Incomplete inversion of the hippocampus: a common developmental anomalyShow others and affiliations
2008 (English)In: European Radiology, ISSN 0938-7994, E-ISSN 1432-1084, Vol. 18, no 1, p. 138-142Article in journal (Refereed) Published
Abstract [en]
Incomplete inversion of the hippocampus, an imperfect fetal development, has been described in patients with epilepsy or severe midline malformations. We studied this condition in a nonepileptic population without obvious developmental anomalies. We analyzed the coronal MR images of 50 women and 50 men who did not have epilepsy. Twenty of them were healthy volunteers and 80 were patients without obvious intracranial developmental anomalies, intracranial masses, hydrocephalus or any condition affecting the temporal lobes. If the entire hippocampus (the head could not be evaluated) were affected, the incomplete inversion was classified as total, otherwise as partial. Incomplete inversion of the hippocampus was found in 19/100 subjects (9 women, 10 men). It was unilateral, always on the left side, in 13 subjects (4 women, 9 men): 9 were of the total type, 4 were partial. It was bilateral in six subjects (five women, one man): four subjects had total types bilaterally, two had a combination of total and partial types. The collateral sulcus was vertically oriented in all subjects with a deviating hippocampal shape. We conclude that incomplete inversion of the hippocampus is not an unusual morphologic variety in a nonepileptic population without other obvious intracranial developmental anomalies.
Place, publisher, year, edition, pages
2008. Vol. 18, no 1, p. 138-142
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-15863DOI: 10.1007/s00330-007-0735-6ISI: 000252593500016PubMedID: 17828540OAI: oai:DiVA.org:uu-15863DiVA, id: diva2:43634
2008-06-182008-06-182017-12-08Bibliographically approved