Two-dimensional acoustic focusing of microparticles in two-phase droplet-based microfluidic systems for improved particle positioning within spherical droplets
2016 (English)Conference paper, Poster (Refereed)
We have fabricated a silicon-glass microfluidic two-phase droplet generator capable of generating sub 100-micrometer-sized (⌀ ൌ74 μm ± 2 μm) spherical droplets at rates up to hundreds of hertz (298 Hz ± 85 Hz). Furthermore, we have implemented a two-dimensional acoustic focusing technique into the device. Here, we show that applying the focusing to 10 μm sized polystyrene particles during the droplet generation step, results in a fourfold improvement of the particle positioning (centricity) within the generated droplets compared to the unactuated control. Finally, the efficiency of the system has been optimized by incorporating aluminum matching layers in the transducer design permitting biocompatible operational temperatures (<37°C).
Place, publisher, year, edition, pages
Engineering and Technology
Research subject Engineering Science with specialization in Microsystems Technology
IdentifiersURN: urn:nbn:se:uu:diva-305658OAI: oai:DiVA.org:uu-305658DiVA: diva2:1038840
27th Micromechanics and Microsystems Europe Workshop (MME 2016), Cork, Ireland. August 28-30th.
FunderSwedish Research Council