Is there evidence for convergent evolution around human microsatellites?
2007 (English)In: Molecular biology and evolution, ISSN 0737-4038, E-ISSN 1537-1719, Vol. 24, no 5, p. 1097-1100Article in journal (Refereed) Published
Abstract [en]
A study by Vowles and Amos (2004) identified atypical patterns of base composition around human microsatellites and argued that microsatellites generate mutational biases in their flanking regions. Here, we perform simulations of molecular evolution using a simple model that suggest similar patterns can be produced without any such biases in genome evolution.
Place, publisher, year, edition, pages
2007. Vol. 24, no 5, p. 1097-1100
Keywords [en]
Convergent evolution, Genome evolution, Microsatellite, Mutation bias, Simulation
National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:uu:diva-15693DOI: 10.1093/molbev/msm051ISI: 000246802400002PubMedID: 17350937OAI: oai:DiVA.org:uu-15693DiVA, id: diva2:43464
2008-03-032008-03-032017-12-08