Logo: to the web site of Uppsala University

uu.sePublications from Uppsala University
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Nutrient Intake and Its Association with Appendicular Total Lean Mass and Muscle Function and Strength in Older Adults: A Population-Based Study
Stavanger Univ Hosp, Ctr Age Related Med SESAM, N-4011 Stavanger, Norway.;Pontificia Univ Javeriana, Ageing Inst, Med Sch, Semillero Neurociencias & Envejecimiento, Bogota 110231, Colombia.;Karolinska Inst, Div Clin Geriatr, Ctr Alzheimer Res, Dept Neurobiol Care Sci & Soc, S-14186 Stockholm, Sweden..ORCID iD: 0000-0001-5832-0603
Univ Gothenburg, Inst Neurosci & Physiol, Sahlgrenska Acad, S-41345 Gothenburg, Sweden..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism. Karolinska Univ Hosp, Theme Inflammat & Aging, S-14186 Stockholm, Sweden..ORCID iD: 0000-0003-3705-0725
Stavanger Univ Hosp, Ctr Age Related Med SESAM, N-4011 Stavanger, Norway.;Univ Autonoma Santo Domingo, Escuela Estadist, Santo Domingo 10103, Dominican Rep..
Show others and affiliations
2024 (English)In: Nutrients, E-ISSN 2072-6643, Vol. 16, no 4, article id 568Article in journal (Refereed) Published
Abstract [en]

Treatment options for sarcopenia are currently limited, and primarily rely on two main therapeutic approaches: resistance-based physical activity and dietary interventions. However, details about specific nutrients in the diet or supplementation are unclear. We aim to investigate the relationship between nutrient intake and lean mass, function, and strength. Data were derived from the Gothenburg H70 birth cohort study in Sweden, including 719,70-year-olds born in 1944 (54.1% females). For independent variables, the diet history method (face-to-face interviews) was used to estimate habitual food intake during the preceding three months. Dependent variables were gait speed (muscle performance), hand grip strength (muscle strength), and the appendicular lean soft tissue index (ALSTI). Linear regression analyses were performed to analyze the relationship between the dependent variables and each of the covariates. Several nutrients were positively associated with ALSTI, such as polyunsaturated fatty acids (DHA, EPA), selenium, zinc, riboflavin, niacin equivalent, vitamin B12, vitamin D, iron, and protein. After correction for multiple comparisons, there were no remaining correlations with handgrip and gait speed. Findings of positive correlations for some nutrients with lean mass suggest a role for these nutrients in maintaining muscle volume. These results can be used to inform clinical trials to expand the preventive strategies and treatment options for individuals at risk of muscle loss and sarcopenia.

Place, publisher, year, edition, pages
MDPI, 2024. Vol. 16, no 4, article id 568
Keywords [en]
sarcopenia, body composition, aging, diet, walking speed, muscle strength
National Category
Geriatrics Nutrition and Dietetics
Identifiers
URN: urn:nbn:se:uu:diva-525076DOI: 10.3390/nu16040568ISI: 001172347500001PubMedID: 38398892OAI: oai:DiVA.org:uu-525076DiVA, id: diva2:1845625
Available from: 2024-03-19 Created: 2024-03-19 Last updated: 2024-03-19Bibliographically approved

Open Access in DiVA

fulltext(576 kB)67 downloads
File information
File name FULLTEXT01.pdfFile size 576 kBChecksum SHA-512
9a8b1e23a38e1d961cd1d036c7eac64c83a97571690cb044fbcb0a04f5570c166ff6661d294be9398ee2334805a245f78c11bac43dec773afc3d9473cc532c1e
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records

Cederholm, Tommy

Search in DiVA

By author/editor
Borda, Miguel GermanCederholm, TommyPerez-Zepeda, Mario UlisesRyden, LinaGonzalez-Lara, MarianaSalazar-Londono, SalomonDuque, Gustavo
By organisation
Clinical Nutrition and Metabolism
In the same journal
Nutrients
GeriatricsNutrition and Dietetics

Search outside of DiVA

GoogleGoogle Scholar
Total: 71 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 118 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf