uu.seUppsala universitets publikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Fruit and vegetable intake and risk of hip fracture: A cohort study of Swedish men and women
Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper, Ortopedi.ORCID-id: 0000-0002-4421-6466
Karolinska Inst, Unit Nutr Epidemiol, Inst Environm Med, Solna, Sweden.
Karolinska Inst, Unit Nutr Epidemiol, Inst Environm Med, Solna, Sweden.
Karolinska Inst, Unit Nutr Epidemiol, Inst Environm Med, Solna, Sweden.
Visa övriga samt affilieringar
2015 (Engelska)Ingår i: Journal of Bone and Mineral Research, ISSN 0884-0431, E-ISSN 1523-4681, Vol. 30, nr 6, s. 976-984Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Dietary guidelines recommend a daily intake of five servings of fruit and vegetables. Whether such intakes are associated with a lower risk of hip fracture is at present unclear. The aim of the present study was to investigate the dose-response association between habitual fruit and vegetable intake and hip fracture in a cohort study based on 40,644 men from the Cohort of Swedish Men (COSM) and 34,947 women from the Swedish Mammography Cohort (SMC) (total n=75,591), free from cardiovascular disease and cancer, who answered lifestyle questionnaires in 1997 (age 45-83 years). Intake of fruit and vegetables (servings/day) was assessed by food frequency questionnaire and incident hip fractures were retrieved from the Swedish Patient Register (1998-2010). The mean follow-up time was 14.2 years. One third of the participants reported an intake of fruit and vegetables of >5 servings/day, one third >3 to ≤5 servings/day, 28% >1 to ≤3 servings/day, and 6% reported ≤1 serving/day. During 1,037,645 person-years we observed 3,644 hip fractures (2,266, 62%, in women). The doseresponse association was found to be strongly non-linear (P<0.001). Men and women with zero consumption had 88% higher rate of hip fracture compared with those consuming 5 servings/day; adjusted hazard ratio (HR), 1.88 (95% CI, 1.53-2.32). The rate was gradually lower with higher intakes; adjusted HR for 1 vs 5 servings/day, 1.35 (95% CI, 1.21-1.58). However, more than 5 servings/day did not confer additionally lower HRs (adjusted HR for 8 vs. 5 servings/day, 0.96 (95% CI, 0.90-1.03). Similar results were observed when men and women were analyzed separately. We conclude that there is a dose-response association between fruit and vegetable intake and hip fracture such that an intake below the recommended 5 servings/day confers higher rates of hip fracture. Intakes above this recommendation do not seem to further lower the risk.

Ort, förlag, år, upplaga, sidor
2015. Vol. 30, nr 6, s. 976-984
Nationell ämneskategori
Ortopedi
Identifikatorer
URN: urn:nbn:se:uu:diva-242716DOI: 10.1002/jbmr.2384ISI: 000354624500005PubMedID: 25294687OAI: oai:DiVA.org:uu-242716DiVA, id: diva2:785451
Forskningsfinansiär
VetenskapsrådetTillgänglig från: 2015-02-03 Skapad: 2015-01-30 Senast uppdaterad: 2018-08-24Bibliografiskt granskad

Open Access i DiVA

fulltext(308 kB)183 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 308 kBChecksumma SHA-512
5e345eb1d338a305a3b018eb1b7395ec008191e7ead9b4314f999e047a4d3e76e8cc33b5fac9c121d21319b6cad0a8de6e747ae08e50874b1d3f798bcf285125
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Byberg, LiisaMichaëlsson, Karl

Sök vidare i DiVA

Av författaren/redaktören
Byberg, LiisaMichaëlsson, Karl
Av organisationen
Ortopedi
I samma tidskrift
Journal of Bone and Mineral Research
Ortopedi

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 183 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 637 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf