Lymphatic vascular morphogenesis
2014 (English)In: Molecular Mechanisms of Angiogenesis: From Ontogenesis to Oncogenesis, Springer Publishing Company, 2014, 25-44 p.Chapter in book (Refereed)
Lymphatic vessels participate in tissue homeostasis and immune surveillance by draining excess fluid and immune cells from tissues to blood circulation. Impaired lymphatic function can lead to tissue swelling, or lymphoedema, and associated complications, such as chronic inflammation and fat accumulation. The critical role of lymphatic vessels in a number of pathological conditions, including tumour metastasis, has led to an interest in identifying signalling pathways regulating lymphatic vessel development and growth. Here, we review the current knowledge on the molecular mechanisms of lymphatic development and how lymphatic vasculature contributes to diseases.
Place, publisher, year, edition, pages
Springer Publishing Company, 2014. 25-44 p.
Cancer and Oncology
IdentifiersURN: urn:nbn:se:uu:diva-307102DOI: 10.1007/978-2-8178-0466-8_2ScopusID: 2-s2.0-84930024214ISBN: 9782817804668ISBN: 9782817804651OAI: oai:DiVA.org:uu-307102DiVA: diva2:1048660