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Synthesis, physicochemical and biochemical studies of 1',2'-oxetane constrained adenosine and guanosine modified oligonucleotides, and their comparison with those of the corresponding cytidine and thymidine analogues.
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Bioorganic Chemistry.
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2004 (English)In: J Am Chem Soc, ISSN 0002-7863, Vol. 126, no 37, 11484-99 p.Article in journal (Other scientific) Published
Place, publisher, year, edition, pages
2004. Vol. 126, no 37, 11484-99 p.
Keyword [en]
Adenosine/*analogs & derivatives/chemistry, Base Sequence, Circular Dichroism, Cytidine/*analogs & derivatives/chemistry, Deoxyribonuclease I/chemistry/metabolism, Ethers; Cyclic/*chemistry/metabolism, Guanosine/*analogs & derivatives/chemistry, Humans, Kinetics, Models; Molecular, Molecular Sequence Data, Nucleic Acid Conformation, Nucleic Acid Heteroduplexes/chemistry/metabolism, Oligonucleotides/blood/chemical synthesis/*chemistry/metabolism, RNA/chemistry/metabolism, Research Support; Non-U.S. Gov't, Ribonuclease H; Calf Thymus/chemistry/metabolism, Thermodynamics, Thymidine/*analogs & derivatives/chemistry
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URN: urn:nbn:se:uu:diva-73480PubMedID: 15366894OAI: oai:DiVA.org:uu-73480DiVA: diva2:101390
Available from: 2005-06-07 Created: 2005-06-07 Last updated: 2011-01-12

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Cheruku, PradeepPlashkevych, OleksandrChattopadhyaya, Jyoti

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