uu.seUppsala universitets publikasjoner
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Impact of obstetric factors on outcome of extremely preterm births in Sweden: prospective population-based observational study (EXPRESS)
Lund Univ, Ctr Reprod Epidemiol, Lund, Sweden..
Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Pediatrik. Umea Univ, Dept Clin Sci Pediat, Umea, Sweden.. (Perinatal, neonatal och barnkardiologisk forskning)
Karolinska Univ Hosp Huddinge, Dept Obstet & Gynecol, Stockholm, Sweden..
Lund Univ, Dept Obstet & Gynecol, Clin Sci Lund, Lund, Sweden..
Vise andre og tillknytning
2015 (engelsk)Inngår i: Acta Obstetricia et Gynecologica Scandinavica, ISSN 0001-6349, E-ISSN 1600-0412, Vol. 94, nr 11, s. 1203-1214Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

IntroductionA population-based observational study investigated the contribution of obstetric factors to the survival and postnatal development of extremely preterm infants. Material and methodsMortality up to 1year and neurodevelopment at 2.5years (Bayley-III test, cerebral palsy, vision, hearing) were evaluated in infants born before 27weeks of gestation in Sweden 2004-2007 (n=1011), using logistic regression analyses of risk factors. ResultsOf 844 fetuses alive at admission, 8.4% died in utero before labor, 7.8% died intrapartum. Of 707 live-born infants, 15% died within 24h, 70% survived 365days, 64% were assessed at 2.5years. The risk of death within 24h after birth decreased with gestational age [odds ratio (OR) 0.3; 95% CI 0.2-0.4], antenatal corticosteroids (OR 0.3; 95% CI 0.1-0.6), and cesarean section (OR 0.4; 95% CI 0.2-0.9); it increased with multiple birth (OR 3.0; 95% CI 1.5-6.0), vaginal breech delivery (OR 2.3; 95% CI 1.0-5.1), 5-min Apgar score <4 (OR 50.4; 95% CI 28.2-90.2), and birth at a level II hospital (OR 2.6; 95% CI 1.2-5.3). The risk of death between 1 and 365days remained significantly decreased for gestational age and corticosteroids. The risk of mental developmental delay at 2.5 years decreased with gestational age, birthweight and fetal growth; it increased with vaginal breech delivery (OR 2.0; 95% CI 1.2-7.4), male gender, low Apgar score and high Clinical Risk Index for Babies score. ConclusionSeveral obstetric factors, including abdominal delivery, influenced the risk of death within the first day of life, but not later. Antenatal corticosteroids and gestational age decreased the mortality up to 1year. Mental developmental delay was related to vaginal breech delivery.

sted, utgiver, år, opplag, sider
2015. Vol. 94, nr 11, s. 1203-1214
Emneord [en]
Extremely preterm birth, mortality, risk factors, obstetric interventions, neurodevelopmental outcome, cesarean section, breech delivery
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-266682DOI: 10.1111/aogs.12726ISI: 000362844400009PubMedID: 26249263OAI: oai:DiVA.org:uu-266682DiVA, id: diva2:868928
Forskningsfinansiär
Swedish Research Council, 2006-3855, 2009-4250
Merknad

Co-author: Bo Strömberg, Uppsala universitet, Institutionen för kvinnors och barns hälsa, pediatrik, forskargrupp Barnneurologisk forskning ingår i EXPRESS-gruppen.

Tilgjengelig fra: 2015-11-12 Laget: 2015-11-10 Sist oppdatert: 2017-12-07bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekstPubMed

Personposter BETA

Serenius, FredrikStrömberg, Bo

Søk i DiVA

Av forfatter/redaktør
Serenius, FredrikStrömberg, Bo
Av organisasjonen
I samme tidsskrift
Acta Obstetricia et Gynecologica Scandinavica

Søk utenfor DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 630 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf