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Algorithm to Diagnose Delayed and Late PJI: Role of Joint Aspiration
CHU Vaudois, Dept Musculoskeletal Syst, Orthopaed Trauma Unit, Dept Sept Surg, Lausanne, Switzerland.
Hosp Valle De Hebron, Dept Orthopaed Surg, Reconstruct & Sept Surg Unit, Barcelona, Spain.
Helios ENDO Klin, Hamburg, Germany.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics.
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2017 (English)In: A Modern Approach to Biofilm-Related Orthopaedic Implant Infections: Advances in Microbiology, Infectious Diseases and Public Health Volume 5 / [ed] Drago, Lorenzo, Cham, Switzerland: Springer, 2017, p. 101-111Chapter in book (Refereed)
Abstract [en]

Total Joint Arthroplasty (TJA) continues to gain acceptance as the standard of care for the treatment of severe degenerative joint disease, and is considered one of the most successful surgical interventions in the history of medicine. A devastating complication after TJA is infection. Periprosthetic joint infection (PJI), represents one of the major causes of failure and remains a significant challenge facing orthopaedics today. PJI usually requires additional surgery including revision of the implants, fusion or amputations causing tremendous patient suffering but also a heavy health economics burden. PJI is at the origin of around 20–25 % of total knee arthroplasty (Bozic et al. 2010; de Gorter et al. 2015; Sundberg et al. 2015) and 12–15 % of total hip arthroplasty (Bozic et al. 2009; Garellick et al. 2014; de Gorter et al. 2015) failures.

Place, publisher, year, edition, pages
Cham, Switzerland: Springer, 2017. p. 101-111
Series
Advances in Experimental Medicine and Biology, ISSN 0065-2598, E-ISSN 2214-8019 ; 971
Keywords [en]
Total Joint Arthroplasty (TJA), Infection, Diagnosties, Algorithm, Joint aspiration, Alpha-defensin
National Category
Orthopaedics
Identifiers
URN: urn:nbn:se:uu:diva-316523DOI: 10.1007/5584_2016_153ISI: 000446017300008PubMedID: 27757937ISBN: 978-3-319-52273-9 (print)ISBN: 978-3-319-52274-6 (electronic)OAI: oai:DiVA.org:uu-316523DiVA, id: diva2:1078017
Available from: 2017-03-02 Created: 2017-03-02 Last updated: 2018-12-10Bibliographically approved

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