uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Beta-secretase (BACE) and GSK-3 mRNA levels in Alzheimer's disease
Show others and affiliations
2003 (English)In: Brain Research. Molecular Brain Research, ISSN 0169-328X, E-ISSN 1872-6941, Vol. 116, no 1-2, 155-158 p.Article in journal (Refereed) Published
Abstract [en]

Beta-secretase (BACE) and glycogen synthase kinase (GSK 3) are two enzymes thought to play a role in Alzheimer's disease. We extracted mRNA from 90 Alzheimer and 81 control brains. Levels of mRNA were quantified for BACE and GSK 3 with TaqMan real-time RT-PCR. We found no change in the Alzheimer's disease brains relative to controls for either the BACE or the GSK 3alpha mRNA levels.

Place, publisher, year, edition, pages
2003. Vol. 116, no 1-2, 155-158 p.
Keyword [en]
Alzheimer Disease/*enzymology/genetics/metabolism, Amyloid beta-Protein Precursor/analysis/genetics, Comparative Study, Endopeptidases/genetics/*metabolism, Female, Glial Fibrillary Acidic Protein/analysis/genetics, Glycogen Synthase Kinase 3/genetics/*metabolism, Humans, Male, Microtubule-Associated Proteins/analysis/genetics, Phosphopyruvate Hydratase/analysis/genetics, RNA; Messenger/analysis/biosynthesis, Reverse Transcriptase Polymerase Chain Reaction/methods, Sex Characteristics
National Category
Neurosciences Genetics
Identifiers
URN: urn:nbn:se:uu:diva-72470PubMedID: 12941471OAI: oai:DiVA.org:uu-72470DiVA: diva2:100381
Available from: 2005-05-24 Created: 2005-05-24 Last updated: 2017-12-14Bibliographically approved

Open Access in DiVA

No full text

Other links

PubMedhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=12941471&dopt=Citation

Authority records BETA

Jazin, Elena

Search in DiVA

By author/editor
Jazin, Elena
By organisation
Evolutionary Biology
In the same journal
Brain Research. Molecular Brain Research
NeurosciencesGenetics

Search outside of DiVA

GoogleGoogle Scholar

pubmed
urn-nbn

Altmetric score

pubmed
urn-nbn
Total: 498 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf