Genome-wide association study identified novel candidate loci affecting wood formation in Norway spruceUniv Helsinki, Dept Biosci, Ecol Genet Res Unit, POB 65, FI-00014 Helsinki, Finland.
Univ Oulu, Dept Math Sci, Bioctr Oulu, Pentti Kaiteran Katu 1, Oulu, Finland.
Swedish Univ Agr Sci, Dept Forest Genet & Plant Physiol, Umea Plant Sci Ctr, Parallellvagen 21, S-90736 Umea, Sweden;Umea Univ, Dept Ecol & Environm Sci, Linnaeus Vag 4-6, S-90736 Umea, Sweden.
Swedish Univ Agr Sci, Dept Forest Genet & Plant Physiol, Umea Plant Sci Ctr, Parallellvagen 21, S-90736 Umea, Sweden.
RISE Bioecon, Drottning Kristinas Vag 61, SE-11486 Stockholm, Sweden.
RISE Bioecon, Drottning Kristinas Vag 61, SE-11486 Stockholm, Sweden.
Skogforsk, Ekebo 2250, SE-26890 Svalov, Sweden.
Swedish Univ Agr Sci, Dept Forest Genet & Plant Physiol, Umea Plant Sci Ctr, Parallellvagen 21, S-90736 Umea, Sweden.
Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Evolutionsbiologi. Umea Univ, Dept Ecol & Environm Sci, Linnaeus Vag 4-6, S-90736 Umea, Sweden.
RISE Bioecon, Drottning Kristinas Vag 61, SE-11486 Stockholm, Sweden;IIC, Rosenlundsgatan 48B, SE-11863 Stockholm, Sweden.
Swedish Univ Agr Sci, Dept Forest Genet & Plant Physiol, Umea Plant Sci Ctr, Parallellvagen 21, S-90736 Umea, Sweden.
Swedish Univ Agr Sci, Dept Forest Genet & Plant Physiol, Umea Plant Sci Ctr, Parallellvagen 21, S-90736 Umea, Sweden.
Vise andre og tillknytning
2019 (engelsk)Inngår i: The Plant Journal, ISSN 0960-7412, E-ISSN 1365-313X, Vol. 100, nr 1, s. 83-100Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]
Norway spruce is a boreal forest tree species of significant ecological and economic importance. Hence there is a strong imperative to dissect the genetics underlying important wood quality traits in the species. We performed a functional genome-wide association study (GWAS) of 17 wood traits in Norway spruce using 178 101 single nucleotide polymorphisms (SNPs) generated from exome genotyping of 517 mother trees. The wood traits were defined using functional modelling of wood properties across annual growth rings. We applied a Least Absolute Shrinkage and Selection Operator (LASSO-based) association mapping method using a functional multilocus mapping approach that utilizes latent traits, with a stability selection probability method as the hypothesis testing approach to determine a significant quantitative trait locus. The analysis provided 52 significant SNPs from 39 candidate genes, including genes previously implicated in wood formation and tree growth in spruce and other species. Our study represents a multilocus GWAS for complex wood traits in Norway spruce. The results advance our understanding of the genetics influencing wood traits and identifies candidate genes for future functional studies.
sted, utgiver, år, opplag, sider
WILEY , 2019. Vol. 100, nr 1, s. 83-100
Emneord [en]
candidate genes, functional trait mapping, genome-wide association mapping, Norway spruce, sequence capture, single nucleotide polymorphisms
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-396127DOI: 10.1111/tpj.14429ISI: 000478331500001PubMedID: 31166032OAI: oai:DiVA.org:uu-396127DiVA, id: diva2:1366759
Forskningsfinansiär
Knut and Alice Wallenberg FoundationThe Kempe Foundations2019-06-052019-10-302019-11-04bibliografisk kontrollert