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Mechanisms of carbon fixation and engineering for increased carbon fixation in cyanobacteria
Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Kemiska sektionen, Institutionen för kemi - Ångström, Molekylär biomimetik.
Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Kemiska sektionen, Institutionen för kemi - Ångström, Molekylär biomimetik.
2015 (engelsk)Inngår i: ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, ISSN 2211-9264, Vol. 11, s. 263-270Artikkel, forskningsoversikt (Fagfellevurdert) Published
Abstract [en]

Cyanobacteria, gram-negative prokaryotic microorganisms, perform oxygenic photosynthesis with a photosynthetic machinery similar to higher plants which includes ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCO) as the main CO2-fixing enzyme. Currently, there is a growing interest to use cyanobacteria as photosynthetic microbial cell factories for the direct production of solar fuels or other compounds of human interest. However, rates and efficiencies to produce e.g. biofuels are still very low. The amount of available fixed carbon for the synthesis of desired product(s) may be one of the limiting steps. This contribution reviews CO2-fixation in cyanobacteria with focus on CO2-concentrating mechanisms, RuBisCO, phosphoenolpyruvate carboxylase and other carboxylases, engineering approaches for increased carbon fixation, and finally the synthetic malonyl-CoA-oxaloacetate-glyoxylate pathways.

sted, utgiver, år, opplag, sider
2015. Vol. 11, s. 263-270
Emneord [en]
Carbon fixation, Cyanobacteria, Genetic engineering, MOG pathway, PEPc, RuBisCO, Synechocystis PCC 6803
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Identifikatorer
URN: urn:nbn:se:uu:diva-267607DOI: 10.1016/j.algal.2015.07.002ISI: 000363046900033OAI: oai:DiVA.org:uu-267607DiVA, id: diva2:873820
Forskningsfinansiär
Swedish Research CouncilKnut and Alice Wallenberg FoundationTilgjengelig fra: 2015-11-25 Laget: 2015-11-25 Sist oppdatert: 2016-02-23bibliografisk kontrollert

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