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Ethical issues raised by whole genome sequencing
Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Centrum för forsknings- och bioetik.
2014 (engelsk)Inngår i: Baillière's Best Practice & Research: Clinical Gastroenterology, ISSN 1521-6918, E-ISSN 1532-1916, Vol. 28, nr 2, s. 269-279Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

While there is ongoing discussion about the details of implementation of whole genome sequencing (WGS) and whole exome sequencing (WES), there appears to be a consensus amongst geneticists that the widespread use of these approaches is not only inevitable, but will also be beneficial [1]. However, at the present time, we are unable to anticipate the full range of uses, consequences and impact of implementing WGS and WES. Nevertheless, the already known ethical issues, both in research and in clinical practice are diverse and complex and should be addressed properly presently. Herein, we discuss the ethical aspects of WGS and WES by particularly focussing on three overlapping themes: (1) informed consent, (2) data handling, and (3) the return of results.

sted, utgiver, år, opplag, sider
2014. Vol. 28, nr 2, s. 269-279
Emneord [en]
Medical ethics, Next generation sequencing, Whole genome sequencing
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-228055DOI: 10.1016/j.bpg.2014.02.004ISI: 000336705600006OAI: oai:DiVA.org:uu-228055DiVA, id: diva2:732311
Tilgjengelig fra: 2014-07-03 Laget: 2014-07-03 Sist oppdatert: 2017-12-05bibliografisk kontrollert

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