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Weinreb Amides as Directing Groups for Transition Metal-Catalyzed C-H Functionalizations
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - BMC, Organic Chemistry.
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - BMC, Organic Chemistry.ORCID iD: 0000-0002-9353-2238
2019 (English)In: Molecules, ISSN 1420-3049, E-ISSN 1420-3049, Vol. 24, no 5, article id 830Article, review/survey (Refereed) Published
Abstract [en]

Weinreb amides are a privileged, multi-functional group with well-established utility in classical synthesis. Recently, several studies have demonstrated the use of Weinreb amides as interesting substrates in transition metal-catalyzed C-H functionalization reactions. Herein, we review this part of the literature, including the metal catalysts, transformations explored so far and specific insights from mechanistic studies.

Place, publisher, year, edition, pages
MDPI , 2019. Vol. 24, no 5, article id 830
Keywords [en]
C-H functionalization, directing groups, amides, transition metals, catalysis
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:uu:diva-382776DOI: 10.3390/molecules24050830ISI: 000462662900006PubMedID: 30813564OAI: oai:DiVA.org:uu-382776DiVA, id: diva2:1313177
Funder
Wenner-Gren FoundationsAvailable from: 2019-05-02 Created: 2019-05-02 Last updated: 2019-05-02Bibliographically approved

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Kalepu, JagadeeshPilarski, Lukasz T.

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