Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery
2016 (English)In: Biomaterials Science, ISSN 2047-4830, E-ISSN 2047-4849, Vol. 4, no 9, 1310-1313 p.Article in journal (Refereed) Published
Glycosaminoglycan derived nanoparticles are a promising delivery system owing to their unique tumour targeting ability. Exploiting fluorescein for inducing amphiphilicity in these biopolymers provides inherent imaging and drug stabilization capabilities by pi-pi stacking interactions with aromatic antineoplastic agents. This offers a versatile and highly customizable nanocarrier with narrow size distribution and high drug loading efficiency (80%) with sustained drug release.
Place, publisher, year, edition, pages
2016. Vol. 4, no 9, 1310-1313 p.
IdentifiersURN: urn:nbn:se:uu:diva-304544DOI: 10.1039/c6bm00335dISI: 000382116200003PubMedID: 27431007OAI: oai:DiVA.org:uu-304544DiVA: diva2:1033413
FunderEU, FP7, Seventh Framework Programme, 602699