uu.seUppsala universitets publikasjoner
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Reply to Caetano-Anolles et al. comment on "Empirical genome evolution models root the tree of life"
Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för cell- och molekylärbiologi, Strukturbiologi.ORCID-id: 0000-0001-7468-7317
Lund Univ, Dept Biol, Lund, Sweden.
2018 (engelsk)Inngår i: Biochimie, ISSN 0300-9084, E-ISSN 1638-6183, Vol. 149, s. 137-138Artikkel i tidsskrift, Letter (Annet vitenskapelig) Published
Abstract [en]

We recently analyzed the robustness of competing evolution models developed to identify the root of the Tree of Life: 1) An empirical Sankoff parsimony (ESP) model (Harish and Kurland, 2017), which is a nonstationary and directional evolution model; and 2) An a priori ancestor (APA) model (Kim and Caetano-Anolles, 2011) that is a stationary and reversible evolution model. Both Bayesian model selection tests as well as maximum parsimony analyses demonstrate that the ESP model is, overwhelmingly, the better model. Moreover, we showed that the APA model is not only sensitive to artifacts, but also that the underlying assumptions are neither empirically grounded nor biologically realistic.

sted, utgiver, år, opplag, sider
2018. Vol. 149, s. 137-138
Emneord [en]
Evolution, Phylogenomics, Proteome, Selection, Tree of life
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-362652DOI: 10.1016/j.biochi.2018.04.002ISI: 000434053100015PubMedID: 29631014OAI: oai:DiVA.org:uu-362652DiVA, id: diva2:1256107
Tilgjengelig fra: 2018-10-16 Laget: 2018-10-16 Sist oppdatert: 2018-10-16bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekstPubMed

Personposter BETA

Harish, Ajith

Søk i DiVA

Av forfatter/redaktør
Harish, Ajith
Av organisasjonen
I samme tidsskrift
Biochimie

Søk utenfor DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 99 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf