uu.seUppsala universitets publikasjoner
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Association between childhood adversity and a diagnosis of personality disorder in young adulthood: a cohort study of 107,287 individuals in Stockholm County
Karolinska Inst, Div Social Med, Dept Publ Hlth Sci, Stockholm, Sweden.;Univ Calif Los Angeles, Fielding Sch Publ Hlth, Calif Ctr Populat Res, Dept Community Hlth Sci, Los Angeles, CA 90095 USA..
Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Psykiatri, Akademiska sjukhuset.
Karolinska Inst, Div Social Med, Dept Publ Hlth Sci, Stockholm, Sweden..
Karolinska Inst, Div Publ Hlth Epidemiol, Dept Publ Hlth Sci, Stockholm, Sweden.;Stockholm Cty Council, Ctr Epidemiol & Community Med, Stockholm, Sweden..
Vise andre og tillknytning
2017 (engelsk)Inngår i: European Journal of Epidemiology, ISSN 0393-2990, E-ISSN 1573-7284, Vol. 32, nr 8, s. 721-731Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Childhood adversity (CA) may increase the risk for later developing of personality disorder (PD). However, less is known about the association between cumulative CA and PD, and the role of childhood psychopathology and school performance. The current study examined the relationship between a range of CAs and a diagnosis of PD in young adulthood, and the roles of childhood psychopathology and school performance in this relationship. All individuals born in Stockholm County 1987-1991 (n = 107,287) constituted our cohort. Seven CAs were measured between birth and age 14: familial death, parental criminality, parental substance abuse and psychiatric morbidity, parental separation and/or single-parent household, household public assistance and residential instability. Individuals were followed from their 18th birthday until they were diagnosed with PD or until end of follow-up (December 31st 2011). Adjusted estimates of risk of PD were calculated as hazard ratios (HR) with 95% confidence intervals (CI). Associations were observed between cumulative CA and PD. During the follow-up 770 individuals (0.7%) were diagnosed with PD. Individuals exposed to 3+ CAs had the highest risks of being diagnosed with PD (HR 3.0, 95% CI 2.4-3.7). Childhood psychopathology and low school grades further increased the risk of PD among individuals exposed to CA. Cumulative CA is strongly associated with a diagnosis of PD in young adulthood. Our findings indicate that special attention should be given in schools and health services to children exposed to adversities to prevent decline in school performance, and to detect vulnerable individuals that may be on negative life-course trajectories.

sted, utgiver, år, opplag, sider
SPRINGER , 2017. Vol. 32, nr 8, s. 721-731
Emneord [en]
Childhood adversity, Personality disorder, Epidemiology, Cohort, Sweden
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-335716DOI: 10.1007/s10654-017-0264-9ISI: 000410179400009PubMedID: 28560537OAI: oai:DiVA.org:uu-335716DiVA, id: diva2:1164252
Forskningsfinansiär
Forte, Swedish Research Council for Health, Working Life and WelfareTilgjengelig fra: 2017-12-11 Laget: 2017-12-11 Sist oppdatert: 2017-12-11bibliografisk kontrollert

Open Access i DiVA

fulltext(437 kB)68 nedlastinger
Filinformasjon
Fil FULLTEXT01.pdfFilstørrelse 437 kBChecksum SHA-512
5207bd4ca57b33c87f708f4721f8739eac555f3830c550143af27fb256df0c659dcb7f47f61d94e10ed0a9c1233faa52446ab59c80c49f3f924cc2fe09c79d32
Type fulltextMimetype application/pdf

Andre lenker

Forlagets fulltekstPubMed

Personposter BETA

Ekselius, Lisa

Søk i DiVA

Av forfatter/redaktør
Ekselius, Lisa
Av organisasjonen
I samme tidsskrift
European Journal of Epidemiology

Søk utenfor DiVA

GoogleGoogle Scholar
Totalt: 68 nedlastinger
Antall nedlastinger er summen av alle nedlastinger av alle fulltekster. Det kan for eksempel være tidligere versjoner som er ikke lenger tilgjengelige

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 115 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf