uu.seUppsala universitets publikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Rapid evolution of the intersexual genetic correlation for fitness in Drosophila melanogaster
UCL, Res Dept Genet Evolut & Environm, London, England.;Univ Queensland, Sch Biol Sci, St Lucia, Qld, Australia..
UCL, Res Dept Genet Evolut & Environm, London, England..
UCL, Res Dept Genet Evolut & Environm, London, England..
UCL, Res Dept Genet Evolut & Environm, London, England..
Visa övriga samt affilieringar
2016 (Engelska)Ingår i: Evolution, ISSN 0014-3820, E-ISSN 1558-5646, Vol. 70, nr 4, s. 781-795Artikel i tidskrift (Refereegranskat) Published
Resurstyp
Text
Abstract [en]

Sexual antagonism (SA) arises when male and female phenotypes are under opposing selection, yet genetically correlated. Until resolved, antagonism limits evolution toward optimal sex-specific phenotypes. Despite its importance for sex-specific adaptation and existing theory, the dynamics of SA resolution are not well understood empirically. Here, we present data from Drosophila melanogaster, compatible with a resolution of SA. We compared two independent replicates of the LHM population in which SA had previously been described. Both had been maintained under identical, controlled conditions, and separated for around 200 generations. Although heritabilities of male and female fitness were similar, the intersexual genetic correlation differed significantly, being negative in one replicate (indicating SA) but close to zero in the other. Using population sequencing, we show that phenotypic differences were associated with population divergence in allele frequencies at nonrandom loci across the genome. Large frequency changes were more prevalent in the population without SA and were enriched at loci mapping to genes previously shown to have sexually antagonistic relationships between expression and fitness. Our data suggest that rapid evolution toward SA resolution has occurred in one of the populations and open avenues toward studying the genetics of SA and its resolution.

Ort, förlag, år, upplaga, sidor
2016. Vol. 70, nr 4, s. 781-795
Nyckelord [en]
Adaptation, evolutionary genomics, fitness, population genetics, quantitative genetics, sexual conflict
Nationell ämneskategori
Utvecklingsbiologi
Identifikatorer
URN: urn:nbn:se:uu:diva-297380DOI: 10.1111/evo.12892ISI: 000374341100004PubMedID: 27077679OAI: oai:DiVA.org:uu-297380DiVA, id: diva2:941644
Forskningsfinansiär
Vetenskapsrådet, 2004-2572Vetenskapsrådet, 2006-2848Vetenskapsrådet, 2008-5533EU, Europeiska forskningsrådet, 280632Tillgänglig från: 2016-06-22 Skapad: 2016-06-22 Senast uppdaterad: 2017-11-28Bibliografiskt granskad

Open Access i DiVA

fulltext(430 kB)165 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 430 kBChecksumma SHA-512
995021300ae762aea35a77608b9574725034491245b7ad523e57ff9c3bfe6d0113e926770ce4205c240bf2d915640dd899fbb7ad2474569014b25c9ef8b70983
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextPubMed
Av organisationen
Zooekologi
I samma tidskrift
Evolution
Utvecklingsbiologi

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 165 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 367 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf