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Human immunodeficiency virus type 1 proteinase resistance to symmetric cyclic urea inhibitor analogs
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Biochemistry.
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Biochemistry.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Medicinal Chemistry. (Organic Pharmaceutical Chemistry)
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1997 (English)In: Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, E-ISSN 1098-6596, Vol. 41, no 11, 2383-2388 p.Article in journal (Refereed) Published
Abstract [en]

Resistant virus was isolated from virus propagated in cell culture in the presence of the human immunodeficiency virus type 1 (HIV-1) proteinase inhibitor DMP 323, Ro 31-8959, or A-75925. The proteinase gene of resistant virus was sequenced, and key muta

Place, publisher, year, edition, pages
1997. Vol. 41, no 11, 2383-2388 p.
Keyword [en]
PROTEASE INHIBITORS; HIV PROTEINASE; IN-VIVO; REPLICATION; PATTERNS; DESIGN
Identifiers
URN: urn:nbn:se:uu:diva-77602OAI: oai:DiVA.org:uu-77602DiVA: diva2:105514
Available from: 2006-03-01 Created: 2006-03-01 Last updated: 2017-12-14Bibliographically approved

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http://aac.asm.org/cgi/content/abstract/41/11/2383

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Danielson, U. Helena

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