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Role and analysis of monocyte subsets in cardiovascular disease Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis"
Univ Munich, Inst Cardiovasc Prevent, Munich, Germany.;Partner Site Munich Heart Alliance, German Ctr Cardiovasc Res, Munich, Germany..
Univ Birmingham, Inst Cardiovasc Sci, City Hosp, Birmingham, W Midlands, England..
Univ Munich, Inst Cardiovasc Prevent, Munich, Germany..
Hop Xavier Bichat, INSERM, Paris, France..
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2016 (English)In: Thrombosis and Haemostasis, ISSN 0340-6245, Vol. 116, no 4, p. 626-637Article in journal (Refereed) Published
Abstract [en]

Monocytes as cells of the innate immunity are prominently involved in the development of atherosclerotic lesions. The heterogeneity of blood monocytes has widely been acknowledged by accumulating experimental and clinical data suggesting a differential, subset-specific contribution of the corresponding subpopulations to the pathology of cardiovascular and other diseases. This document re-evaluates current nomenclature and summarises key findings on monocyte subset biology to propose a consensus statement about phenotype, separation and quantification of the individual subsets.

Place, publisher, year, edition, pages
2016. Vol. 116, no 4, p. 626-637
Keyword [en]
Atherosclerosis, leukocyte function / activation, monocytes
National Category
Hematology Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:uu:diva-307281DOI: 10.1160/TH16-02-0091ISI: 000384964200009PubMedID: 27412877OAI: oai:DiVA.org:uu-307281DiVA: diva2:1046319
Available from: 2016-11-14 Created: 2016-11-11 Last updated: 2017-11-29Bibliographically approved

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