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Oxetane modified, conformationally constrained, antisense oligodeoxyribonucleotides function efficiently as gene silencing molecules.
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2004 (English)In: Nucleic Acids Res, ISSN 1362-4962, Vol. 32, no 19, 5791-9 p.Article in journal (Other scientific) Published
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2004. Vol. 32, no 19, 5791-9 p.
Keyword [en]
Cell Division/drug effects, Comparative Study, Ethers; Cyclic/*chemistry, Gene Silencing, Humans, K562 Cells, Nucleic Acid Conformation, Oligodeoxyribonucleotides; Antisense/*chemistry/metabolism/*pharmacology, Proto-Oncogene Proteins c-myb/genetics/metabolism, RNA; Messenger/metabolism, RNA; Small Interfering/*chemistry/metabolism/*pharmacology, Research Support; Non-U.S. Gov't, Research Support; U.S. Gov't; P.H.S., Thionucleotides/chemistry
URN: urn:nbn:se:uu:diva-73468PubMedID: 15514112OAI: oai:DiVA.org:uu-73468DiVA: diva2:101378
Available from: 2005-06-07 Created: 2005-06-07 Last updated: 2011-01-12

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Barman, JChattopadhyaya, J
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Department of Bioorganic Chemistry

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