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Bone Cement Embedded in a Microfluidic Device
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology. (EMBLA)ORCID iD: 0000-0002-5645-8323
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology. (EMBLA)
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Materials Sciences. (MiM)ORCID iD: 0000-0001-7004-2853
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Microsystems Technology. (EMBLA)ORCID iD: 0000-0002-1264-1337
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2018 (English)Conference paper, Poster (with or without abstract) (Refereed)
Abstract [en]

Calcium phosphate cements (CPCs) have a great potential in the treatment of bone disorders due to their excellent biocompatibility. Although CPCs are promising when implanted in vivo, there is poor correlation between in vitro and in vivo studies. This could be because most conventional in vitro systems lack a 3D architecture, or dynamic conditions (i.e. a continuous refreshment stream). The aim of this work is to embed CPCs into a microfluidic system and evaluate ion and protein exchange at different flow rates.

Place, publisher, year, edition, pages
2018.
Keywords [en]
Calcium Phosphate Cements, Microfluidic Chip, Continuous flow, Biomaterial Evaluation, Bone implants, Cells
National Category
Other Materials Engineering Engineering and Technology
Research subject
Engineering Science with specialization in Microsystems Technology
Identifiers
URN: urn:nbn:se:uu:diva-363447OAI: oai:DiVA.org:uu-363447DiVA, id: diva2:1257079
Conference
Micronano System Workshop (MSW), May 13-15, 2018, Aalto University, Espoo, Finland
Funder
Swedish Research Council Formas, 2016-00781Knut and Alice Wallenberg Foundation, WAF 2016-0112Swedish Research Council, 2017-05051Available from: 2018-10-18 Created: 2018-10-18 Last updated: 2018-12-04Bibliographically approved

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Atif, Abdul RaoufCarter, Sarah-SophiaPujari-Palmer, MichaelTenje, MariaMestres, Gemma

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