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Fracture strength of glass chips for high-pressure microfluidics
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology.ORCID iD: 0000-0002-3966-0220
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology.ORCID iD: 0000-0003-2744-1634
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology.
2016 (English)In: Journal of Micromechanics and Microengineering, ISSN 0960-1317, E-ISSN 1361-6439, Vol. 26, no 9, article id 095009Article in journal (Refereed) Published
Abstract [en]

High-pressure microfluidics exposes new areas in chemistry. In this paper, the reliability of transparent borosilicate glass chips is investigated. Two designs of circular cavities are used for fracture strength tests, either 1.6 mm wide with rounded corners to the fluid inlets, or 2.0 mm wide with sharp inlet corners. Two kinds of tests are done, either short-term,e.g. pressurization to fracture at room temperature, or long-term, with fracture at constant pressurization for up to one week, in the temperature region 11–125 °C. The speed of crack fronts is measured using a high-speed camera. Results show fracture stresses in the range of 129 and 254 MPa for short-term measurements. Long-term measurements conclude the presences of a temperature and stress dependent delayed fracture. For a reliability ofone week at 11–38 °C, a pressure limit is found at the lower end of the short-term measurements, or 15% lower than the average. At 80 °C, this pressure limit is 45% lower. Crack speeds are measured to be 10−5 m s-1 during short-term fracture. These measurements are comparable with estimations based on slow crack growth and show that the growth affects the reliability of glass chips. This effect is strongly affected by high temperatures, thus lowers the operating window of high-pressure glass microfluidic devices.

Place, publisher, year, edition, pages
2016. Vol. 26, no 9, article id 095009
Keywords [en]
glass, fracture strength, high pressure microfluidics, crack growth, temperature dependence
National Category
Other Engineering and Technologies not elsewhere specified
Research subject
Engineering Science with specialization in Microsystems Technology
Identifiers
URN: urn:nbn:se:uu:diva-309983DOI: 10.1088/0960-1317/26/9/095009ISI: 000402408400009OAI: oai:DiVA.org:uu-309983DiVA, id: diva2:1054638
Funder
Swedish Research Council, 2011:5037Knut and Alice Wallenberg FoundationAvailable from: 2016-12-08 Created: 2016-12-08 Last updated: 2018-06-19Bibliographically approved
In thesis
1. Microfluidics at High Pressures: Understanding, Sensing, and Control
Open this publication in new window or tab >>Microfluidics at High Pressures: Understanding, Sensing, and Control
2018 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

This thesis explores understanding, sensing, and control in high-pressure microfluidics. The high-pressure regime allows fluids to be forced through narrow channels at substantial speed and creates conditions for fluids of high density and low viscosity—features desired in flow-based chemical analyses. With changes to pressure and temperature, fluid properties vary, and for miniaturized flow systems, sensing and control are needed.

For miniaturized chemical analytics to utilize high-pressure fluids, like supercritical CO2, sensors are required for flow characterization. In this thesis, high-pressure tolerant sensors in glass chips have been developed and investigated. By the use of chip-integrated temperature, flow, and relative permittivity sensors, the variable behavior of supercritical CO2 or binary component CO2-alcohol mixtures have been investigated. To be able to change flow rates, a heat-based actuator chip has been developed. By a flow control system, which combines a relative permittivity sensor and heat actuated flow regulators on a modular system, the composition of binary component CO2-alcohol mixtures can be tuned and controlled with feedback.

Flows of multiphase CO2-H2O hold promise for miniaturized extraction systems. In this thesis, parallel multiphase CO2-H2O flow has been studied. To achieve control, methods have been investigated where channels have been modified by the introduction of a guiding ridge and altered by a chemical coating. Flow is a dynamic process, where pressure and temperature can vary with time and place. As the properties of fluids containing CO2 may change with pressure and temperature, properties will also change with time and place. Because of this, instruments with spatial and temporal resolution are needed to better understand dynamic chemical effects at flow. In this thesis, a tool is presented to study the dynamic acidification of aqueous solutions that come in contact with flowing CO2.

By a study performed to understand the strength and pressure tolerance of glass chips, it has been found that the fracture is not only determined by the applied pressure, but also on time and environment.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2018. p. 60
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1651-6214 ; 1687
Keywords
High-pressure microfluidics, supercritical CO2, compressible flow, relative permittivity, integrated electrodes
National Category
Chemical Engineering Materials Engineering
Research subject
Engineering Science with specialization in Microsystems Technology
Identifiers
urn:nbn:se:uu:diva-353964 (URN)978-91-513-0372-7 (ISBN)
Public defence
2018-09-14, Polhemsalen, Ångströmlaboratoriet, Lägerhyddsvägen 1, Uppsala, 13:00 (English)
Opponent
Supervisors
Available from: 2018-08-21 Created: 2018-06-19 Last updated: 2018-08-27

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Andersson, MartinHjort, KlasKlintberg, Lena

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