uu.seUppsala universitets publikasjoner
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Advances in mass spectrometry based single-cell metabolomics
Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Kemiska sektionen, Institutionen för kemi - BMC, Analytisk kemi.ORCID-id: 0000-0003-0575-0858
Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Kemiska sektionen, Institutionen för kemi - BMC, Analytisk kemi.
Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Kemiska sektionen, Institutionen för kemi - BMC, Analytisk kemi.ORCID-id: 0000-0001-9040-3230
2019 (engelsk)Inngår i: The Analyst, ISSN 0003-2654, E-ISSN 1364-5528, Vol. 144, nr 3, s. 782-793Artikkel, forskningsoversikt (Fagfellevurdert) Published
Abstract [en]

Metabolomics has grown into a prominent field contributing to the molecular understanding of complex biological processes in both health and disease. Furthermore, single-cells are known to display metabolic differences between seemingly homogeneous populations of cells. Single-cell metabolomics attempts to analyze many cellular metabolites from single cells to understand phenotypic heterogeneity, which is a significant challenge due to the low analyte abundances and limited sample volumes. Label-free metabolite detection can be achieved with mass spectrometry, which is capable of simultaneously analyzing hundreds of metabolites. Herein, we review the recent advances in mass spectrometry based single-cell metabolomics, highlighting the current state-of-the-art within the last three years, and identify the challenges to move the field forward.

sted, utgiver, år, opplag, sider
ROYAL SOC CHEMISTRY , 2019. Vol. 144, nr 3, s. 782-793
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-377492DOI: 10.1039/c8an01581cISI: 000457394400004PubMedID: 30426983OAI: oai:DiVA.org:uu-377492DiVA, id: diva2:1290458
Forskningsfinansiär
Swedish Foundation for Strategic Research Swedish Research CouncilTilgjengelig fra: 2019-02-20 Laget: 2019-02-20 Sist oppdatert: 2019-02-20bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekstPubMed

Personposter BETA

Duncan, Kyle D.Lanekoff, Ingela

Søk i DiVA

Av forfatter/redaktør
Duncan, Kyle D.Fyrestam, JonasLanekoff, Ingela
Av organisasjonen
I samme tidsskrift
The Analyst

Søk utenfor DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 68 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf