uu.seUppsala universitets publikasjoner
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Randomized comparison of the influence of dietary management and/or physical exercise on ovarian function and metabolic parameters in overweight women with polycystic ovary syndrome
Vise andre og tillknytning
2011 (engelsk)Inngår i: Fertility and Sterility, ISSN 0015-0282, E-ISSN 1556-5653, Vol. 96, nr 6, 1508-1513 s.Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Objective:

To compare the influence of dietary management and/or physical exercise on ovarian function and metabolic variables in women with polycystic ovary syndrome (PCOS).

Design:

Randomized 4-month trial with three interventions and a long-term follow-up.

Setting:

Women's health clinical research unit at a university hospital.

Patient(s):

Fifty-seven overweight/obese women with PCOS.

Intervention(s):

Dietary management, physical exercise, or both, using programs individually adapted and supervised by a dietician and/or a physical therapist. Main

Outcome Measure(s):

Ovarian function, endocrinologic, and metabolic status and body composition.

Result(s):

On average, body mass index was reduced 6% by the dietary management, 3% by the exercise, and 5% by the combined interventions. Lower body fat and lean body mass were significantly decreased in the dietary groups, whereas upper body fat was lowered and lean body mass maintained by exercise alone. The menstrual pattern was significantly improved in 69% and ovulation confirmed in 34% of the patients, with no differences among the groups. The strongest predictor of resumed ovulation was a high serum level of insulin-like growth factor-binding protein 1 after the intervention. Follow-up of one-half of the patients for a median of 2.8 years revealed sustained weight reduction and improvement in menstrual pattern.

Conclusion(s):

Dietary management and exercise, alone or in combination, are equally effective in improving reproductive function in overweight/obese women with PCOS. The underlying mechanisms appear to involve enhanced insulin sensitivity. Supportive individualized programs for lifestyle change could exert long-term beneficial effects.

sted, utgiver, år, opplag, sider
2011. Vol. 96, nr 6, 1508-1513 s.
Emneord [en]
PCOS, obesity, diet, physical activity, lifestyle intervention, ovulation, body composition, weight loss
HSV kategori
Forskningsprogram
Medicinsk vetenskap
Identifikatorer
URN: urn:nbn:se:uu:diva-168414DOI: 10.1016/j.fertnstert.2011.09.006ISI: 000298119700050OAI: oai:DiVA.org:uu-168414DiVA: diva2:499274
Tilgjengelig fra: 2012-02-13 Laget: 2012-02-10 Sist oppdatert: 2017-12-07bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler

Andre lenker

Forlagets fulltekst

Personposter BETA

Hellström, Per Martin

Søk i DiVA

Av forfatter/redaktør
Hellström, Per Martin
Av organisasjonen
I samme tidsskrift
Fertility and Sterility

Søk utenfor DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric

doi
urn-nbn
Totalt: 398 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf