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Acquired hemophagocytic lymphohistiocytosis associated with multiple myeloma
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2011 (Engelska)Ingår i: Medical Oncology, ISSN 1357-0560, E-ISSN 1559-131X, Vol. 28, nr 2, s. 539-543Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Acquired or secondary hemophagocytic lymphohistiocytosis (sHLH) is a life-threatening hyperinflammation syndrome caused mostly by various infectious agents, autoimmune disorders or malignancy. So far, only anecdotal cases of sHLH associated with multiple myeloma have been published. We provide a review of all these reports and include a previously not published case of myeloma-associated sHLH in a 59-year-old male with complex partial epilepsy. Due to aggressive course of sHLH, increased awareness is indicated in all patients with malignancies which develop unremitting fever, cytopenia and splenomegaly. Early diagnosis and immediate introduction of adequate therapy is crucial for the outcome of HLH.

Ort, förlag, år, upplaga, sidor
2011. Vol. 28, nr 2, s. 539-543
Nationell ämneskategori
Klinisk medicin
Identifikatorer
URN: urn:nbn:se:uu:diva-233806DOI: 10.1007/s12032-010-9484-5PubMedID: 20358309OAI: oai:DiVA.org:uu-233806DiVA, id: diva2:754354
Tillgänglig från: 2014-10-10 Skapad: 2014-10-10 Senast uppdaterad: 2017-12-05Bibliografiskt granskad

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