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Luteal phase progesterone increases live birth rate after frozen embryo transfer
Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm.
Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm.
Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm.
Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Obstetrik & gynekologi. (Klinisk och experimentell reproduktionsbiologi/Olovsson)
2011 (engelsk)Inngår i: Fertility and Sterility, ISSN 0015-0282, E-ISSN 1556-5653, Vol. 95, nr 2, s. 534-537Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

OBJECTIVE: To see if progesterone support has a beneficial effect on live birth rate after frozen embryo transfer in natural cycles. DESIGN: Prospective randomized controlled trial. SETTING: University-based hospital. SUBJECT(S): Four hundred thirty-five women undergoing embryo transfer in natural cycles. INTERVENTION(S): The women received either vaginal progesterone, 400 mg twice a day from the day of embryo transfer in natural cycles, or no progesterone support. MAIN OUTCOME MEASURE(S): Live birth rate, biochemical pregnancy rate, pregnancy rate, and spontaneous abortion rate. RESULT(S): Live birth rate were significantly greater in women receiving vaginal progesterone as luteal phase support after frozen-thawed embryo transfer in natural cycles compared with those who did not take progesterone. There were no differences in biochemical pregnancy rate, pregnancy rate, or spontaneous abortion rate. CONCLUSION(S): Progesterone supplementation improves live birth rate after embryo transfer in natural cycles.

sted, utgiver, år, opplag, sider
2011. Vol. 95, nr 2, s. 534-537
Emneord [en]
frozen embryo transfer, live birth rate, natural menstrual cycle, pregnancy rate, Progesterone
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-140104DOI: 10.1016/j.fertnstert.2010.05.019ISI: 000286419000023PubMedID: 20579989OAI: oai:DiVA.org:uu-140104DiVA, id: diva2:382936
Tilgjengelig fra: 2011-01-03 Laget: 2011-01-03 Sist oppdatert: 2017-12-11bibliografisk kontrollert

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