting abstract (Other academic) Published
National Category
Neurology
Identifiers
urn:nbn:se:uu:diva-309499 (URN)000383445201277 ()
Conference
23rd Congress of the European-Sleep-Research-Society, SEP 13-16, 2016, Bologna, ITALY
Available from: 2016-12-05 Created: 2016-12-05 Last updated: 2017-11-29Bibliographically approved
Danielsson, K., Jansson-Frojmark, M., Broman, J.-E. & Markström, A. (2014). Measuring melatonin in saliva before the start of light therapy in delayed sleep phase disorder. Paper presented at 22nd Congress of the European-Sleep-Research-Society, SEP 16-20, 2014, Tallinn, ESTONIA. Journal of Sleep Research, 23, 34-34
Open this publication in new window or tab >>Measuring melatonin in saliva before the start of light therapy in delayed sleep phase disorder
2014 (English)In: Journal of Sleep Research, ISSN 0962-1105, E-ISSN 1365-2869, Vol. 23, p. 34-34Article in journal, Meeting abstract (Other academic) Published
National Category
Neurology
Identifiers
urn:nbn:se:uu:diva-249085 (URN)000349960600082 ()
Conference
22nd Congress of the European-Sleep-Research-Society, SEP 16-20, 2014, Tallinn, ESTONIA
Available from: 2015-04-10 Created: 2015-04-10 Last updated: 2017-12-04Bibliographically approved
Danielsson, K., Markström, A., Stridsberg, M. & Broman, J.-E. (2012). Dim light melatonin onset in normal adults and its relationship with sleep timing and diurnal preference. Biological rhythm research, 43(5), 497-503
Open this publication in new window or tab >>Dim light melatonin onset in normal adults and its relationship with sleep timing and diurnal preference
2012 (English)In: Biological rhythm research, ISSN 0929-1016, E-ISSN 1744-4179, Vol. 43, no 5, p. 497-503Article in journal (Refereed) Published
Abstract [en]

Dim light melatonin onset (DLMO) is defined as the start of the melatonin production in the evening during dim light conditions and has become a reliable phase marker of the circadian clock. The aim of the study was to investigate DLMO and its association with sleep timing and diurnal preferences in healthy working adults during real-life conditions. Fourteen adults were investigated. A sleep diary was kept during the preceding week, but no fixed sleep–wake schedule was implemented. Diurnal preferences were measured with the Horne–O¨ stberg Morningness–Eveningness Questionnaire. DLMO was defined as the time point when melatonin in saliva exceeded a threshold of 3 ng/L. Results showed that DLMO appeared in the expected time interval but was not significantly associated with sleep timing or diurnal preference. The results illustrate the complexity of monitoring sleep patterns in real-life settings.

National Category
Psychiatry
Identifiers
urn:nbn:se:uu:diva-158778 (URN)10.1080/09291016.2011.605631 (DOI)000308443900004 ()
Available from: 2011-09-14 Created: 2011-09-14 Last updated: 2017-12-08Bibliographically approved
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