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Olsson, Roger
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Publications (10 of 13) Show all publications
Tollerz, L. U. U., Forslund, A. H., Olsson, R. M. M., Lidström, H. & Holmbäck, U. (2015). Children with cerebral palsy do not achieve healthy physical activity levels. Acta Paediatrica, 104(11), 1125-1129
Open this publication in new window or tab >>Children with cerebral palsy do not achieve healthy physical activity levels
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2015 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 104, no 11, p. 1125-1129Article in journal (Refereed) Published
Abstract [en]

AimThis study compared daily activity energy expenditure (AEE) in children with cerebral palsy with a control group and investigated whether the children achieved healthy levels of physical activity. MethodsWe enrolled eight children with bilateral cerebral palsy, from eight to 10years of age, and a group of controls matched for age and gender. For three days, physical activity was simultaneously measured by accelerometers and self-reports using a diary. The daily AEE results were compared between groups and methods. The number of children that achieved healthy physical activity levels in each group was explored. ResultsChildren with cerebral palsy had significantly lower daily AEE, as measured by accelerometers, than the controls, and they did not achieve the healthy moderate to heavy physical activity level defined in the Nordic Nutrition Recommendations. Self-reports using the diaries resulted in an overestimation of physical activity compared with the ankle accelerometer measurements in both groups. ConclusionOur investigation of physical activity in children with cerebral palsy and controls using accelerometers and a diary found low levels of daily AEE and physical activity, and these results were most prominent in the group with cerebral palsy. The diaries overestimated physical activity in both groups.

Keywords
Accelerometer, Activity energy expenditure, Cerebral palsy, Children, Physical activity level
National Category
Pediatrics
Identifiers
urn:nbn:se:uu:diva-267657 (URN)10.1111/apa.13141 (DOI)000363866200026 ()
Available from: 2015-11-25 Created: 2015-11-25 Last updated: 2017-12-01Bibliographically approved
Nilsson, B. M., Olsson, R. M., Öman, A., Wiesel, F.-A., Ekselius, L. & Forslund, A. H. (2012). Physical capacity, respiratory quotient and energy expenditure during exercise in male patients with schizophrenia compared with healthy controls. European psychiatry, 27(3), 206-212
Open this publication in new window or tab >>Physical capacity, respiratory quotient and energy expenditure during exercise in male patients with schizophrenia compared with healthy controls
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2012 (English)In: European psychiatry, ISSN 0924-9338, E-ISSN 1778-3585, Vol. 27, no 3, p. 206-212Article in journal (Refereed) Published
Abstract [en]

BACKGROUND

Despite massive research on weight gain and metabolic complications in schizophrenia there are few studies on energy expenditure and no current data on physical capacity. AIM: To determine oxygen uptake capacity, respiratory quotient (RQ) and energy expenditure during a submaximal exercise test in patients with schizophrenia and healthy controls.

METHOD

Ten male patients and 10 controls were included. RQ and energy expenditure were investigated with indirect calorimetry during a cycle ergometer test. The submaximal work level was defined by heart rate and perceived exhaustion. Physical capacity was determined from predicted maximal oxygen uptake capacity (VO(2-max)).

RESULTS

The patients exhibited significantly higher RQ on submaximal workloads and lower physical capacity. A significant lower calculated VO(2-max) remained after correction for body weight and fat free mass (FFM). Energy expenditure did not differ on fixed workloads.

CONCLUSION

RQ was rapidly increasing in the patients during exercise indicating a faster transition to carbohydrate oxidation and anaerobic metabolism that also implies a performance closer to maximal oxygen uptake even at submaximal loads. This may restrict the capacity for everyday activity and exercise and thus contribute to the risk for weight gain. Physical capacity was consequently significantly lower in the patients.

Keywords
Schizophrenia, Physical capacity, Respiratory quotient, Oxygen uptakecapacity, Energy expenditure, Body weight
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-138990 (URN)10.1016/j.eurpsy.2010.06.007 (DOI)000302516500008 ()20970966 (PubMedID)
Available from: 2010-12-21 Created: 2010-12-21 Last updated: 2017-12-11Bibliographically approved
Hallin, R., Janson, C., Arnardottir, H., Olsson, R., Emtner, M., Branth, S., . . . Slinde, F. (2011). Relation between physical capacity, nutritional status and systemic inflammation in COPD. Clinical Respiratory Journal, 5(3), 136-142
Open this publication in new window or tab >>Relation between physical capacity, nutritional status and systemic inflammation in COPD
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2011 (English)In: Clinical Respiratory Journal, ISSN 1752-6981, E-ISSN 1752-699X, Vol. 5, no 3, p. 136-142Article in journal (Refereed) Published
Abstract [en]

Background: Decreased physical capacity, weight loss, fat-free mass depletion and systemic inflammation are frequently observed in patients with chronic obstructive pulmonary disease (COPD).

Objective: Our aim was to examine relations between physical capacity, nutritional status, systemic inflammation and disease severity in COPD.

Method: Forty nine patients with moderate to severe COPD were included in the study. Spirometry was preformed. Physical capacity was determined by a progressive symptom limited cycle ergo meter test, incremental shuttle walking test, 12-minute walk distance and hand grip strength test. Nutritional status was investigated by anthropometric measurements, (weight, height, arm and leg circumferences and skinfold thickness) and bioelectrical impedance assessment was performed. Blood samples were analyzed for C-reactive protein (CRP) and fibrinogen.

Result: Working capacity was positively related to forced expiratory volume in 1 s (FEV(1)) (p < 0.001), body mass index and fat free mass index (p = 0.01) and negatively related to CRP (p = 0.02) and fibrinogen (p = 0.03). Incremental shuttle walk test was positively related to FEV(1) (p < 0.001) and negatively to CRP (p = 0.048). Hand grip strength was positively related to fat free mass index, and arm and leg circumferences. Fifty to 76% of the variation in physical capacity was accounted for when age, gender, FEV(1), fat free mass index and CRP were combined in a multiple regression model.

Conclusion: Physical capacity in chronic obstructive pulmonary disease is related to lung function, body composition and systemic inflammation. A depiction of all three aspects of the disease might be important when targeting interventions in chronic obstructive pulmonary disease.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-97938 (URN)10.1111/j.1752-699X.2010.00208.x (DOI)000292361500004 ()
Available from: 2008-12-22 Created: 2008-12-22 Last updated: 2017-12-14Bibliographically approved
Bratteby Tollerz, L. U., Olsson, R. M., Forslund, A. H. & Norrlin, S. E. (2011). Reliability of energy cost calculations in children with cerebral palsy, cystic fibrosis and healthy controls. Acta Paediatrica, 100(12), 1616-1620
Open this publication in new window or tab >>Reliability of energy cost calculations in children with cerebral palsy, cystic fibrosis and healthy controls
2011 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 100, no 12, p. 1616-1620Article in journal (Refereed) Published
Abstract [en]

Aim: To study test-retest reliability of physiological cost index (PCI) and total cost index (TCI) in three groups of children. TCI modified PCI by excluding rest heart rate in calculation.

Methods: Energy cost was evaluated from two consecutive walking tests, and results were compared between methods, tests and groups. Thirty-nine children, eight with cerebral palsy, 11 with cystic fibrosis and 20 healthy controls, aged 5-16 years participated in the study conducted at the Clinical Nutrition and Metabolism laboratory, University Hospital, Uppsala, Sweden. Heart rate was recorded during sitting and walking at self-selected speed. PCI and TCI were calculated using both non-steady-state and steady-state work heart rates. Test-retest reliability was analysed by mean of differences, pooled SD, coefficient of variation (CV%) and correlation coefficients.

Results: Reliability was high for PCI and TCI. TCI showed consistently lower variation between tests than PCI for all groups. In the group with cerebral palsy, using non-steady-state showed highest reliability.

Conclusion: Both PCI and TCI were reliable methods when calculating energy cost in children with cerebral palsy, cystic fibrosis and controls. TCI seemed to be a suitable alternative in the evaluation of gait efficiency in children.

National Category
Health Sciences Physiotherapy Neurology
Identifiers
urn:nbn:se:uu:diva-162981 (URN)10.1111/j.1651-2227.2011.02396.x (DOI)000296899500027 ()21726284 (PubMedID)
Available from: 2011-12-06 Created: 2011-12-06 Last updated: 2017-12-08Bibliographically approved
Branth, S., Hambraeus, L., Piehl-Aulin, K., Essén-Gustavsson, B., Åkerfeldt, T., Olsson, R., . . . Ronquist, G. (2009). Metabolic stress-like condition can be induced by prolonged strenuous exercise in athletes. Upsala Journal of Medical Sciences, 114(1), 12-25
Open this publication in new window or tab >>Metabolic stress-like condition can be induced by prolonged strenuous exercise in athletes
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2009 (English)In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 114, no 1, p. 12-25Article in journal (Refereed) Published
Abstract [en]

Few studies have examined energy metabolism during prolonged, strenuous exercise. We wanted therefore to investigate energy metabolic consequences of a prolonged period of continuous strenuous work with very high energy expenditure. Twelve endurance-trained athletes (6 males and 6 females) were recruited. They performed a 7-h bike race on high work-load intensity. Physiological, biochemical, endocrinological, and anthropometric muscular compartment variables were monitored before, during, and after the race. The energy expenditure was high, being 5557 kcal. Work-load intensity (% of VO2 peak) was higher in females (77.7%) than in men (69.9%). Muscular glycogen utilization was pronounced, especially in type I fibres (>90%). Additionally, muscular triglyceride lipolysis was considerably accelerated. Plasma glucose levels were increased concomitantly with an unchanged serum insulin concentration which might reflect an insulin resistance state in addition to proteolytic glyconeogenesis. Increased reactive oxygen species (malondialdehyde (MDA)) were additional signs of metabolic stress. MDA levels correlated with glycogen utilization rate. A relative deficiency of energy substrate on a cellular level was indicated by increased intracellular water of the leg muscle concomitantly with increased extracellular levels of the osmoregulatory amino acid taurine. A kindred nature of a presumed insulin-resistant state with less intracellular availability of glucose for erythrocytes was also indicated by the findings of decreased MCV together with increased MCHC (haemoconcentration) after the race. This strenuous energy-demanding work created a metabolic stress-like condition including signs of insulin resistance and deteriorated intracellular glucose availability leading to compromised fuelling of ion pumps, culminating in a disturbed cellular osmoregulation indicated by taurine efflux and cellular swelling.

Keywords
Cellular swelling, energy expenditure, lipid peroxidation, metabolism, myocytes, taurine efflux
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-120869 (URN)10.1080/03009730802579778 (DOI)000263095500003 ()19242868 (PubMedID)
Available from: 2010-03-16 Created: 2010-03-16 Last updated: 2017-12-12Bibliographically approved
Branth, S., Ronquist, G., Stridsberg, M., Hambraeus, L., Kindgren, E., Olsson, R., . . . Arnetz, B. (2007). Development of abdominal fat and incipient metabolic syndrome in young healthy men exposed to long-term stress. NMCD. Nutrition Metabolism and Cardiovascular Diseases, 17(6), 427-435
Open this publication in new window or tab >>Development of abdominal fat and incipient metabolic syndrome in young healthy men exposed to long-term stress
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2007 (English)In: NMCD. Nutrition Metabolism and Cardiovascular Diseases, ISSN 0939-4753, E-ISSN 1590-3729, Vol. 17, no 6, p. 427-435Article in journal (Refereed) Published
Abstract [en]

BACKGROUND AND AIM: The sympathetic nervous system may be involved in the pathophysiology of insulin resistance and metabolic cardiovascular syndrome in young men. The aim was to study the effects of long-term stress on different features of the metabolic syndrome (MES) in formerly non-obese healthy young males during 5 months of defined conditions. METHODS AND RESULTS: Sixteen healthy male sailors (mean age 36.5 (SD)+/-7 years) participating in a sailing race around the world were recruited for the study. Investigations were done before the start and at stop overs after finishing laps 1, 2 and 4 (1, 2(1/2) and 5 months, respectively). Anthropometric and blood pressure data as well as biochemical data associated with MES were substantiated. Food intake and exercise were chartered and largely controlled. A mean weight loss of 4.5+/-2 kg (P<0.005), comprising both fat and lean body mass, was recorded during the first lap. Subsequently after 5 months, a weight gain, mainly consisting of 1.2+/-1.1 kg body fat (P<0.05), took place, concomitantly with a protein mass drop of 0.6+/-1.1 kg (P<0.05). The body fat gain accumulated on the abdominal region. Elevated blood levels of HbA1c, insulin and the triglycerides/high-density lipoprotein ratio were also observed during the race. Likewise heart rate and systolic blood pressure increased slightly but to a statistically significant extent. CONCLUSIONS: Non-obese healthy young men exposed to long-term stress developed abdominal obesity and signs of a metabolic syndrome in embryo, also emphasized by biochemical and blood pressure alterations. It is suggested that long-term and sustained stress activation might be an additional risk factor for the development of MES, even after control of dietary and exercise habits.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-15959 (URN)10.1016/j.numecd.2006.03.001 (DOI)000249711700003 ()17134957 (PubMedID)
Available from: 2008-04-15 Created: 2008-04-15 Last updated: 2017-12-08Bibliographically approved
Omarsdottir, S., Ljunggren, O., Mallmin, H., Olsson, R., Prytz, H. & Lööf, L. (2002). Longitudinal bone loss in postmenopausal women with primary biliary cirrhosis and well-preserved liver function.. J Intern Med, 252(6), 537-41
Open this publication in new window or tab >>Longitudinal bone loss in postmenopausal women with primary biliary cirrhosis and well-preserved liver function.
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2002 (English)In: J Intern Med, ISSN 0954-6820, Vol. 252, no 6, p. 537-41Article in journal (Refereed) Published
Keywords
Adult, Aged, Bone Density, Female, Femur Neck, Hormone Replacement Therapy/methods, Humans, Liver Cirrhosis; Biliary/*complications/physiopathology, Lumbar Vertebrae, Middle Aged, Osteoporosis; Postmenopausal/*etiology/physiopathology, Retrospective Studies
Identifiers
urn:nbn:se:uu:diva-74873 (URN)12472915 (PubMedID)
Available from: 2008-06-15 Created: 2008-06-15 Last updated: 2011-01-13
Andersson, A., Sjödin, A., Hedman, A., Olsson, R. & Vessby, B. (2000). Fatty acid profile of skeletal muscle phospholipids in trained and untrained young men. American Journal of Physiology. Endocrinology and Metabolism, 279(4), E744-E751
Open this publication in new window or tab >>Fatty acid profile of skeletal muscle phospholipids in trained and untrained young men
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2000 (English)In: American Journal of Physiology. Endocrinology and Metabolism, ISSN 0193-1849, E-ISSN 1522-1555, Vol. 279, no 4, p. E744-E751Article in journal (Refereed) Published
Abstract [en]

Endurance trained (n = 14) and untrained young men (n = 15) were compared regarding the fatty acid profile of the vastus lateralis muscle after 8 wk on diets with a similar fatty acid composition. The skeletal muscle phospholipids in the trained group contained lower proportions of palmitic acid (16:0) (-12.4%, P < 0.001) and di-homo-gamma-linolenic acid [20:3(n-6)] (-15.3%, P = 0.018), a lower n-6-to-n-3 ratio (-42.0%, P = 0.015), higher proportions of stearic acid (18:0) (+9.8%, P = 0.004) and sum of n-3 polyunsaturated fatty acids (+33.8%, P = 0.009), and a higher ratio between 20:4(n-6) to 20:3(n-6) (+18.4%, P = 0.006) compared with those in the untrained group. The group differences in 16:0, 20:3(n-6), 18:0/16:0, and 20:4(n-6)/20:3(n-6) were independent of fiber-type distribution. The trained group also showed a lower proportion of 16:0 (-7.9%, P < 0.001) in skeletal muscle triglycerides irrespective of fiber type. In conclusion, the fatty acid profile of the skeletal muscle differed between trained and untrained individuals, although the dietary fatty acid composition was similar. This difference was not explained by different fiber-type distribution alone but appears to be a direct consequence of changes in fatty acid metabolism due to the higher level of physical activity.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:uu:diva-89437 (URN)11001754 (PubMedID)
Available from: 2001-09-19 Created: 2001-09-19 Last updated: 2017-12-14Bibliographically approved
Andersson, A., Sjödin, A., Hedman, A., Olsson, R. & Vessby, B. (1999). Fatty acid profile of skeletal muscle phospholipids in trained and undtrained young men.. In: 8th European Nutrition Conference, Lillehammer, Norge 17-19 juni, 1999.: Scand. J. Nutr. 73S, suppl 34, 2/1999.
Open this publication in new window or tab >>Fatty acid profile of skeletal muscle phospholipids in trained and undtrained young men.
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1999 (English)In: 8th European Nutrition Conference, Lillehammer, Norge 17-19 juni, 1999.: Scand. J. Nutr. 73S, suppl 34, 2/1999, 1999Conference paper, Published paper (Other (popular scientific, debate etc.))
Identifiers
urn:nbn:se:uu:diva-18457 (URN)
Available from: 2006-12-21 Created: 2006-12-21
Andersson, A., Hedman, A., Olsson, R., Sjödin, A. & Vessby, B. (1999). Skelettmuskelns fettsyraprofil i relation till fysisk aktivitet, dietärt fett och fibertyp. In: Svenska Läkarsällskapets Riksstämma 30 nov-2dec, 1999.
Open this publication in new window or tab >>Skelettmuskelns fettsyraprofil i relation till fysisk aktivitet, dietärt fett och fibertyp
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1999 (Swedish)In: Svenska Läkarsällskapets Riksstämma 30 nov-2dec, 1999, 1999Conference paper, Published paper (Other (popular scientific, debate etc.))
Identifiers
urn:nbn:se:uu:diva-18456 (URN)
Available from: 2006-12-21 Created: 2006-12-21
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