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Nitric Oxide in the Inner Ear
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences. (Öron-, näs och hals)
2002 (English)In: Current Opinion in Neurology, ISSN 1350-7540, Vol. 15, no 1, 11-15 p.Article in journal (Other (popular science, discussion, etc.)) Published
Abstract [en]

During the past year significant advances have been made in our understanding of the functional significance of nitric oxide (NO) in the inner ear. NO synthase and the NO production site have now been localized using immunohistochemistry and a new fluorescence indicator for NO. The functional significance of NO in the inner ear, in particular as a neurotransmitter, is becoming increasingly clear. Increasing evidence suggests that excessive NO production may play an essential role in inner ear disorders. The production of an inducible form of NO synthase may be closely related to this phenomenon. Based on the mechanisms of inner ear disorders, new pharmacological strategies for preventing or treating inner ear disorders have been suggested.

Place, publisher, year, edition, pages
2002. Vol. 15, no 1, 11-15 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-73588PubMedID: 11796945OAI: oai:DiVA.org:uu-73588DiVA: diva2:101498
Available from: 2005-06-10 Created: 2005-06-10 Last updated: 2010-02-19Bibliographically approved

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