Photoinitiaed Free Radical Carbonylation Enhanced by Photosensitizers
2005 (English)In: Organic Letters, Vol. 7, no 21, 4661-4664 p.Article in journal (Refereed) Published
The enchanicing effect of several photsensitizers in photoinitiated radical carbonylation is demonstrated and applied to acceleate the synthesis of compounds labeled with short-lived 11C. With the sensitizers, the synthesis of [carbonyl-11C]esters and acids from alkyl iodides, [11C]carbon monoxides, alcohols, and water provided up to 75-85% decay-corrected radiochemical yields in 6-min reactions under mild conditions. Acetone was used as a sensitier in preparing 13C-substituted 1,10-decanedicarboxylic acid from (13C)carbon monoxide.
Place, publisher, year, edition, pages
2005. Vol. 7, no 21, 4661-4664 p.
IdentifiersURN: urn:nbn:se:uu:diva-74530OAI: oai:DiVA.org:uu-74530DiVA: diva2:102440