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Scandinavian Multicenter Acute Subdural Hematoma (SMASH) Study: Study Protocol for a Multinational Population-Based Consecutive Cohort
Copenhagen Univ Hosp, Dept Neurosurg, Rigshosp, Copenhagen, Denmark;Karolinska Univ Hosp, Dept Neurosurg, Karolinskavagen, Stockholm, Sweden.
Copenhagen Univ Hosp, Dept Neurosurg, Rigshosp, Copenhagen, Denmark.
Karolinska Univ Hosp, Dept Neurosurg, Karolinskavagen, Stockholm, Sweden.
Odense Univ Hosp, Dept Neurosurg, Odense, Denmark.ORCID-id: 0000-0002-0325-0262
Vise andre og tillknytning
2019 (engelsk)Inngår i: Neurosurgery, ISSN 0148-396X, E-ISSN 1524-4040, Vol. 84, nr 3, s. 799-803Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

BACKGROUND

Traumatic acute subdural hematomas (ASDHs) are associated with high rate of morbidity and mortality, especially in elderly individuals. However, recent reports indicate that the morbidity and mortality rates might have improved.

OBJECTIVE

To evaluate postoperative (30-d) mortality in younger vs elderly (70 yr) patients with ASDH. Comparing younger and elderly patients, the secondary objectives are morbidity patterns of care and 6 mo outcome according to Glasgow outcome scale (GOS). Finally, in patients with traumatic ASDH, we aim to provide prognostic variables.

METHODS

This is a large-scale population-based Scandinavian study including all neurosurgical departments in Denmark and Sweden. All adult (18 yr) patients surgically treated between 2010 and 2014 for a traumatic ASDH in Denmark and Sweden will be included. Identification at clinicaltrials.gov is NCT03284190.

EXPECTED OUTCOMES

We expect to provide data on potential differences between younger vs elderly patients in terms of mortality and morbidity. We hypothesize that elderly patients selected for surgery have a similar pattern of care as compared with younger patients. We will provide functional outcome in terms of GOS at 6 mo in younger vs elderly patients undergoing ASDH evacuation. Finally, clinical useful prognostic factors for favorable (GOS 4-5) vs unfavorable (GOS 1-3) will be identified.

DISCUSSION

An improved understanding of the clinical outcome, treatment and resource allocation, clinical course, and the prognostic factors of traumatic ASDH will allow neurosurgeons to make better treatment decisions.

sted, utgiver, år, opplag, sider
2019. Vol. 84, nr 3, s. 799-803
Emneord [en]
Acute subdural hematoma, Outcome, Elderly, Predictors
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-379927DOI: 10.1093/neuros/nyy173ISI: 000460636600076PubMedID: 29762769OAI: oai:DiVA.org:uu-379927DiVA, id: diva2:1299601
Tilgjengelig fra: 2019-03-27 Laget: 2019-03-27 Sist oppdatert: 2019-03-27bibliografisk kontrollert

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