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An investigation into the critical surfactant concentration for solid solubility of hydrophobic drug in different polyethylene glycols
Uppsala University.
Uppsala University.
Uppsala University.
1996 (English)In: INTERNATIONAL JOURNAL OF PHARMACEUTICS, ISSN 0378-5173, Vol. 142, no 2, 189-198 p.Article in journal (Other scientific) Published
Abstract [en]

Solid dispersions of 10% w/w griseofulvin in different polyethylene glycols (PEGs) with or without incorporation of alkali dodecyl sulphates (MDS) were prepared by the melting method. The investigations concerned the solid state (X-ray powder diffraction)

Place, publisher, year, edition, pages
ELSEVIER SCIENCE BV , 1996. Vol. 142, no 2, 189-198 p.
Keyword [en]
crystallinity; solid solution; alkali dodecyl sulphates; griseofulvin; X-ray powder diffraction; ODSC; MTDSC; dielectric spectroscopy; SODIUM DODECYL-SULFATE; PHYSICOCHEMICAL ASPECTS; DISPERSIONS; GRISEOFULVIN; DISSOLUTION; ADDITIONS; RELEASE; SYSTEMS
URN: urn:nbn:se:uu:diva-74263OAI: oai:DiVA.org:uu-74263DiVA: diva2:102173
Addresses: UNIV UPPSALA, CTR BIOMED, DEPT PHYS & INORGAN PHARMACEUT CHEM, S-75123 UPPSALA, SWEDEN. UNIV LONDON, SCH PHARM, CTR MAT SCI, LONDON WC1N 1AX, ENGLAND.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-15

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