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Novel device, a temporary guidewire fixator
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Vascular Surgery.
2016 (English)In: Vascular, ISSN 1708-5381, E-ISSN 1708-539X, Vol. 24, no 6, 604-609 p.Article in journal (Refereed) Published
Abstract [en]

A novel device for distal fixation of a guidewire was tested in regards to deployment and retrieval, deposition in the blood stream and force of fixation in a pig model. Eleven pigs were subjected to full anaesthesia and heparinized to active clotting time 250-350 s. Uninterrupted blood flow during 4 h deposition was assessed by angiography and inspected for thrombus deposition upon retrieval. The force of fixation was investigated up to the level of loss of fixation (displacement force). The device was successfully deployed and retrieved in over 40 cases. In one case, an alternative method for bailout retrieval was used. Deposition for 4 h was performed, and uninterrupted blood flow was verified by angiography. No instances of arterial occlusion or thrombosis were detected. The median dislocation force was 7.6 N. No arterial rupture or dissection was detected following the loss of fixation. As a conclusion, the device was considered safe and functional in this animal test model.

Place, publisher, year, edition, pages
2016. Vol. 24, no 6, 604-609 p.
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:uu:diva-308342DOI: 10.1177/1708538116629265ISI: 000393226600006PubMedID: 26864777OAI: oai:DiVA.org:uu-308342DiVA: diva2:1049438
Funder
VINNOVA, 2012-00374
Available from: 2016-11-24 Created: 2016-11-24 Last updated: 2017-04-13Bibliographically approved

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