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Validation of the Swedish Multidimensional Dyspnea Profile (MDP) in outpatients with cardiorespiratory disease
Lund Univ, Fac Med, Resp Med & Allergol, Dept Clin Sci, Lund, Sweden;Blekinge Hosp, Dept Med, Karlskrona, Sweden.
Hans Bornefalk AB, Vallentuna, Sweden.
Karolinska Inst, Dept Med Solna, Resp Med Unit, Stockholm, Sweden;Karolinska Inst, Ctr Mol Med, Stockholm, Sweden.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.ORCID iD: 0000-0001-5093-6980
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2019 (English)In: BMJ OPEN RESPIRATORY RESEARCH, ISSN 2052-4439, Vol. 6, no 1, article id UNSP e000381Article in journal (Refereed) Published
Abstract [en]

Introduction Breathlessness is a cardinal symptom in cardiorespiratory disease. An instrument for measuring different aspects of breathlessness was recently developed, the Multidimensional Dyspnea Profile (MDP). This study aimed to validate the MDP in terms of the underlying factor structure, internal consistency, test-retest reliability and concurrent validity in Swedish outpatients with cardiorespiratory disease. Methods Outpatients with stable cardiorespiratory disease and breathlessness in daily life were recruited. Factor structure of MDP was analysed using confirmatory factor analysis; internal consistency was analysed using Cronbach's alpha; and test-retest reliability was analysed using intraclass correlation coefficients (ICCs) for patients with unchanged breathlessness between assessments (baseline, after 30-90 min and 2 weeks). Concurrent validity was evaluated using correlations with validated scales of breathlessness, anxiety, depression and health-related quality of life. Results In total, 182 outpatients with cardiorespiratory disease and breathlessness in daily life were included; 53.3% were women; main diagnoses were chronic obstructive pulmonary disease (24.7%), asthma (21.4%), heart failure (19.2%) and idiopathic pulmonary fibrosis (18.7%). The MDP total, immediate perception and emotional response scores, and individual item scores showed expected factor structure and acceptable measurement properties: internal consistency (Cronbach's alpha, range 0.80-0.93); test-retest reliability at 30-90 min and 2 weeks (ICC, range 0.67-0.91); and concurrent validity. There was no evidence of a learning effect. Findings were similar between diagnoses. Discussion MDP is a valid instrument for multidimensional measurement of breathlessness in Swedish outpatients across cardiorespiratory diseases.

Place, publisher, year, edition, pages
BMJ PUBLISHING GROUP , 2019. Vol. 6, no 1, article id UNSP e000381
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Respiratory Medicine and Allergy
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URN: urn:nbn:se:uu:diva-400011DOI: 10.1136/bmjresp-2018-000381ISI: 000500491400001PubMedID: 31681476OAI: oai:DiVA.org:uu-400011DiVA, id: diva2:1380988
Funder
Swedish Heart Lung FoundationAvailable from: 2019-12-19 Created: 2019-12-19 Last updated: 2019-12-19Bibliographically approved

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Jansson, ChristerBornefalk Hermansson, AnnaIgelström, Helena

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