uu.seUppsala universitets publikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Association between childhood adversity and a diagnosis of personality disorder in young adulthood: a cohort study of 107,287 individuals in Stockholm County
Karolinska Inst, Div Social Med, Dept Publ Hlth Sci, Stockholm, Sweden.;Univ Calif Los Angeles, Fielding Sch Publ Hlth, Calif Ctr Populat Res, Dept Community Hlth Sci, Los Angeles, CA 90095 USA..
Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Psykiatri, Akademiska sjukhuset.
Karolinska Inst, Div Social Med, Dept Publ Hlth Sci, Stockholm, Sweden..
Karolinska Inst, Div Publ Hlth Epidemiol, Dept Publ Hlth Sci, Stockholm, Sweden.;Stockholm Cty Council, Ctr Epidemiol & Community Med, Stockholm, Sweden..
Visa övriga samt affilieringar
2017 (Engelska)Ingår i: European Journal of Epidemiology, ISSN 0393-2990, E-ISSN 1573-7284, Vol. 32, nr 8, s. 721-731Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Childhood adversity (CA) may increase the risk for later developing of personality disorder (PD). However, less is known about the association between cumulative CA and PD, and the role of childhood psychopathology and school performance. The current study examined the relationship between a range of CAs and a diagnosis of PD in young adulthood, and the roles of childhood psychopathology and school performance in this relationship. All individuals born in Stockholm County 1987-1991 (n = 107,287) constituted our cohort. Seven CAs were measured between birth and age 14: familial death, parental criminality, parental substance abuse and psychiatric morbidity, parental separation and/or single-parent household, household public assistance and residential instability. Individuals were followed from their 18th birthday until they were diagnosed with PD or until end of follow-up (December 31st 2011). Adjusted estimates of risk of PD were calculated as hazard ratios (HR) with 95% confidence intervals (CI). Associations were observed between cumulative CA and PD. During the follow-up 770 individuals (0.7%) were diagnosed with PD. Individuals exposed to 3+ CAs had the highest risks of being diagnosed with PD (HR 3.0, 95% CI 2.4-3.7). Childhood psychopathology and low school grades further increased the risk of PD among individuals exposed to CA. Cumulative CA is strongly associated with a diagnosis of PD in young adulthood. Our findings indicate that special attention should be given in schools and health services to children exposed to adversities to prevent decline in school performance, and to detect vulnerable individuals that may be on negative life-course trajectories.

Ort, förlag, år, upplaga, sidor
SPRINGER , 2017. Vol. 32, nr 8, s. 721-731
Nyckelord [en]
Childhood adversity, Personality disorder, Epidemiology, Cohort, Sweden
Nationell ämneskategori
Medicin och hälsovetenskap
Identifikatorer
URN: urn:nbn:se:uu:diva-335716DOI: 10.1007/s10654-017-0264-9ISI: 000410179400009PubMedID: 28560537OAI: oai:DiVA.org:uu-335716DiVA, id: diva2:1164252
Forskningsfinansiär
Forte, Forskningsrådet för hälsa, arbetsliv och välfärdTillgänglig från: 2017-12-11 Skapad: 2017-12-11 Senast uppdaterad: 2017-12-11Bibliografiskt granskad

Open Access i DiVA

fulltext(437 kB)68 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 437 kBChecksumma SHA-512
5207bd4ca57b33c87f708f4721f8739eac555f3830c550143af27fb256df0c659dcb7f47f61d94e10ed0a9c1233faa52446ab59c80c49f3f924cc2fe09c79d32
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Ekselius, Lisa

Sök vidare i DiVA

Av författaren/redaktören
Ekselius, Lisa
Av organisationen
Psykiatri, Akademiska sjukhuset
I samma tidskrift
European Journal of Epidemiology
Medicin och hälsovetenskap

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 68 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 115 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf